Kenneth H. Grabstein - Mercer Island WA, US Dirk M. Anderson - Seattle WA, US June R. Eisenman - Seattle WA, US Victor Fung - Redmond WA, US Charles Rauch - Bainbridge Island WA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 48/00 C12N 15/24
US Classification:
514 44, 536 243, 536 2431
Abstract:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
Method Of Treating Cancer By Administering An Epithelum-Derived T-Cell Factor
Kenneth H. Grabstein - Mercer Island WA, US Dirk M. Anderson - Seattle WA, US June R. Eisenman - Seattle WA, US Victor Fung - Redmond WA, US Charles Rauch - Bainbridge Island WA, US
Assignee:
Immunex Corporation - Seattle WA
International Classification:
A61K 38/19 A61K 38/20
US Classification:
424 852, 514 2, 514 8, 514 12
Abstract:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
Kenneth H. Grabstein - Mercer Island WA Dirk M. Anderson - Seattle WA June R. Eisenman - Seattle WA Victor Fung - Redmond WA Charles Rauch - Bainbridge Island WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
C07K 1624
US Classification:
5303879
Abstract:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
Kenneth H. Grabstein - Mercer Island WA Dirk M. Anderson - Seattle WA June R. Eisenman - Seattle WA Victor Fung - Redmond WA Charles Rauch - Bainbridge Island WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
A61K 3820 C07K 1454
US Classification:
530351
Abstract:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
Kenneth H. Grabstein - Mercer Island WA Dirk M. Anderson - Seattle WA June R. Eisenman - Seattle WA Victor Fung - Redmond WA Charles Rauch - Bainbridge Island WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
C07K 1624 A61K 39395 C12N 512
US Classification:
53038823
Abstract:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
Method For Treating Or Preventing Gastrointestinal Disease With Epithelium-Derived T-Cell Factor
Kenneth H. Grabstein - Mercer Island WA Dirk M. Anderson - Seattle WA June R. Eisenman - Seattle WA Victor Fung - Redmond WA Charles Rauch - Bainbridge Island WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
A61K 3820 C12N 1524 C07K 1454
US Classification:
424 852
Abstract:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
Kenneth Grabstein - Mercer Island WA Dirk Anderson - Seattle WA June Eisenman - Seattle WA Victor Fung - Redmond WA Charles Rauch - Bainbridge Island WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
C12P 2106 C12N 1524 C12N 510 C07K 1454
US Classification:
435 6951
Abstract:
There is disclosed a mammalian epithelium-derived T-cell factor (EFT) polypeptide, derivatives thereof, DNA sequences, recombinant DNA molecules and transformed host cells that produce ETF polypeptides. More particularly, this invention provides isolated mammalian ETF polypeptides and derivatives thereof that regulate events in T-lymphocyte proliferation.
Method Of Treatment With Epithelium Derived T-Cell Factor
Kenneth H. Grabstein - Mercer Island WA Dirk M. Anderson - Seattle WA June R. Eisenman - Seattle WA Victor Fung - Redmond WA Charles Rauch - Bainbridge Island WA
Assignee:
Immunex Corporation - Seattle WA
International Classification:
A61K 3820 C07K 1454 C12N 1524
US Classification:
424 852
Abstract:
Nucleic acid sequences which encode biologically active EMF, expression vectors which direct the expression of ETF, ETE polypeptides, antibodies which specffically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.