Joseph A Metzger

US Patent:

20110033412, Feb 10, 2011

Filed:

Dec 17, 2008

Appl. No.:

12/747073

Inventors:

Rainer Ng - Seattle WA, US
Joseph M. Metzger - Minneapolis MN, US
Lorraine Reeve - Dexter MI, US
Bruce Markham - Novi MI, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
PHRIXUS PHARMACEUTICALS, INC. - Ann Arbor MI

International Classification:

A61K 31/77
A61K 31/785
A61P 21/00

US Classification:

424 783

Abstract:

The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing skeletal muscle deficiencies and injuries (e.g., dystrophin-deficient skeletal muscle; skeletal muscle having a contraction force deficit; skeletal muscle having a Ca imbalance; skeletal muscle having microtears).

US Patent:

20190294687, Sep 26, 2019

Filed:

May 14, 2018

Appl. No.:

15/978787

Inventors:

- Redmond WA, US
Jonathan Alexander BOCKELMAN - Kirkland WA, US
Marcelo Albuquerque MAS - Redmond WA, US
Joseph Arthur METZGER - Kirkland WA, US

International Classification:

G06F 17/30

Abstract:

A system enabling smart versioning of files is provided. Techniques disclosed herein enable a system to snap to new versions of a file based on one or more measures of user interactions with the file. For instance, a system can create a new version number for a file based on an amount of time a user has spent editing the file, a number of saves that have occurred, and/or a quantity of data applied to edits of the file. The techniques disclosed herein can also utilize telemetry data to fine tune weightings that are applied to data measuring specific types user activity to provide results that best serve a range of use scenarios and file types. By providing version numbers of a file that are based on user interactions, a system can provide more meaningful version numbers that are aligned with the contents of a file.