Judith Wolfe Laney

US Patent:

62386557, May 29, 2001

Filed:

Dec 15, 1997

Appl. No.:

8/990989

Inventors:

Charles W. Slife - New Market MD
Judith Wolfe Laney - Silver Spring MD
Virginia Streusand Goldman - Potomac MD

Assignee:

The Gillette Company - Boston MA

International Classification:

A61K 732
A61K 706
A61K 715
A61K 746

US Classification:

424 65

Abstract:

Disclosed are. alpha. -amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, threonine amides, glycine amides, serine amides, and alanine amides can be used in the invention. Such. alpha. -amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the. alpha. -amides of L-amino acids by bacteria in axillae. The. alpha. -amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.

US Patent:

56485131, Jul 15, 1997

Filed:

Nov 22, 1995

Appl. No.:

8/562086

Inventors:

Judith Wolfe Laney - Silver Spring MD

International Classification:

C07C22960
C07C 6984
C07C 6968

US Classification:

560 49

Abstract:

The invention relates to a method of suppressing human body malodor by utilizing a deodorant composition containing a competitive substrate for the enzymatic creation of axillary body malodor. The compound is present in a dermatologically acceptable vehicle, and in an amount effective to reduce the conversion of malodor producing precursor. The present invention also relates to novel O-acylated serine compounds and method for the production thereof.

US Patent:

59321989, Aug 3, 1999

Filed:

Dec 15, 1997

Appl. No.:

8/990988

Inventors:

Virginia Streusand Goldman - Potomac MD
Judith Wolfe Laney - Silver Spring MD
Charles W. Slife - New Market MD

Assignee:

The Gillette Company - Boston MA

International Classification:

A61K 732
A61K 706
A61K 715
A61K 700

US Classification:

424 65

Abstract:

Disclosed are. alpha. -amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, glutamine and asparagine amides can be used in the invention. Such. alpha. -amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the. alpha. -amides of L-amino acids by bacteria in axillae. The. alpha. -amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.

US Patent:

54319048, Jul 11, 1995

Filed:

Sep 9, 1993

Appl. No.:

8/118188

Inventors:

Judith W. Laney - Silver Spring MD

Assignee:

The Gillette Company - Boston MA

International Classification:

A61K 732
A61K 734
A61K 736

US Classification:

424 65

Abstract:

The invention relates to a method of suppressing human body malodor by utilizing a deodorant composition containing a competitive substrate for the enzymatic creation of axillary body malodor. The compound is present in a dermatologically acceptable vehicle, and in an amount effective to reduce the conversion of malodor producing precursor. The present invention also relates to novel O-acylated serine compounds and method for the production thereof.

US Patent:

58008047, Sep 1, 1998

Filed:

Mar 18, 1996

Appl. No.:

8/617424

Inventors:

Judith Wolfe Laney - Silver Spring MD

Assignee:

The Gillette Company - Boston MA

International Classification:

A61K 732
A61K 700

US Classification:

424 65

Abstract:

The invention relates to a method for reducing malodor, preferably by generating a pleasant odor, in the axilla utilizing a deodorant composition containing a competitive substrate for the malodor producing enzyme. Upon cleavage by the malodor producing enzyme, the compounds of the present invention result in byproducts which produce either a neutral or a pleasant odor. The compound is present in a dermatologically acceptable vehicle, and in an amount effective to produce either a neutral or a pleasant odor. The present invention also relates to novel O-acylated serine and threonine compounds and method for the production thereof.