Jonathan Louis Forman

US Patent:

6436647, Aug 20, 2002

Filed:

Mar 19, 2001

Appl. No.:

09/812706

Inventors:

Calvin F. Quate - Stanford CA
Mark O. Trulson - San Jose CA
Scott R. Manales - Santa Barbara CA
Jonathan E. Forman - San Jose CA

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C12Q 168

US Classification:

435 6, 435526

Abstract:

A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i. e. , a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.

US Patent:

20020137084, Sep 26, 2002

Filed:

Feb 5, 2002

Appl. No.:

10/072414

Inventors:

Calvin Quate - Stanford CA, US
Mark Trulson - San Jose CA, US
Scott Manalis - Santa Barbara CA, US
Jonathan Forman - San Carlos CA, US

International Classification:

C12Q001/68
G01N033/53
C12M001/34

US Classification:

435/006000, 435/007100, 435/287200

Abstract:

A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i.e., a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.

US Patent:

20050164289, Jul 28, 2005

Filed:

Mar 18, 2005

Appl. No.:

11/084306

Inventors:

Calvin Quate - Stanford CA, US
Mark Trulson - San Jose CA, US
Scott Manalis - Santa Barbara CA, US
Jonathan Forman - San Jose CA, US

Assignee:

Affymetrix, INC. - Santa Clara CA

International Classification:

C12Q001/68
C12M001/34

US Classification:

435006000, 435287200

Abstract:

A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i.e., a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.

US Patent:

20090131268, May 21, 2009

Filed:

Sep 15, 2008

Appl. No.:

12/211103

Inventors:

Paul Hardenbol - San Francisco CA, US
Jonathan E. Forman - San Carlos CA, US
George Karlin-Neumann - Palo Alto CA, US
Xin Miao - Menlo Park CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C40B 30/04

US Classification:

506 9

Abstract:

The invention provides method for genotyping specific sets of polymorphisms in a single multiplex reaction. The polymorphisms are selected to be of interest in detecting genetic variation that alters individuals' metabolism, distribution, extretion and transport of pharmacological compounds. In preferred aspects the genotyping employs a multiplex hybridization-based assay. In some aspects combinations of methods are employed to allow the combination of polymorphisms to be interrogated. The invention also provides nucleic acid standards for validating the performance of such hybridization-based assays.

US Patent:

62039830, Mar 20, 2001

Filed:

Jun 16, 1998

Appl. No.:

9/097675

Inventors:

Calvin F. Quate - Stanford CA
Mark O. Trulson - San Jose CA
Scott R. Manales - Santa Barbara CA
Jonathan E. Forman - San Jose CA

Assignee:

Affymetrix, Inc.

International Classification:

C12Q 168
G01N 33553

US Classification:

435 6

Abstract:

A method of using micromechanical devices as sensors for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners is provided. The method is useful whether the reactions occur through electrostatic forces or other forces. Induced stress, heat, or change in mass is detected where a binding partner is placed on a cantilever for possible reaction with an analyte molecules (i. e. , a non-identical binding partner). The method is particularly useful in determining DNA hybridization but may be useful in detecting interaction in any chemical assay.

US Patent:

20210317174, Oct 14, 2021

Filed:

Jun 23, 2021

Appl. No.:

17/356214

Inventors:

Jonathan FORMAN - , US
- Pittsburgh PA, US
Pooja AGARWAL - Mars PA, US
Jonathan FORMAN - Lafayette CA, US

International Classification:

C07K 14/47
A61P 11/00
A61K 38/17
A61K 48/00
C12N 15/86
A61K 9/00

Abstract:

The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding a cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide (e.g., a human CFTR polypeptide); viruses comprising the recombinant nucleic acids; compositions and formulations comprising the recombinant nucleic acids and/or viruses; methods of their use (e.g., for the treatment of a chronic lung disease, such as cystic fibrosis); and articles of manufacture or kits thereof.

US Patent:

20140164160, Jun 12, 2014

Filed:

Nov 26, 2013

Appl. No.:

14/090893

Inventors:

Jonathan Forman - Mt. Vernon NY, US

International Classification:

G06Q 30/06

US Classification:

705 261

Abstract:

The present invention generally relates to software driven, application (“app”)-based methods of gift giving, and more particularly to app-based methods for charitable donation-driven gift fulfillment via computing or mobile devices such as desktop, mobile, smartphones, and the like.