Robert Glenn Dennis - Chapel Hill NC, US Thomas H. Fischer - Hillsborough NC, US Joseph Anthony DaCorta - Chapel Hill NC, US
Assignee:
ENTEGRION, INC. - Research Triangle Park NC
International Classification:
C12Q 1/56 C12M 1/34 C12Q 1/02
US Classification:
435 13, 4352873, 435 29
Abstract:
A device, system and method is disclosed in which small volume blood samples are subjected to shear forces and shear stresses between two parallel planar surfaces to which linear motion trajectories are imparted. The formation of clots or coagulation of the sample is measured from dynamic mechanical coupling which occurs between the two parallel planar surfaces. Detection of the coagulation response can be achieved through optical probing or by measurement of physical effects of the blood sample binding to the planar surfaces, and restricting movement thereof.
Spray-Dried Blood Products And Methods Of Making Same
The present invention is directed to a method of preparing dehydrated blood products, comprising the steps of: (a) providing a hydrated blood product; (b) spray-drying the hydrated blood product to produce a dehydrated blood product, as well as dehydrated blood products made by the method. The present invention is directed to a method of treating a patient suffering from a blood-related disorder, comprising the steps of: (a) rehydrating a therapeutic amount of the dehydrated blood products to produce a rehydrated therapeutic composition; and (b) administering the rehydrated therapeutic composition to the patient. The present invention is directed to a bandage or surgical aid comprising the dehydrated blood products described above.
Portable Coagulation Monitoring Device For Assessing Coagulation Response
Thomas H. Fischer - Hillsborough NC, US Joseph Anthony DaCorta - Chapel Hill NC, US
Assignee:
Entegrion, Inc. - Research Triangle Park NC
International Classification:
G01N 33/86
US Classification:
4352887
Abstract:
A device, system and method is disclosed in which small volume blood samples are subjected to shear forces and shear stresses between two parallel planar surfaces to which linear motion trajectories are imparted. The formation of clots or coagulation of the sample is measured from dynamic mechanical coupling which occurs between the two parallel planar surfaces. Detection of the coagulation response can be achieved through optical probing or by measurement of physical effects of the blood sample binding to the planar surfaces, and restricting movement thereof.
Fabric Compositions Comprising Attached Zeolite And/Or A Zeolite/Pectin Complex
The invention relates to fabric compositions with improved hemostatic properties comprising attached a zeolite, a zeolite/pectin complex, or a mixture thereof, and methods of preparing such fabric compositions.
- Washington DC, US - Williamsburg VA, US - Richmond VA, US Joseph Dacorta - King George VA, US Dorne Yager - Mechanicsville VA, US
International Classification:
A61L 15/44 A61L 15/40 A41D 13/11
Abstract:
The invention relates to antimicrobial and/or antiviral fabric compositions comprising ascorbic acid, citric acid, sodium hypophosphite, or a mixture thereof. The ascorbic acid may be covalently attached to at least one cellulosic portion of the fabric composition. The invention also relates to methods for preparing such fabric compositions.
Portable Coagulation Monitoring Devices, Systems, And Methods
- Durham NC, US Richard Hall - Chester, GB Joseph Anthony Dacorta - Chapel Hill NC, US
Assignee:
Entegrion, Inc. - Durham NC
International Classification:
G01N 33/86 G01N 33/49
Abstract:
Portable coagulation monitoring devices, systems, and methods are disclosed. Namely, a test cartridge is provided for use in a portable coagulation monitor (PCM) device. Further, the test cartridge comprises two glass-filled thermoplastic polymer plates and a disposable blood introduction device. The two glass-filled thermoplastic polymer plates are arranged substantially in parallel with a small gap therebetween for receiving a sample of blood to be tested. Using the PCM device, the two glass-filled thermoplastic polymer plates can be moved linearly relative to each other. Methods of measuring coagulation response in a blood sample using the test cartridge and the PCM device are provided. A method of introducing blood into the test cartridge using the disposable blood introduction device is provided.
Spray-Dried Blood Products And Methods Of Making Same
The present invention is directed to a method of preparing dehydrated blood products, comprising the steps of: (a) providing a hydrated blood product; (b) spray-drying the hydrated blood product to produce a dehydrated blood product, as well as dehydrated blood products made by the method. The present invention is directed to a method of treating a patient suffering from a blood-related disorder, comprising the steps of: (a) rehydrating a therapeutic amount of the dehydrated blood products to produce a rehydrated therapeutic composition; and (b) administering the rehydrated therapeutic composition to the patient. The present invention is directed to a bandage or surgical aid comprising the dehydrated blood products described above.
Portable Coagulation Monitoring Devices, Systems, And Methods
- RESEARCH TRIANGLE PARK NC, US RICHARD HALL - CHESTER, GB JOSEPH Anthony DACORTA - CHAPEL HILL NC, US
International Classification:
G01N 33/86 G01N 33/545
Abstract:
Portable coagulation monitoring devices, systems, and methods are disclosed. Namely, a test cartridge is provided for use in a portable coagulation monitor (PCM) device. Further, the test cartridge comprises two glass-filled thermoplastic polymer plates and a disposable blood introduction device. The two glass-filled thermoplastic polymer plates are arranged substantially in parallel with a small gap therebetween for receiving a sample of blood to be tested. Using the PCM device, the two glass-filled thermoplastic polymer plates can be moved linearly relative to each other. Methods of measuring coagulation response in a blood sample using the test cartridge and the PCM device are provided. A method of introducing blood into the test cartridge using the disposable blood introduction device is provided.
Name / Title
Company / Classification
Phones & Addresses
Joseph Dacorta Chief Technology Officer
Entegrion, Inc Noncommercial Research Organization