Joseph E C Rogers

US Patent:

20090260458, Oct 22, 2009

Filed:

Apr 17, 2008

Appl. No.:

12/105198

Inventors:

Victor Joseph - Fremont CA, US
Joseph F. Rogers - Mountain View CA, US
Kumar Kastury - San Jose CA, US

International Classification:

G01N 1/38

US Classification:

7386401, 422100, 4353091

Abstract:

The invention is directed to systems and methods for transferring nano-quantities of fluid samples using a high throughput or ultra high throughput dispenser. Such samples may be transferred from a first location and reformatted for being transferred to a second location. The invention may transfer a predetermined volume of sample quickly and accurately.

US Patent:

20100009335, Jan 14, 2010

Filed:

Feb 7, 2007

Appl. No.:

12/278570

Inventors:

Victor Joseph - Fremont CA, US
Amjad Huda - Fremont CA, US
Joseph F. Rogers - Sunnyvale CA, US

International Classification:

C12Q 3/00
C12M 1/36

US Classification:

435 3, 4352861

Abstract:

Described herein are environmentally isolated tissue culture devices that may be used for cell culture, as well as systems including these devices and methods for using them. These devices may include control features for regulating the micro-environment within a well or wells of the device. For example, on-board features may regulate the temperature, humidity, pH, media level, media composition, CO/O/Nlevels, drug concentration, cell density, byproduct (or product) production, and mixing of materials within the chamber. Material may be added to or withdrawn from the wells of the device without opening the device. Also described herein are controllers for analyzing and controlling the micro- environment within the well. Thus, the plates described herein may be used without requiring a separate incubator, allowing cells to be analyzed (e.g., imaged) continuously, allowing real-time reactions while monitoring under a microscope for hours, days or even weeks.