Joseph R Russell

US Patent:

20220331806, Oct 20, 2022

Filed:

Jun 24, 2022

Appl. No.:

17/808563

Inventors:

- Kansas City MO, US
Joseph A. Russell - Arlington VA, US
Jacob R. Aspinwall - Palm Bay FL, US

International Classification:

B01L 9/02
C12Q 1/686
A45F 4/02
A45F 3/04
A45C 5/04
B01L 1/00
A45C 5/14
A45C 7/00

Abstract:

A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.

US Patent:

20220291212, Sep 15, 2022

Filed:

May 23, 2022

Appl. No.:

17/750987

Inventors:

- Baltimore MD, US
Joseph Patrick Russell - Odenton MD, US

International Classification:

G01N 33/543

Abstract:

The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the first probe is coupled to a detectable piece, the target is coupled to the first probe and the second probe, and the second probe is coupled to a solid support. Specific binding of the detectable piece to the target analyte can be distinguished from non-specific binding of the detectable piece by measuring the number of detectable pieces that leave their initial location after exposure to a disruptor that uncouples the detectable piece from the solid support.

US Patent:

20190361016, Nov 28, 2019

Filed:

May 23, 2019

Appl. No.:

16/420231

Inventors:

- Baltimore MD, US
Joseph P. Russell - Odenton MD, US

International Classification:

G01N 33/543

Abstract:

The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the first probe is coupled to a detectable piece, the target is coupled to the first probe and the second probe, and the second probe is coupled to a solid support. Specific binding of the detectable piece to the target analyte can be distinguished from non-specific binding of the detectable piece by measuring the number of detectable pieces that leave their initial location after exposure to a disruptor that uncouples the detectable piece from the solid support.

US Patent:

20190076844, Mar 14, 2019

Filed:

Nov 9, 2018

Appl. No.:

16/185178

Inventors:

- Kansas City MO, US
Joseph A. Russell - Arlington VA, US
Jacob R. Aspinwall - Palm Bay FL, US

International Classification:

B01L 9/02
C12Q 1/686
A45F 4/02

Abstract:

A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.

US Patent:

20180193843, Jul 12, 2018

Filed:

Jan 9, 2018

Appl. No.:

15/866073

Inventors:

- Kansas City MO, US
Joseph A. Russell - Arlington VA, US
Jacob R. Aspinwall - Palm Bay FL, US

International Classification:

B01L 9/02
C12Q 1/04
B01L 7/00
C12M 1/00
B01L 3/00
C12Q 1/24
G01N 15/04
G01N 21/64
G01N 33/483
G01N 33/50
G01N 1/00
G01N 15/00

Abstract:

A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The mobile laboratory can be configured either in a single backpack configuration or in a footlocker configuration wherein both configurations include a plurality of different compartments specifically configured for holding all of the necessary equipment for successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source, a cold storage compartment for frozen and chilled critical reagents, a PCR detection system, a DNA/RNA sequencing system, a bioinformatics analysis system, a centrifuge, and a deployable workbench area which provides a stable workstation when either the backpack or footlocker configuration is deployed.