Jun Lin Yang

Address:

19143 Clevera Walk Ln, Houston, TX 77084

Phone:

(713)8945061

VIN:

2T1BU4EE5CC812865

Make:

TOYOTA

Model:

COROLLA

Year:

2012

Address:

11711 Memorial Dr APT 159, Houston, TX 77024

VIN:

5NPET46C57H264348

Make:

HYUNDAI

Model:

SONATA

Year:

2007

US Patent:

6641708, Nov 4, 2003

Filed:

Aug 23, 1999

Appl. No.:

09/378874

Inventors:

Frederick F. Becker - Houston TX
Peter R. C. Gascoyne - Belaire TX
Ying Huang - San Diego CA
Xiao-Bo Wang - San Diego CA
Jun Yang - Houston TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 2726

US Classification:

204547, 204643

Abstract:

Methods and apparatus for discriminating matter in a chamber having an inlet port and an outlet port utilizing dielectrophoresis and field flow fractionation. A carrier medium is introduced into the inlet port and is directed from the inlet port to the outlet port according to a velocity profile. A programmed voltage signal is applied to an electrode element coupled to the chamber to form a dielectrophoretic force on the matter. The dielectrophoretic force is balanced with a gravitational force to displace the matter to positions within said velocity profile in the carrier medium to discriminate the matter. A chamber having a top and bottom outlet port may be utilized to withdraw a first portion of a carrier medium from the top outlet port at a first, controllable fluid flow rate and to withdraw a second portion of the carrier medium from the bottom outlet port at a second, controllable fluid flow rate.

US Patent:

7316907, Jan 8, 2008

Filed:

Sep 10, 2004

Appl. No.:

10/938387

Inventors:

Dihua Yu - Houston TX, US
Jun Yao - Chestnut Hill MA, US
Christopher L. Neal - Houston TX, US
Wentao Yang - Shanghai, CN
Xiaoyan Zhou - Shanghai, CN
Raphael E. Pollock - Houston TX, US
Mien-Chie Hung - Houston TX, US
Jun Yang - Houston TX, US
Ping Li - Houston TX, US
Nina T. Nguyen - Houston TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 33/53
G01N 33/574

US Classification:

435 71, 435 723

Abstract:

Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.

US Patent:

7709205, May 4, 2010

Filed:

Dec 4, 2007

Appl. No.:

11/950264

Inventors:

Dihua Yu - Houston TX, US
Jun Yao - Chestnut Hill MA, US
Christopher L. Neal - Houston TX, US
Wentao Yang - Shanghai, CN
Xiaoyan Zhou - Shanghai, CN
Raphael E. Pollock - Houston TX, US
Mien-Chie Hung - Houston TX, US
Jun Yang - Houston TX, US
Ping Li - Houston TX, US
Nina T. Nguyen - Houston TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.

US Patent:

20040011651, Jan 22, 2004

Filed:

May 13, 2003

Appl. No.:

10/436647

Inventors:

Frederick Becker - Houston TX, US
Peter Gascoyne - Belaire TX, US
Ying Huang - San Diego CA, US
Xiaobo Wang - San Diego CA, US
Jun Yang - Houston TX, US

Assignee:

Board of Regents, The University of Texas System

International Classification:

G01N027/27

US Classification:

204/547000, 204/643000

Abstract:

Methods and apparatus for discriminating matter in a chamber having an inlet port and an outlet port utilizing dielectrophoresis and field flow fractionation. A carrier medium is introduced into the inlet port and is directed from the inlet port to the outlet port according to a velocity profile. A programmed voltage signal is applied to an electrode element coupled to the chamber to form a dielectrophoretic force on the matter. The dielectrophoretic force is balanced with a gravitational force to displace the matter to positions within said velocity profile in the carrier medium to discriminate the matter. A chamber having a top and bottom outlet port may be utilized to withdraw a first portion of a carrier medium from the top outlet port at a first, controllable fluid flow rate and to withdraw a second portion of the carrier medium from the bottom outlet port at a second, controllable fluid flow rate.