Jonathan Li

US Patent:

8438124, May 7, 2013

Filed:

Oct 18, 2007

Appl. No.:

11/874882

Inventors:

Nova Spivack - Tarrytown NY, US
Jonathan Qiang Li - San Francisco CA, US
Chris Jones - Mill Valley CA, US
Peter Royal - San Francisco CA, US
Lew Tucker - San Francisco CA, US
Scott White - Seattle WA, US
Jim Wissner - San Francisco CA, US

Assignee:

Evri Inc. - Seattle WA

International Classification:

G06F 17/00
G06N 5/00

US Classification:

706 45

Abstract:

Systems and methods of a knowledge management networking are disclosed here. In one aspect, embodiments of the present disclosure include a method, which may be implemented on a system, of hosting a web-space having a plurality of objects, the plurality of objects to include one or more of, representations of a set of users, a set of web-items, and a set of nets; wherein a net of the set of nets is a subset of the web-space comprising a sub-plurality of the plurality of objects. One embodiment can include, tracking an explicit relationship between a first set of at least two objects of the set of objects; the explicit relationship to be pre-determined by a user of the set of users, identifying an implicit relationship between a second set of at least two objects of the set of objects; the implicit relationship to be identified based on a semantic relationship between the at least two objects, and determining a default set of privacy rules governing access between the at least two objects based on one or more of the identified explicit relationship and the implicit relationship.

US Patent:

20030204507, Oct 30, 2003

Filed:

Apr 25, 2002

Appl. No.:

10/132626

Inventors:

Jonathan Li - Redwood City CA, US
David Smith - San Jose CA, US
Lee Barford - San Jose CA, US
John Heumann - Loveland CO, US

International Classification:

G06N005/00

US Classification:

707/100000

Abstract:

Hierarchical classification of samples. First stage classification identifies most members of the majority class and removes them from further consideration. Second stage classification then focuses on discriminating between the minority class and the greatly reduced number of majority class samples lying near the decision boundary.

US Patent:

20050207655, Sep 22, 2005

Filed:

Mar 22, 2004

Appl. No.:

10/805748

Inventors:

Nasreen Chopra - Belmont CA, US
Jonathan Li - Mountain View CA, US
Izhak Baharav - San Jose CA, US

International Classification:

G06K009/68
G06K009/00

US Classification:

382218000

Abstract:

An inspection system inspects features of an object using a feedback mechanism. The inspection system includes a processor that receives image data representing the object. The processor is operable to determine parameter modification information from the image data and modify an image parameter used during the production of the image data with the parameter modification information. The modified image parameter is used during the production of subsequent image data representing the object.

US Patent:

20210332444, Oct 28, 2021

Filed:

Apr 16, 2021

Appl. No.:

17/233423

Inventors:

Qing Sun - Richmond CA, US
Michael Y. Sha - Castro Valley CA, US
Hui Ren - Richmond CA, US
Jonathan Li - Richmond CA, US
Aiguo Zhang - San Ramon CA, US

International Classification:

C12Q 1/70

Abstract:

The present invention provides synthetic nucleic acid sequences comprising 10-30 nucleotides of the N1 and N2 gene regions and/or the 3′ non-coding region of the SARS-associated coronavirus Cov-2 (SARS-CoV-2) genome, and a synthetic nucleic acid sequence comprising 10-30 nucleotides of a nucleic acid sequence that is complementary to at least one of those regions. Also provided are compositions comprising the sequences, and uses of the sequences in diagnostic kits. The present invention further provides a primer and probe set for determining the presence or absence of SARS-associated coronavirus Cov-2 in a biological sample, wherein the primer set comprises at least one of the synthetic nucleic acid sequences. Also provided are a composition comprising the primer and probe set, and use of the primer and probe set in a diagnostic kit. Finally, the present invention provides kits and methods for determining the presence or absence of SARS-associated coronavirus Cov-2 (SARS-CoV-2) in a biological sample.

US Patent:

20180118824, May 3, 2018

Filed:

Nov 21, 2017

Appl. No.:

15/819423

Inventors:

- Rockville MD, US
Jonathan Li - Millbrae CA, US
Francine Zhifen Chen - San Francisco CA, US
Leslie S. Johnson - Darnestown MD, US
Kalpana Shah - Boyds MD, US
Ezio Bonvini - Potomac MD, US

Assignee:

MacroGenics, Inc. - Rockville MD

International Classification:

C07K 16/28
C07K 16/30
A61K 39/00

Abstract:

The present invention is directed to bi-specific monovalent diabodies that comprise two polypeptide chains and which possess at least one binding site specific for an epitope of CD3 and one binding site specific for an epitope of gpA33 (i.e., a “gpA33×CD3 bi-specific monovalent diabody”). The present invention also is directed to bi-specific monovalent diabodies that comprise an immunoglobulin Fc Domain (“bi-specific monovalent Fc diabodies”) and are composed of three polypeptide chains and which possess at least one binding site specific for an epitope of gpA33 and one binding site specific for an epitope of CD3 (i.e., a “gpA33×CD3 bi-specific monovalent Fc diabody”). The bi-specific monovalent diabodies and bi-specific monovalent Fc diabodies of the present invention are capable of simultaneous binding to gpA33 and CD3. The invention is directed to pharmaceutical compositions that contain such bi-specific monovalent diabodies or such bi-specific monovalent Fc diabodies. The invention is additionally directed to methods for the use of such diabodies in the treatment of cancer and other diseases and conditions.

US Patent:

20160222105, Aug 4, 2016

Filed:

Aug 20, 2014

Appl. No.:

14/913654

Inventors:

- Rockville MD, US
Jonathan Li - Millbrae CA, US
Francine Zhifen Chen - San Francisco CA, US
Leslie S. Johnson - Darnestown MD, US
Kalpana Shah - Boyds MD, US
Ezio Bonvini - Potomac MD, US

Assignee:

MacroGenics, Inc. - Rockville MD

International Classification:

C07K 16/28
C07K 16/30

Abstract:

The present invention is directed to bi-specific monovalent diabodies that comprise two polypeptide chains and which possess at least one binding site specific for an epitope of CD3 and one binding site specific for an epitope of gpA33 (i.e., a “gpA33×CD3 bi-specific monovalent diabody”). The present invention also is directed to bi-specific monovalent diabodies that comprise an immunoglobulin Fc Domain (“bi-specific monovalent Fc diabodies”) and are composed of three polypeptide chains and which possess at least one binding site specific for an epitope of gpA33 and one binding site specific for an epitope of CD3 (i.e., a “gpA33×CD3 bi-specific monovalent Fc diabody”). The bi-specific monovalent diabodies and bi-specific monovalent Fc diabodies of the present invention are capable of simultaneous binding to gpA33 and CD3. The invention is directed to pharmaceutical compositions that contain such bi-specific monovalent diabodies or such bi-specific monovalent Fc diabodies. The invention is additionally directed to methods for the use of such diabodies in the treatment of cancer and other diseases and conditions.

US Patent:

20150381440, Dec 31, 2015

Filed:

Sep 29, 2014

Appl. No.:

14/500954

Inventors:

Bin Zhao - Shanghai, CN
Jonathan Li - Palo Alto CA, US

International Classification:

H04L 12/26
H04L 29/06
H04L 29/08

Abstract:

Systems and methods for visualization of a call over network (CON) are provided. In some embodiments, the visualization of a call over network may be effectuated by three functionalities: a readiness dialog box that enables the facilitation of the call, the inclusion of visualization and participant features within the call, and a visualized summary after the call. The readiness dialog box is presented to the callers prior to the onset of the call. It presents the other participant's and their status. It also enables the caller to send messages (both preconfigured and customized) to the other participants. Once sufficient participants have joined, the call may start. Once the call starts, it may be visualized by displaying on a single or multi channels, which caller is speaking, and any additional indications they may be providing. The caller may likewise be provided a set of participant features that allow the user to interact with the call. After the call concludes, a visualized summary of the call can then be generated. The summary includes any of the recording, transcriptions, scenario information, speaker information and the duration each speaker was talking, etc.

US Patent:

20150381816, Dec 31, 2015

Filed:

Sep 29, 2014

Appl. No.:

14/500968

Inventors:

Bin Zhao - Shanghai, CN
Jonathan Li - Palo Alto CA, US

International Classification:

H04M 3/56
H04M 3/432

Abstract:

Systems and methods for a readiness dialog box for a call over network (CON) are provided. In some embodiments, the readiness dialog box is presented to the callers prior to the onset of the call. It presents the other participant's and their status. For example, it may indicate which participants are online, but not yet ready, those who are ready, and those not available. It also enables the caller to send messages (both preconfigured and customized) to the other participants. Once sufficient participants have joined, the call may start. Sufficiency of participants could include a quorum of individuals, may require that specific participants are ready, everyone is ready, or may be time dependent. The participant requirements may be configured by the individual setting up the call based upon call type.