Joseph A Bohn

US Patent:

44580207, Jul 3, 1984

Filed:

Nov 15, 1982

Appl. No.:

6/441605

Inventors:

Joseph W. Bohn - San Diego CA
Peter A. Cohen - San Diego CA
Bruce L. Zuraw - Del Mar CA

Assignee:

Quidel - La Jolla CA

International Classification:

G01N 3354
G01N 3358

US Classification:

435296

Abstract:

A system for conducting an immunoassay in a single chamber, by concentrating antibodies for antigenic components on microbeads treated for binding immunological components, physically separating the fluid from which the immunological active component is separated, and determining the amount of immunological component collected on the beads, comprising a multiple-chamber dispensing cylinder.

US Patent:

44242794, Jan 3, 1984

Filed:

Aug 12, 1982

Appl. No.:

6/407454

Inventors:

Joseph W. Bohn - San Diego CA
Peter A. Cohen - San Diego CA
Bruce L. Zuraw - Del Mar CA

Assignee:

Quidel - La Jolla CA

International Classification:

G01N 3354
G01N 3358

US Classification:

436534

Abstract:

A method and apparatus for conducting an immunoassay. The apparatus features a cylindrical tube having one open end into which a plunger filter assembly is slidably fitted. The filter assembly is composed of a plunger filter cylinder open at both ends, a seal fixed to the proximal end of the plunger filter cylinder and a dome-shaped filter inside of and closing the proximal end of the plunger filter cylinder, and beads sensitized with an immunologically reactive material, such as an antibody.