Shohei Koide - Chicago IL, US Stephen Dewhurst - Rochester NY, US Akiko Koide - Chicago IL, US Julie Richards - Rochester NY, US Michelle Miller - Rochester NY, US
International Classification:
C07K 16/28
US Classification:
530388220
Abstract:
The present invention relates to a polypeptide monobody which includes a modified acid sequence and renders the polypeptide monobody able to bind selectively to αvβ3 integrin. Fusion proteins and conjugates which include the polypeptide monobody, as well as compositions containing the polypeptide monobody, fusion proteins, or conjugates are also disclosed. Uses thereof include: treating or preventing an αvβ3 integrin-mediated disease or disorder, inhibiting αvβ3 integrin activity, treating a cancerous or precancerous condition, imaging tissues using positron emission tomography or magnetic resonance imaging, assessing the metastatic characteristics of a tumor, and delivering DNA to a cell.
Phillips University - Elementary Education, Washburn University - Elementary Education, Webster University - Curriculum and Instruction, Pittsburg State University - Educational Technology, Pittsburg State University - School Administration
Julie Richards
About:
I work in education and enjoy sarcasm and irony, which goes a long way in my job. Married with 2 kids and a huge labrador called Jessie, who is a reflection of me, apparently. I guess the similarity i...
Tagline:
Philosophy starts in the playground
Bragging Rights:
Worked in media, education, retail and a mad house (my home)
Julie Richards
Julie Richards
Julie Richards
Tagline:
I'm simple...I love my hubby, kids, family, friends and chocolate!