Joseph G Potter

US Patent:

6477410, Nov 5, 2002

Filed:

May 31, 2000

Appl. No.:

09/584138

Inventors:

Julian L. Henley - New Haven CT
Kuo Wei Chang - Waltham MA
Joseph Potter - Oak Bluffs MA
Dennis I. Goldberg - Boston MA
Christopher H. Porter - Woodinville WA
V. Lorenzo Porcelli - Ossining NY

Assignee:

BioPhoretic Therapeutic Systems, LLC - Framingham MA

International Classification:

A61N 130

US Classification:

604 20, 604 22, 604501, 601 1

Abstract:

An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site. In another form, the applicator is self-contained, having a power supply, a first electrode overlying a pad and a ground electrode from the opposite side from the pad whereby the individual presses the pad against the treatment site to complete the electrical circuit and electrokinetically drive the medicament into the treatment site.

US Patent:

6735470, May 11, 2004

Filed:

Sep 18, 2002

Appl. No.:

10/245337

Inventors:

Julian L. Henley - New Haven CT
Kuo Wei Chang - Waltham MA
Joseph Potter - Oak Bluffs MA
Dennis I. Goldberg - Boston MA
Christopher H. Porter - Woodinville WA
V. Lorenzo Porcelli - Ossining NY

Assignee:

BioPhoretic Therapeutic Systems, LLC - Framingham MA

International Classification:

A61N 130

US Classification:

604 20, 604 22, 604501, 601 1

Abstract:

An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site. In another form, the applicator is self-contained, having a power supply, a first electrode overlying a pad and a ground electrode from the opposite side from the pad whereby the individual presses the pad against the treatment site to complete the electrical circuit and electrokinetically drive the medicament into the treatment site.

US Patent:

6792306, Sep 14, 2004

Filed:

Apr 8, 2002

Appl. No.:

10/117346

Inventors:

Julian L. Henley - New Haven CT
Kuo Wei Chang - Waltham MA
Joseph Potter - Oak Bluffs MA
Dennis I. Goldberg - South Brookline MA

Assignee:

Biophoretic Therapeutic Systems, LLC - Framingham MA

International Classification:

A61N 130

US Classification:

604 20, 604501, 607149, 607150

Abstract:

An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individuals finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individuals finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individuals finger. The second electrode is in electrical contact with the power source. Upon application of the first electrode over a treatment site with the medicament disposed between the first electrode and the treatment site and completion of an electrical circuit through the individuals body and said electrode, the device applies current for electrokinetically driving the medicament into the treatment site.

US Patent:

7016724, Mar 21, 2006

Filed:

Dec 1, 2003

Appl. No.:

10/724160

Inventors:

Julian L. Henley - New Haven CT, US
Kuo Wei Chang - Waltham MA, US
Joseph Potter - Oak Bluffs MA, US
Dennis I. Goldberg - South Brookline MA, US

Assignee:

Transport Pharmaceuticals, Inc. - West Conshohocken PA

International Classification:

A61N 1/30

US Classification:

604 20, 604501

Abstract:

An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual's finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individual's finger. The second electrode is in electrical contact with the power source. Upon application of the first electrode over a treatment site with the medicament disposed between the first electrode and the treatment site and completion of an electrical circuit through the individual's body and said electrode, the device applies current for electrokinetically driving the medicament into the treatment site.

US Patent:

7069073, Jun 27, 2006

Filed:

Mar 24, 2004

Appl. No.:

10/807295

Inventors:

Julian L. Henley - New Haven CT, US
Kuo Wei Chang - Waltham MA, US
Joseph Potter - Oak Bluffs MA, US
Dennis I. Goldberg - Boston MA, US
Christopher H. Porter - Woodinville WA, US
V. Lorenzo Porcelli - Ossining NY, US

Assignee:

BioPhoretic Therapeutic Systems, LLC - Framingham MA

International Classification:

A61N 1/30

US Classification:

604 20, 604 22, 604501, 601 1

Abstract:

An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site. In another form, the applicator is self-contained, having a power supply, a first electrode overlying a pad and a ground electrode from the opposite side from the pad whereby the individual presses the pad against the treatment site to complete the electrical circuit and electrokinetically drive the medicament into the treatment site.

US Patent:

7127285, Oct 24, 2006

Filed:

Feb 7, 2003

Appl. No.:

10/359559

Inventors:

Julian L. Henley - New Haven CT, US
Kuo Wei Chang - Waltham MA, US
Joseph Potter - Oak Bluffs MA, US
Dennis I. Goldberg - South Brookline MA, US
James Derouin - Taunton MA, US

Assignee:

Transport Pharmaceuticals Inc. - West Conshohoken PA

International Classification:

A61N 1/30

US Classification:

604 20, 604501, 607148

Abstract:

A system for delivering a substance into a body at a treatment site that includes an alternating current source and a plurality of electrodes. Circuitry is connected between the alternating current source and the electrodes for supplying current to the electrodes when the electrodes are in electrical contact with said body so that a uni-directional current flow for delivering the substance into the body is maintained at the treatment site and a bi-directional current flow is maintained throughout the body. At least one of the electrodes is divided into sub-electrodes to, for example, reduce hazards associated with current concentration. These and other systems and methods are adaptable for large treatment areas and/or use a convenient and low-cost arrangement of electronics.

US Patent:

8328788, Dec 11, 2012

Filed:

May 11, 2011

Appl. No.:

13/105630

Inventors:

Julian L. Henley - New Haven CT, US
Kuo Wei Chang - Waltham MA, US
Joseph Potter - Oak Bluffs MA, US
Dennis I. Goldberg - South Brookline MA, US
James Derouin - Taunton MA, US

Assignee:

Nitric Biotherapeutics, Inc. - Bristol PA

International Classification:

A61N 1/30

US Classification:

604501, 604 20

Abstract:

A method for delivering a substance to an infected nail of an individual is described. The method includes the step of applying a device to at least one infected nail of an individual, where the device includes at least one active electrode and at least one counter electrode, where the at least one counter electrode is in contact with the individual, and where the device is connected to at least one power source. The method also includes the steps of disposing a medicament between the at least one active electrode and the at least one infected nail, applying a salt solution to the at least one infected nail, and providing an electrical current from the power source to the at least one active electrode to facilitate delivery of the medicament into the region of the at least one infected nail.

US Patent:

8352024, Jan 8, 2013

Filed:

Mar 13, 2006

Appl. No.:

11/373301

Inventors:

Julian L. Henley - New Haven CT, US
Kuo Wei Chang - Waltham MA, US
Joseph Potter - Oak Bluffs MA, US
Dennis I. Goldberg - South Brookline MA, US
James Derouin - Taunton MA, US

Assignee:

Nitric Biotherapeutics, Inc. - Bristol PA

International Classification:

A61N 1/30

US Classification:

604 20

Abstract:

An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual's finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individual's finger. The second electrode is in electrical contact with the power source. Upon application of the first electrode over a treatment site with the medicament disposed between the first electrode and the treatment site and completion of an electrical circuit through the individual's body and said electrode, the device applies current for electrokinetically driving the medicament into the treatment site.