Joseph Benjamin Lucas

US Patent:

20120077767, Mar 29, 2012

Filed:

May 26, 2010

Appl. No.:

13/322237

Inventors:

Aimee K. Zaas - Chapel Hill NC, US
Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Hamza Aziz - Durham NC, US
John R. Perfect - Durham NC, US

International Classification:

A61K 31/7048
C40B 30/00
C12Q 1/68
A61K 31/4196
A61P 31/00
A61K 31/137
A61K 31/505
A61K 31/343
A61P 31/10
C12Q 1/04
A61K 31/496

US Classification:

514 31, 435 34, 506 7, 435 615, 435 613, 514383, 51425407, 514654, 514274, 514462

Abstract:

Methods for identifying fungal infection, assays for identifying genomic and protein markers of fungal infection, and methods for diagnosing the fungal infection. In one aspect, the method of identifying fungal infection by proteomic assay involves measuring the protein levels of proteins listed in Table 2A in a peripheral blood cell sample and comparing the determined protein levels to standard protein levels. In another aspect, subjects identified as being infected with fungal infection are treated with anti-fungals.

US Patent:

20120114661, May 10, 2012

Filed:

May 26, 2010

Appl. No.:

13/322232

Inventors:

Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Christopher W. Woods - Durham NC, US
Lawrence Carin - Durham NC, US
Aimee K. Zaas - Chapel Hill NC, US
Alfred Hero - Ann Arbor MI, US

International Classification:

A61K 39/42
A61K 31/24
A61P 31/12
A61K 31/351
C40B 30/00
C40B 30/04
C12Q 1/70
A61K 31/7088

US Classification:

4241471, 435 5, 514535, 514 44 A, 514459, 506 7, 506 9

Abstract:

Methods of identifying infectious disease infection prior to presentation of symptoms, assays for identifying genomic markers of infectious disease, and methods for diagnosing the underlying etiology of infectious disease.

US Patent:

20200063203, Feb 27, 2020

Filed:

May 16, 2019

Appl. No.:

16/414501

Inventors:

- Durham NC, US
Joseph E. Lucas - Chapel Hill NC, US
Thomas L. Ortel - Mebane NC, US
Richard C. Becker - Durham NC, US
Deepak Voora - Chapel Hill NC, US
Jen-Tsan Chi - Chapel Hill NC, US

International Classification:

C12Q 1/6883
G01N 33/68
A61K 31/60

Abstract:

Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to antiplatelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.

US Patent:

20190376969, Dec 12, 2019

Filed:

Feb 2, 2018

Appl. No.:

16/483113

Inventors:

- Durham NC, US
Ricardo Henao Giraldo - Durham NC, US
Erik Soderblom - Raleigh NC, US
Joseph Lucas - Chapel Hill NC, US
Christopher W. Woods - Durham NC, US
Geoffrey S. Ginsburg - Durham NC, US

International Classification:

G01N 33/569
C07K 14/005
G01N 33/577

Abstract:

The present disclosure provides methods for determining the presence or absence of and/or the etiology of an acute respiratory viral infection in a subject, as well as methods of treating the subject based on the determination, by measuring on a platform the expression levels of a pre-defined set of gene products.

US Patent:

20160194715, Jul 7, 2016

Filed:

Dec 28, 2015

Appl. No.:

14/981547

Inventors:

- Durham NC, US
Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Hamza Aziz - Raleigh NC, US
John R. Perfect - Durham NC, US

International Classification:

C12Q 1/68

Abstract:

Methods for identifying fungal infection, assays for identifying genomic and protein markers of fungal infection, and methods for diagnosing the fungal infection. In one aspect, the method of identifying fungal infection by proteomic assay involves measuring the protein levels of proteins listed in Table 2A in a peripheral blood cell sample and comparing the determined protein levels to standard protein levels. In another aspect, subjects identified as being infected with fungal infection are treated with anti-fungals.

US Patent:

20160097099, Apr 7, 2016

Filed:

Oct 12, 2015

Appl. No.:

14/880668

Inventors:

- Durham NC, US
Vance Fowler - Chapel Hill NC, US
Christopher W. Woods - Durham NC, US
Joseph E. Lucas - Chapel Hill NC, US
Geoffrey S. Ginsburg - Durham NC, US
Sun Hee Ahn - Gwangju, KR

International Classification:

C12Q 1/68

Abstract:

Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.

US Patent:

20150322514, Nov 12, 2015

Filed:

Sep 6, 2013

Appl. No.:

14/426430

Inventors:

- Durham NC, US
Joseph E. Lucas - Chapel Hill NC, US
Thomas L. Ortel - Mebane NC, US
Richard C. Becker - Durham NC, US
Deepak Voora - Chapel Hill NC, US
Jen-Tsan Chi - Chapel Hill NC, US

International Classification:

C12Q 1/68
A61K 31/60

Abstract:

Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to anti-platelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.

US Patent:

20150252417, Sep 10, 2015

Filed:

Sep 24, 2013

Appl. No.:

14/430635

Inventors:

- Durham NC, US
Joseph R. Nevins - Durham NC, US
Joseph Lucas - Durham NC, US
Holly K. Dressman - Durham NC, US

International Classification:

C12Q 1/68

Abstract:

The present invention relates, in general, to gene expression profiles, and in particular, to a gene expression profile of an environmental exposure, ionizing radiation. The invention further relates to methods of screening patients for radiation exposure based on gene expression profiling and to kits suitable for use in such methods.

Address:

912 Stoney Brk Dr, Sanford, NC 27330

VIN:

5NHUVH0177U322841

Make:

Infiniti

Model:

QX56 4dr AWD

Year:

2007