Joseph E Rabinowitz
age ~63
from Philadelphia, PA
- Also known as:
-
- Joseph Elias Rabinowitz
- Joseph Dorothy Rabinowitz
- Joseph Elias Rabinowit
- Joseph E Rabinowit
- Joseph Elias Y
- Phone and address:
- 611 N 6Th St, Philadelphia, PA 19123
Joseph Rabinowitz Phones & Addresses
- 611 N 6Th St, Philadelphia, PA 19123
- Cary, NC
- Carrboro, NC
- Chapel Hill, NC
- Elkins Park, PA
- Hillsborough, NC
- Secane, PA
- Swarthmore, PA
- 8300 Roberts Rd, Elkins Park, PA 19027
Us Patents
-
Virus Vectors And Methods Of Making And Administering The Same
view source -
US Patent:7172893, Feb 6, 2007
-
Filed:Jul 26, 2002
-
Appl. No.:10/205942
-
Inventors:Joseph E. Rabinowitz - Carrboro NC, US
Richard Jude Samulski - Chapel Hill NC, US
Weidong Xiao - Jenkintown PA, US -
Assignee:University of North Carolina at Chapel Hill - Chapel Hill NC
-
International Classification:C12N 7/00
C12N 7/02
C12N 15/74
C12Q 1/70
A01N 63/00 -
US Classification:4352351, 435 5, 435239, 435471, 424 931
-
Abstract:The present invention provides genetically-engineered parvovirus capsids and viruses designed to introduce a heterologous gene into a target cell. The parvoviruses of the invention provide a repertoire of vectors with altered antigenic properties, packaging capabilities, and/or cellular tropisms as compared with current AAV vectors.
-
Methods And Compounds For Controlled Release Of Recombinant Parvovirus Vectors
view source -
US Patent:7201898, Apr 10, 2007
-
Filed:Jun 1, 2001
-
Appl. No.:10/276501
-
Inventors:Paul E. Monahan - Chapel Hill NC, US
Richard Jude Samulski - Chapel Hill NC, US
Joseph E. Rabinowitz - Carrboro NC, US -
Assignee:The University of North Carolina at Chapel Hill - Chapel Hill NC
-
International Classification:A61K 48/00
A61F 2/00 -
US Classification:424 932, 424423
-
Abstract:The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i. e. , sutures, surgically implantable materials, grafts, and the like).
-
Chimeric Vectors
view source -
US Patent:7892809, Feb 22, 2011
-
Filed:Dec 15, 2005
-
Appl. No.:11/793430
-
Inventors:Dawn E. Bowles - Durham NC, US
Chengwen Li - Chapel Hill NC, US
Joseph E. Rabinowitz - Secane PA, US
Josh Grieger - Chapel Hill NC, US
Richard Jude Samulski - Chapel Hill NC, US -
Assignee:The University of North Carolina at Chapel Hill - Chapel Hill NC
The University of Florida Research Foundation - Gainesville FL -
International Classification:C12N 7/01
-
US Classification:4352351, 4353201, 536 245
-
Abstract:The present invention is based, in part, on the discovery that parvovirus (including AAV) capsids can be engineered to incorporate small, selective regions from other parvoviruses that confer desirable properties. The inventors have discovered that in some cases as little as a single amino acid insertion or substitution from a first parvovirus (e. g. , an AAV) into the capsid structure of another parvovirus (e. g. , an AAV) to create a chimeric parvovirus is sufficient to confer one or more of the desirable properties of the first parvovirus to the resulting chimeric parvovirus and/or to confer a property that is not exhibited by the first parvovirus or is present to a lesser extent.
-
Methods And Compounds For Controlled Release Of Recombinant Parvovirus Vectors
view source -
US Patent:7923436, Apr 12, 2011
-
Filed:Apr 5, 2007
-
Appl. No.:11/697194
-
Inventors:Paul E. Monahan - Chapel Hill NC, US
Richard Jude Samulski - Chapel Hill NC, US
Joseph E. Rabinowitz - Carrboro NC, US -
Assignee:University of North Carolina - Chapel Hill - Chapel Hill NC
-
International Classification:A61K 48/00
A61K 39/23 -
US Classification:514 44R, 4242331
-
Abstract:The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i. e. , sutures, surgically implantable materials, grafts, and the like).
-
Tissue Specific Gene Therapy Treatment
view source -
US Patent:8383601, Feb 26, 2013
-
Filed:Oct 30, 2007
-
Appl. No.:12/447558
-
Inventors:Walter J. Koch - Broomall PA, US
Patrick Most - Philadelphia PA, US
Sven T. Pleger - Heidelberg, DE
Joseph E. Rabinowitz - Elkins Park PA, US -
Assignee:Thomas Jefferson University - Philadelphia PA
-
International Classification:A61K 48/00
C12N 15/11
C12N 5/00 -
US Classification:514 44, 536 231, 435325
-
Abstract:The invention provides nucleic acid segments, compositions and methods for the treatment of heart failure, vascular dysfunction, endothelial dysfunction, diabetes, [Ca]i regulation and NO synthase dysfunction. Adeno-associated and adenovirus are used as gene delivery vectors for the nucleic acid segments to product long term over-expression of S100A1, a small calcium sensing protein associated with the disclosed ailments and dysfunctions.
-
Virus Vectors And Methods Of Making And Administering The Same
view source -
US Patent:20060188483, Aug 24, 2006
-
Filed:Apr 28, 2006
-
Appl. No.:11/413819
-
Inventors:Joseph Rabinowitz - Carrboro NC, US
Richard Samulski - Chapel Hill NC, US
Weidong Xiao - Jenkintown PA, US -
International Classification:A61K 48/00
C12N 15/861
C12N 7/00 -
US Classification:424093200, 435456000, 435235100
-
Abstract:The present invention provides genetically-engineered parvovirus capsids and viruses designed to introduce a heterologous gene into a target cell. The parvoviruses of the invention provide a repertoire of vectors with altered antigenic properties, packaging capabilities, and/or cellular tropisms as compared with current AAV vectors.
-
Virus Vectors And Methods Of Making And Administering The Same
view source -
US Patent:20060188484, Aug 24, 2006
-
Filed:Apr 28, 2006
-
Appl. No.:11/414319
-
Inventors:Joseph Rabinowitz - Carrboro NC, US
Richard Samulski - Chapel Hill NC, US
Weidong Xiao - Jenkintown PA, US -
International Classification:A61K 48/00
C12N 15/861
C12N 7/00 -
US Classification:424093200, 435235100, 435456000
-
Abstract:The present invention provides genetically-engineered capsids and viruses designed to introduce a heterologous gene into a target cell. The of the invention provide a repertoire of vectors with altered antigenic properties, packaging capabilities, and/or cellular tropisms as compared with current AAV vectors.
-
Chimeric Vectors
view source -
US Patent:20110104119, May 5, 2011
-
Filed:Jan 3, 2011
-
Appl. No.:12/983547
-
Inventors:Dawn E. Bowles - Durham NC, US
Chengwen Li - Chapel Hill NC, US
Joseph E. Rabinowitz - Secane PA, US
Josh Grieger - Chapel Hill NC, US
Richard Jude Samulski - Chapel Hill NC, US -
International Classification:A61K 35/76
C12N 5/00
A61P 21/00
A61P 3/10
A61P 9/00
A61P 35/00
A61P 27/02 -
US Classification:424 932, 435325
-
Abstract:The present invention is based, in part, on the discovery that parvovirus (including AAV) capsids can be engineered to incorporate small, selective regions from other parvoviruses that confer desirable properties. The inventors have discovered that in some cases as little as a single amino acid insertion or substitution from a first parvovirus (e.g., an AAV) into the capsid structure of another parvovirus (e.g., an AAV) to create a chimeric parvovirus is sufficient to confer one or more of the desirable properties of the first parvovirus to the resulting chimeric parvovirus and/or to confer a property that is not exhibited by the first parvovirus or is present to a lesser extent.
Resumes
Senior Director Capsid Development
view sourceLocation:
611 north 6Th St, Philadelphia, PA 19147
Industry:
Research
Work:
Thomas Jefferson University Aug 2004 - Feb 2012
Assistant Professor
University of North Carolina at Chapel Hill 1999 - 2004
Research Associate
Assistant Professor
University of North Carolina at Chapel Hill 1999 - 2004
Research Associate
Education:
Case Western Reserve University 1990 - 1995
Ph.D, Genetics
Ph.D, Genetics
Skills:
Molecular Biology
Immunohistochemistry
Cell Biology
Cell Culture
Genetics
Molecular Cloning
Animal Models
Western Blotting
Biochemistry
Immunohistochemistry
Cell Biology
Cell Culture
Genetics
Molecular Cloning
Animal Models
Western Blotting
Biochemistry
Assistant Professor At Thomas Jefferson University
view sourcePosition:
Assistant Professor at Thomas Jefferson University, Assistant Professor at Thomas Jefferson University
Location:
Greater Philadelphia Area
Industry:
Higher Education
Work:
Thomas Jefferson University
Assistant Professor
Thomas Jefferson University since 2004
Assistant Professor
Assistant Professor
Thomas Jefferson University since 2004
Assistant Professor
Education:
PhD
Medicine Doctors
Joseph H. Rabinowitz
view sourceSpecialties:
Family Medicine
Work:
Novant Health Medical GroupChair City Family Medicine
903 Randolph St STE 1, Thomasville, NC 27360
(336)4757163 (phone), (336)4751199 (fax)
903 Randolph St STE 1, Thomasville, NC 27360
(336)4757163 (phone), (336)4751199 (fax)
Languages:
English
Spanish
Spanish
Description:
Dr. Rabinowitz works in Thomasville, NC and specializes in Family Medicine. Dr. Rabinowitz is affiliated with Novant Health Forsyth Medical Center.
Isbn (Books And Publications)
Classmates
Joseph Rabinowitz, Shorew...
view sourceJoseph Rabinowitz 1994 graduating class of Shorewood High School in Shorewood, WI
Joseph Rabinowitz, Bronx,...
view sourceJoseph Rabinowitz 1968 graduating class of DeWitt Clinton High School in Bronx, NY
Joe Rabinowitz, North bay...
view sourceJoe Rabinowitz 1980 graduate of Widdifield High School in North bay, ON
Shorewood High School, Sh...
view sourceGraduates:
Cheryl Briggs (1974-1978),
Joseph Rabinowitz (1991-1994),
Brooke Wickliffe (1962-1968),
Dawn Pfeifer (1979-1983),
Maureen Barth (1956-1960)
Joseph Rabinowitz (1991-1994),
Brooke Wickliffe (1962-1968),
Dawn Pfeifer (1979-1983),
Maureen Barth (1956-1960)
Widdifield High School, N...
view sourceGraduates:
Joe Rabinowitz (1976-1980),
Mark Smith (1968-1972),
Russell Reynolds (1963-1967),
Trista Ransom (1999-2003),
Angela Knight (1979-1983)
Mark Smith (1968-1972),
Russell Reynolds (1963-1967),
Trista Ransom (1999-2003),
Angela Knight (1979-1983)
Youtube
Flickr
Googleplus
Joseph Rabinowitz
News
National Guard helicopter joins search for missing Mount Hood climber
view source- "It's very icy, especially below Crater Rock," said Reach and Treat paramedic Joseph Rabinowitz, one of the rescuers. "This is the second fall we have responded to this weekend -- fortunately, the first climber was uninjured. Climbers should exercise extreme caution while descending."
- Date: Feb 07, 2012
- Category: U.S.
- Source: Google
Joseph Rabinowitz Philad...
view sourceJoseph Rabinowitz (Philadelphia, PA)
Joseph Rabinowitz
view source
Search Names Joseph Rabin...
view sourceGet Report for Joseph E Rabinowitz from Philadelphia, PA, age ~63