Julia K Wang

US Patent:

53316690, Jul 19, 1994

Filed:

May 6, 1992

Appl. No.:

7/879953

Inventors:

James H. Wang - Mission Viejo CA
Julia W. Wang - Mission Viejo CA

Assignee:

Ologic Corporation - Costa Mesa CA

International Classification:

H04L 700
H04L 2536
H04L 2540
H03K 513

US Classification:

375118

Abstract:

An improved pulse converter for converting a stream of asynchronous input pulses of undetermined duration into a stream of synchronous output pulses of standard duration. The input pulses may occur in any phase or frequency relationship to the reference with the limitation that the input pulses must not occur more frequently than one period of a reference clock plus one synchronizer input hold time and one synchronizer setup time. Additionally, the input pulses must be at least as wide as required to set an input flip-flop. The inventive asynchronous pulse converter requires only two flip-flops, a synchronizer, and a single Exclusive-OR gate, and a single reference clock.

US Patent:

20190307885, Oct 10, 2019

Filed:

Apr 4, 2019

Appl. No.:

16/375285

Inventors:

- Boston MA, US
Julia Wang - Forest Hills NY, US
Derek G. van der Poll - Medford MA, US
Dominick J. Blasioli - Chelmsford MA, US

International Classification:

A61K 47/22
A61K 47/14
A61K 9/00
A61K 9/06
A61K 9/16
A61K 9/51

Abstract:

Gels are formed based on generally recognized as safe (GRAS) low molecular weight amphiphilic molecules in a self-assembly process. Therapeutic or prophylactic agents, such as biological macromolecules, are loaded without exposure to temperatures and/or organic solvents which can degrade or destroy the biologic agents and/or their activity. The resulting self-assembled gel composition contains microstructures having pores and aqueous domains at their interior, rendering them permeable to hydrophilic and hydrophobic molecules. This permeability allows sequestration of the biological macromolecules. Once sequestered, the electrostatic, hydrophobic-hydrophobic etc. interactions between the biological macromolecules and the amphiphilic gelators keep the labile payload encapsulated with high stability until the microstructures are degraded.