- Burlington NC, US Jose S. Gil - Winnetka CA, US Matthew J. Brown - Burlington NC, US
International Classification:
G01N 33/569 G01N 33/58
Abstract:
Disclosed herein are methods, compositions, kits, and systems for rapid multiplex detection of a microorganism of interest. Recombinant bacteriophages encoding capture moiety-indicator protein fusion products allow for the capture of indicator proteins on a surface. Cocktail compositions of recombinant bacteriophages can be used to detect potentially harmful bacteria. The specificity of recombinant bacteriophages for binding microorganisms allows targeted and highly specific detection of a microorganism of interest.
Methods And Systems For The Rapid Detection Of Listeria Using Infectious Agents
- Burlington NC, US Jose S. Gil - Winnetka CA, US Matthew J. Brown - Burlington NC, US Minh Mindy Bao Nguyen - Shoreview MN, US Wendy Hahn - Hugo MN, US
International Classification:
C12N 7/00 C12N 15/86 C12Q 1/70
Abstract:
Disclosed herein are methods and systems for rapid detection of microorganisms such as spp. in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene in the late gene region. The specificity of the bacteriophage, such as -specific bacteriophage, allows detection of a specific microorganism, such as spp. and an indicator signal may be amplified to optimize assay sensitivity.
Methods And Systems For The Detection Of Microorganisms Using Infectious Agents
Disclosed herein are methods, compositions, kits, and systems for rapid detection of a microorganism of interest on a surface, including medical devices. Cocktail compositions of recombinant bacteriophages can be used to detect potentially harmful bacteria. The specificity of recombinant bacteriophages for binding microorganisms allows targeted and highly specific detection of a microorganism of interest.
Methods For The Diagnosis And Treatment Of Biofilm-Related Infections
Disclosed herein are methods and systems for rapid diagnosis and treatment of biofilm-related infections in a subject having a medical implant. A reporter cocktail composition is disclosed herein and may be used to detect a microorganism of interest and determine the presence of an infection. A therapeutic cocktail composition is also disclosed herein and may be used to treat a subject diagnosed with a biofilm-related infection.
Methods And Systems For The Rapid Detection Of Microorganisms Using Recombinant Infectious Agents To Express An Indicator Subunit
- Burlington NC, US Jose S. Gil - Winnetka CA, US Wendy Hahn - Hugo MN, US Dwight L. Anderson - Minneapolis MN, US
International Classification:
C12Q 1/04 C12Q 1/66
Abstract:
Disclosed herein are methods and systems for rapid detection of microorganisms such as bacteria in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene encoding one subunit of an indicator protein. The specificity of the bacteriophage allows detection of a particular bacteria of interest and an indicator signal may be amplified to optimize assay sensitivity.
Devices And Methods For Detecting Microorganisms Using Recombinant Reproduction-Deficient Indicator Bacteriophage
- Burlington NC, US Jose S. Gil - Winnetka CA, US Minh Mindy Bao Nguyen - Shoreview MN, US Wendy S. Hahn - Hugo MN, US
International Classification:
C12Q 1/10 C12N 7/00 C12Q 1/66
Abstract:
Disclosed herein are compositions, methods, kits and systems for rapid detection of microorganisms using a reproduction-deficient indicator bacteriophage. The specificity of such reproduction-deficient indicator bacteriophage for binding and infecting particular microorganisms of interest allows targeted and sensitive detection of a microorganism of interest.
Methods And Systems For The Rapid Detection Of Listeria Using Infectious Agents
Disclosed herein are methods and systems for rapid detection of microorganisms such as Listeria spp. in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene in the late gene region. The specificity of the bacteriophage, such as Listeria-specific bacteriophage, allows detection of a specific microorganism, such as Listeria spp. and an indicator signal may be amplified to optimize assay sensitivity.
Methods And Systems For Rapid Detection Of Microorganisms Using Infectious Agents
- Burlington NC, US Jose S. Gil - Winnetka CA, US Ben Barrett Hopkins - Sherman Oaks CA, US Stephen Erickson - White Bear Township MN, US
Assignee:
Laboratory Corporation of America Holdings - Burlington NC
International Classification:
C12Q 1/66 G01N 33/569 G01N 33/58 C12N 15/86
Abstract:
Disclosed herein are methods and systems for rapid detection of microorganisms in a sample, without culturing for enrichment of the microorganism. A modified bacteriophage is also disclosed which comprises a non-native indicator gene in the late gene region. The indicator product is not a fusion protein. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
The Yankees also optioned left-hander Cesar Cabral and right-hander Shane Greene to Scranton/Wilkes-Barre. Right-hander Matt Daley, catcher Jose Gil, infielder Zelous Wheeler, and outfielders Antoan Richardson and Adonis Garcia were sent to minor league camp.
True, major-league veteran Gustavo Molina and the quite capable Jose Gil, who likely will be a big-league backup for some team in a few years, were hurt. Farnham, however, was quite familiar with Pettitte.
Alex Rodriguez had an RBI groundout in the first and a run-scoring double in the second for the Yankees. Jose Gil went 2-for-2 to up his average to .800. Michael Bourn went 2-for-3 with a double for Atlanta.
Date: Mar 10, 2012
Category: Sports
Source: Google
Yankees CF Curtis Granderson could miss opening day with strained side muscle
LHP Pedro Felicino (sore upper left arm) threw 20 pitches in batting practice and expects to pitch in game Friday or Saturday. ... The Yankees optioned INFs Brandon Laird and Kevin Russo, and OF Greg Golson to triple-A Scranton/Wilkes-Barre. OF Melky Mesa was optioned to double-A Trenton, while C Jose Gil, INF Jorge Vazquez, and OF Jordan Parraz were sent to the minor league camp.