Erwin W. Gelfand - Englewood CO, US Joseph J. Lucas - Evergreen CO, US
Assignee:
National Jewish Medical and Research Center - Denver CO
International Classification:
C12Q 1/68
US Classification:
435 6, 435 723
Abstract:
Disclosed are methods for assessing tumor cell growth in a patient for the diagnosis, monitoring and/or staging of tumor development. The method include the identification of reduced cdk6 expression or biological activity as an indicator of increased cell growth in a cell sample. The methods further include the identification of compounds which regulate cdk6 and the use of such compounds in a method for the regulation of inappropriate cell growth.