Joseph E Lucas

US Patent:

20120114661, May 10, 2012

Filed:

May 26, 2010

Appl. No.:

13/322232

Inventors:

Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Christopher W. Woods - Durham NC, US
Lawrence Carin - Durham NC, US
Aimee K. Zaas - Chapel Hill NC, US
Alfred Hero - Ann Arbor MI, US

International Classification:

A61K 39/42
A61K 31/24
A61P 31/12
A61K 31/351
C40B 30/00
C40B 30/04
C12Q 1/70
A61K 31/7088

US Classification:

4241471, 435 5, 514535, 514 44 A, 514459, 506 7, 506 9

Abstract:

Methods of identifying infectious disease infection prior to presentation of symptoms, assays for identifying genomic markers of infectious disease, and methods for diagnosing the underlying etiology of infectious disease.

US Patent:

20190376969, Dec 12, 2019

Filed:

Feb 2, 2018

Appl. No.:

16/483113

Inventors:

- Durham NC, US
Ricardo Henao Giraldo - Durham NC, US
Erik Soderblom - Raleigh NC, US
Joseph Lucas - Chapel Hill NC, US
Christopher W. Woods - Durham NC, US
Geoffrey S. Ginsburg - Durham NC, US

International Classification:

G01N 33/569
C07K 14/005
G01N 33/577

Abstract:

The present disclosure provides methods for determining the presence or absence of and/or the etiology of an acute respiratory viral infection in a subject, as well as methods of treating the subject based on the determination, by measuring on a platform the expression levels of a pre-defined set of gene products.

US Patent:

20160194715, Jul 7, 2016

Filed:

Dec 28, 2015

Appl. No.:

14/981547

Inventors:

- Durham NC, US
Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Hamza Aziz - Raleigh NC, US
John R. Perfect - Durham NC, US

International Classification:

C12Q 1/68

Abstract:

Methods for identifying fungal infection, assays for identifying genomic and protein markers of fungal infection, and methods for diagnosing the fungal infection. In one aspect, the method of identifying fungal infection by proteomic assay involves measuring the protein levels of proteins listed in Table 2A in a peripheral blood cell sample and comparing the determined protein levels to standard protein levels. In another aspect, subjects identified as being infected with fungal infection are treated with anti-fungals.

US Patent:

20150252417, Sep 10, 2015

Filed:

Sep 24, 2013

Appl. No.:

14/430635

Inventors:

- Durham NC, US
Joseph R. Nevins - Durham NC, US
Joseph Lucas - Durham NC, US
Holly K. Dressman - Durham NC, US

International Classification:

C12Q 1/68

Abstract:

The present invention relates, in general, to gene expression profiles, and in particular, to a gene expression profile of an environmental exposure, ionizing radiation. The invention further relates to methods of screening patients for radiation exposure based on gene expression profiling and to kits suitable for use in such methods.

US Patent:

20140323391, Oct 30, 2014

Filed:

Mar 15, 2014

Appl. No.:

14/214853

Inventors:

- Durham NC, US
Vance Fowler - Durham NC, US
Christopher W. Woods - Durham NC, US
Joseph E. Lucas - Chapel Hill NC, US
Geoffrey S. Ginsburg - Durham NC, US
Sun Hee Ahn - Gwangju, KR

Assignee:

Duke University - Durham NC

International Classification:

C12Q 1/68

US Classification:

514 27, 506 9, 514 23, 514192, 514200, 514457, 514 24, 514312, 514152, 514 29, 514 28

Abstract:

Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.