Jordan N Miller

US Patent:

20120058174, Mar 8, 2012

Filed:

Aug 17, 2011

Appl. No.:

13/211478

Inventors:

Jennifer L. West - Houston TX, US
Christopher S. Chen - Princeton NJ, US
Jordan S. Miller - Philadelphia PA, US
Michael T. Yang - Philadelphia PA, US

International Classification:

A61K 9/70
A61K 35/00
A61K 38/00
B29C 47/00
A61K 35/12
B29D 7/01
C03C 25/68
B05D 5/00
A61K 9/00
A61K 31/7088

US Classification:

424443, 424400, 424 931, 514 11, 514 44 R, 424 937, 264 458, 216 7, 427243, 264465

Abstract:

Methods of fabricating a substantially interconnected model vasculature, as well as compositions formed from such methods are provided. In some embodiments, the methods may comprise forming a non-woven fiber network comprising a plurality of fibers and a void space; backfilling the void space of the fiber network; and removing the fibers to form a substantially interconnected vascular network.

US Patent:

20220378570, Dec 1, 2022

Filed:

May 23, 2022

Appl. No.:

17/751029

Inventors:

- Houston TX, US
Jordan MILLER - Houston TX, US

International Classification:

A61F 2/06
A61L 27/50
A61L 27/28
B29C 39/12
B29C 39/38
B22D 19/00
B33Y 80/00

Abstract:

A method of preparing a structure is provided. The method includes providing an initial structure; casting a first material in one or more void volumes of the initial structure; removing the initial structure from the first material; obtaining a cast structure comprising the first material; coating a second material on the cast structure; casting a third material using the coated cast structure; removing the first material; and obtaining a final structure. In various embodiments, the initial structure can include a first initial structure and a second initial structure and casting a first material in one or more first void volumes of the first initial structure and in one or more second void volumes of the second initial structure. In various embodiments, the method includes assembling the first cast structure and the second cast structure and obtaining an assembled structure comprising the first cast structure and the second cast structure.

US Patent:

20220339858, Oct 27, 2022

Filed:

Apr 26, 2022

Appl. No.:

17/729061

Inventors:

- Houston TX, US
Matthew Kenneth GELBER - Houston TX, US
Bagrat GRIGORYAN - Houston TX, US
Jordan MILLER - Houston TX, US

International Classification:

B29C 64/124
B33Y 10/00
B33Y 30/00

Abstract:

Provided herein is a system for producing a product. The system generally comprises a large-area micro-stereolithography system and a layer leveling system. The large-area micro-stereolithography system is capable of generating the product by optically polymerizing successive layers of a curable resin at a print plane. The layer leveling system is capable of flattening a non-flat region (such as a meniscus) of the curable resin in a vicinity of the build plane.

US Patent:

20220339882, Oct 27, 2022

Filed:

Apr 26, 2022

Appl. No.:

17/729047

Inventors:

- Houston TX, US
Jordan MILLER - Houston TX, US

International Classification:

B29C 64/393
B33Y 10/00
B33Y 30/00
B33Y 50/02
B29C 64/135
B29C 64/268

Abstract:

Provided herein is a system for producing a product. The system generally comprises a large-area micro-stereolithography system, an optical imaging system, and a controller in communication with the large-area micro-stereolithography system and the optical imaging system. The large-area micro-stereolithography system is capable of generating the product by optically polymerizing successive layers of a curable resin at a build plane. The controller is capable of directing the optical imaging system to obtain one or more optical images of the product or of a reference component located at the build plane, and adjusting a parameter associated with the large-area micro-stereolithography system based on the one or more images.

US Patent:

20220339883, Oct 27, 2022

Filed:

Apr 26, 2022

Appl. No.:

17/729077

Inventors:

- Livermore CA, US
- Houston TX, US
Matthew Kenneth GELBER - Houston TX, US
Jordan MILLER - Houston TX, US

International Classification:

B29C 64/393
B29C 64/124
B33Y 10/00
B33Y 50/02
B33Y 30/00

Abstract:

Provided herein is a system for producing a product. The system generally comprises a large-area micro-stereolithography system, an optical imaging system, and a controller in communication with the large-area micro-stereolithography system and the optical imaging system. The large-area micro-stereolithography system is capable of generating the product by optically polymerizing successive layers of a curable resin at a build plane. The controller is capable of analyzing a focus level of the reference target based on the captured image; and based on the analyzing, adjusting a focus property of the projected image beam of the stereolithography system.

US Patent:

20220257827, Aug 18, 2022

Filed:

Jul 23, 2020

Appl. No.:

17/629621

Inventors:

- Houston TX, US
Jordan S. Miller - Houston TX, US
Bagrat Grigoryan - Houston TX, US
Candice Sears - Houston TX, US

International Classification:

A61L 27/18
A61L 27/58
C08G 63/08
C08K 5/00
C08K 5/09
C08J 3/24
B29C 64/129

Abstract:

Various precursor solutions and methods of 3D printing and other additive manufacturing approaches are provided for the manufacture of articles using photocrosslinkable vinyl shape memory polymers. In various aspects, articles are manufactured by a process comprising (i) exposing a precursor solution to an intensity and frequency of light to initiate photo-polymerization of the precursor solution to form a layer of the article; and (ii) repeating step (i) a number of times to form the article in a layer-by-layer approach; wherein the precursor solution comprises a first polymeric precursor comprising a plurality of vinyl terminated side-chains attached thereto. A vinyl-functionalized, photocrosslinkable SMP used as an example herein is a novel variant of a previously disclosed SMP composition, with higher amounts of vinyl functionalization but similar thermomechanical properties to the SMP library previously disclosed. Moreover, a unique combination of chemistries is disclosed that incorporates the aforementioned vinyl-functionalized SMPs along with acrylate-based crosslinkers. Additional novel compositions are disclosed containing the vinyl-functionalized SMPs with additional dithiol functionalizations, vinyl-functionalized SMPs with dithiol crosslinkers, as well as vinyl-functionalized SMPs with both acrylate-based and dithiol crosslinkers, as another means to tune degradation rates and other material properties. The articles can include a variety of articles such as stents, grafts, external sheaths, and the like. Beneficially, the printed articles can include a plurality of pores having an average diameter of about 50 pm to about 5000 pm, about 500 pm to about 2000 pm, or about 1000 pm even in the absence of a photoblocker.

US Patent:

20230095466, Mar 30, 2023

Filed:

Sep 20, 2022

Appl. No.:

17/933592

Inventors:

- Rock Hill SC, US
Jordan MILLER - Houston TX, US
Selene ALIKAH - Houston TX, US
Matthew GELBER - Houston TX, US
Faraz JIVAN - Houston TX, US
Andres RUIZ - Houston TX, US
Jacob SNOOK - Houston TX, US

Assignee:

3D SYSTEMS, INC. - Rock Hill SC

International Classification:

B01L 3/00

Abstract:

Some embodiments of the disclosure disclose manifolds, microfluidic systems and methods that provide control over fluid flow distribution to an array of bio-scaffolds contained within the manifolds. In some embodiments, multiple perfusates may be injected into the manifold via multiple inlets where the manifold contains a bio-assembly with a substrate having a bio-scaffold disposed thereon. Biological investigations of the perfusates may then be conducted in the vascular components and chambers of the bio-scaffold.

US Patent:

20210348104, Nov 11, 2021

Filed:

May 4, 2021

Appl. No.:

17/307880

Inventors:

- Houston TX, US
Jordan Miller - Houston TX, US
Matthew Gelber - Houston TX, US

International Classification:

C12M 1/12
C12M 1/00
G01N 33/50
C12N 5/00

Abstract:

A bio-assembly, a kit for a bio-assembly and methods of using the same are provided. The bio-assembly includes a substrate and a bio-scaffold affixed to the substrate. In accordance with various embodiments, a loader plate having a partition or a loader and a plate having a partition are provided. In accordance with various embodiments, the loader plate includes a partition outlet and a partition inlet, wherein the partition outlet and the partition inlet in fluid communication with the gel. In accordance with various embodiments, the partition comprising an internal volume and shaped to receive the bio-scaffold, and the loader includes a loader inlet and a loader outlet in fluid communication with the gel. In accordance with various embodiments, a bio-compatible adhesive positioned between the substrate and the loader plate or plate. In accordance with various embodiments, a fluid mixture is injected into the bio-scaffold.