Kevin J. Duffy - Collegeville PA, US Julian Jenkins - Collegeville PA, US Juan I. Luengo - Collegeville PA, US Sophie Visonneau - Thousand Oaks PA, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA Glaxo Group Limited - Greenford
International Classification:
C07D 231/46 A61K 31/4152 A61K 31/655
US Classification:
514150, 514404, 534792, 5483674
Abstract:
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Kevin J. Duffy - Collegeville PA, US Juan I. Luengo - Collegeville PA, US Stephen G. Miller - San Diego CA, US Julian Jenkins - Collegeville PA, US Alan T. Price - Collegeville PA, US Antony N. Shaw - Collegeville PA, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA Ligand Pharmaceutical - San Diego CA
International Classification:
A61K 31/427 A61K 31/4709 A61K 31/4152
US Classification:
514369, 514310, 514404
Abstract:
Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected substituted thiosemicarbazone derivative.
Kevin J. Duffy - Collegeville PA, US Julian Jenkins - Collegeville PA, US Juan Luengo - Collegeville PA, US Alan T. Price - Collegeville PA, US Antony N. Shaw - Collegeville PA, US Sophie Visonneau - San Diego PA, US Kenneth Wiggall - Collegeville PA, US
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Kevin J. Duffy - Collegeville PA, US Julian Jenkins - Collegeville PA, US Juan I. Luengo - Collegeville PA, US Sophie Visonneau - Collegeville PA, US
Assignee:
SmithKline Beecham Corp. - Philadelphia PA
International Classification:
C07D 231/46 A61K 31/4152 A61K 31/655
US Classification:
514150, 514404, 534792, 5483674
Abstract:
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Kevin J. Duffy - Collegeville PA, US Julian Jenkins - Collegeville PA, US Juan I. Luengo - Collegeville PA, US Sophie Visonneau - Collegeville PA, US
Assignee:
SmithKline Beecham Corp. - Philadelphia PA
International Classification:
A61K 31/655 A61K 31/4152 C07C 245/10 C07D 231/46
US Classification:
514150
Abstract:
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Kevin J. Duffy - Collegeville PA, US Julian Jenkins - Collegeville PA, US Juan I. Luengo - Collegeville PA, US
Assignee:
GlaxoSmithKline, LLC - Philadelphia PA
International Classification:
A61K 31/655 A61P 7/00 C07D 231/38
US Classification:
514150
Abstract:
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
Methods Of Administration Of Thrombopoietin Agonist Compounds
The embodiments provide methods of administering a high dose or a loading dose of a TPO modulator to a subject. The embodiments further provide methods of treating thrombocytopenia and/or neutropenia in a subject. Additionally, the embodiments further provide methods of increasing platelet production and/or enhancing the number of peripheral blood stem cells in a subject.
Isbn (Books And Publications)
Christian Pacifism Confronts German Nationalism: The Ecumenical Movement and the Cause of Peace in Germany, 1914-1933
Our Lady of Consolation School Philadelphia PA 1988-1995, Swenson Arts And Technology Center Philadelphia PA 1996-2000, Swenson High School Philadelphia PA 1996-2000, Swenson Skills Center Philadelphia PA 1996-2000
Julian has been capturing images for twenty-two years and was educated in the field of photojournalism while living in Los Angeles where he worked for various newspapers and publications in the beach ...
Julian Jenkins
Julian Jenkins
Julian Jenkins
Julian Jenkins
Julian Jenkins
Julian Jenkins
Julian Jenkins
Flickr
News
Alabama senator gets free hotel for promise to renovate, maintain
superintendent and two-time candidate for governor -- built the structure in 1888 as his home on a hill. Nearly 100 years later, Anniston developer Earlon McWhorter and architect Julian Jenkins restored the home and in 1984 the National Park Service listed it on the National Register of Historic Places.
Date: Jun 22, 2015
Category: Business
Source: Google
White House: Fathers need help to stay at home, too
Julian Jenkins, a working father, said he grew up in a housing project in North Philadelphia without his father. When he had his own children, he decided to work the night shift at his job in order to have some day time with his three, now-adult daughters.