Jun Yang

US Patent:

6641708, Nov 4, 2003

Filed:

Aug 23, 1999

Appl. No.:

09/378874

Inventors:

Frederick F. Becker - Houston TX
Peter R. C. Gascoyne - Belaire TX
Ying Huang - San Diego CA
Xiao-Bo Wang - San Diego CA
Jun Yang - Houston TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 2726

US Classification:

204547, 204643

Abstract:

Methods and apparatus for discriminating matter in a chamber having an inlet port and an outlet port utilizing dielectrophoresis and field flow fractionation. A carrier medium is introduced into the inlet port and is directed from the inlet port to the outlet port according to a velocity profile. A programmed voltage signal is applied to an electrode element coupled to the chamber to form a dielectrophoretic force on the matter. The dielectrophoretic force is balanced with a gravitational force to displace the matter to positions within said velocity profile in the carrier medium to discriminate the matter. A chamber having a top and bottom outlet port may be utilized to withdraw a first portion of a carrier medium from the top outlet port at a first, controllable fluid flow rate and to withdraw a second portion of the carrier medium from the bottom outlet port at a second, controllable fluid flow rate.

US Patent:

7316907, Jan 8, 2008

Filed:

Sep 10, 2004

Appl. No.:

10/938387

Inventors:

Dihua Yu - Houston TX, US
Jun Yao - Chestnut Hill MA, US
Christopher L. Neal - Houston TX, US
Wentao Yang - Shanghai, CN
Xiaoyan Zhou - Shanghai, CN
Raphael E. Pollock - Houston TX, US
Mien-Chie Hung - Houston TX, US
Jun Yang - Houston TX, US
Ping Li - Houston TX, US
Nina T. Nguyen - Houston TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 33/53
G01N 33/574

US Classification:

435 71, 435 723

Abstract:

Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.

US Patent:

7709205, May 4, 2010

Filed:

Dec 4, 2007

Appl. No.:

11/950264

Inventors:

Dihua Yu - Houston TX, US
Jun Yao - Chestnut Hill MA, US
Christopher L. Neal - Houston TX, US
Wentao Yang - Shanghai, CN
Xiaoyan Zhou - Shanghai, CN
Raphael E. Pollock - Houston TX, US
Mien-Chie Hung - Houston TX, US
Jun Yang - Houston TX, US
Ping Li - Houston TX, US
Nina T. Nguyen - Houston TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.

US Patent:

8146189, Apr 3, 2012

Filed:

Nov 24, 2008

Appl. No.:

12/276895

Inventors:

Jun Yang - Drexel Hill PA, US
Jing Feng - Drexel Hill PA, US

International Classification:

A47B 7/02

US Classification:

5618, 5616, 600415, 606245

Abstract:

A patient alignment device includes a table and a rotatable member positioned to rotate relative to the table. The rotatable member may be a head-support plate or a board which supports substantially all of a patient's body. A motor moves the board or plate so as to align the patient's body, or a part of the body, in a desired direction. The board may be formed in two segments, the segments being selectively connectable to each other, the segments also being selectively connectable to the table by pins, at various possible pivot points. Positioning of the pins determines the mode of rotation of the board. The invention allows an operator to align the patient's body with precision, by remote control, and without interrupting the medical procedure.

US Patent:

20040011651, Jan 22, 2004

Filed:

May 13, 2003

Appl. No.:

10/436647

Inventors:

Frederick Becker - Houston TX, US
Peter Gascoyne - Belaire TX, US
Ying Huang - San Diego CA, US
Xiaobo Wang - San Diego CA, US
Jun Yang - Houston TX, US

Assignee:

Board of Regents, The University of Texas System

International Classification:

G01N027/27

US Classification:

204/547000, 204/643000

Abstract:

Methods and apparatus for discriminating matter in a chamber having an inlet port and an outlet port utilizing dielectrophoresis and field flow fractionation. A carrier medium is introduced into the inlet port and is directed from the inlet port to the outlet port according to a velocity profile. A programmed voltage signal is applied to an electrode element coupled to the chamber to form a dielectrophoretic force on the matter. The dielectrophoretic force is balanced with a gravitational force to displace the matter to positions within said velocity profile in the carrier medium to discriminate the matter. A chamber having a top and bottom outlet port may be utilized to withdraw a first portion of a carrier medium from the top outlet port at a first, controllable fluid flow rate and to withdraw a second portion of the carrier medium from the bottom outlet port at a second, controllable fluid flow rate.

US Patent:

20120159713, Jun 28, 2012

Filed:

Mar 7, 2012

Appl. No.:

13/413848

Inventors:

Jun Yang - Garnet Valley PA, US
Jing Feng - Drexel Hill PA, US

International Classification:

A61G 7/07
A61G 13/02
A61G 7/002

US Classification:

5622, 5600

Abstract:

A patient alignment device includes a table and a rotatable member positioned to rotate relative to the table. The rotatable member may be a head-support plate or a board which supports substantially all of a patient's body. A motor moves the board or plate so as to align the patient's body, or a part of the body, in a desired direction. The board may be formed in two segments, the segments being selectively connectable to each other, the segments also being selectively connectable to the table by pins, at various possible pivot points. Positioning of the pins determines the mode of rotation of the board. The invention allows an operator to align the patient's body with precision, by remote control, and without interrupting the medical procedure.

US Patent:

20210111530, Apr 15, 2021

Filed:

Oct 9, 2019

Appl. No.:

16/596797

Inventors:

- Lisle IL, US
LIFU GONG - Lisle IL, US
JUN YANG - Lisle IL, US

Assignee:

Molex, LLC - Lisle IL

International Classification:

H01S 3/067

Abstract:

An amplified spontaneous emission (ASE) light source and a method for using the ASE light source are provided. The ASE light source may include a seed stage light source for providing a light beam to be amplified. The apparatus may include a tunable element coupled to the seed stage light source configured for filtering a portion of the light beam from the seed stage light source. The apparatus may include a loopback circuit coupled to the tunable element, the loopback circuit comprising a booster stage element for amplifying light from the tunable element.