- Tucson AZ, US Joerg Bredno - San Francisco CA, US Rebecca C. Bowermaster - Tucson AZ, US Srinivas Chukka - San Jose CA, US Wen-Wei Liu - Tucson AZ, US Kandavel Shanmugam - Chandler AZ, US Junming Zhu - Oro Valley AZ, US
International Classification:
G06T 7/00 G01N 33/574
Abstract:
Immune context scores are calculated for tumor tissue samples using continuous scoring functions. Feature metrics for at least one immune cell marker are calculated for a region or regions of interest, the feature metrics including at least a quantitative measure of human CD3 or total lymphocyte counts. A continuous scoring function is then applied to a feature vector including the feature metric and at least one additional metric related to an immunological biomarker, the output of which is an immune context score. The immune context score may then be plotted as a function of a diagnostic or treatment metric, such as a prognostic metric (e.g. overall survival, disease-specific survival, progression-free survival) or a predictive metric (e.g. likelihood of response to a particular treatment course). The immune context score may then be incorporated into diagnostic and/or treatment decisions.
Resumes
Senior Director Of Biostatistics And Data Management
Eisai - Woodcliff Lake, NJ since Mar 2013
Director of Biostatistics, Oncology
Agennix Nov 2010 - Feb 2013
Sr. Director of Biostatistics and Data Management
Eli Lilly and Company Nov 2009 - Oct 2010
Director of Biostatistics
ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company Jan 2008 - Nov 2009
Director of Biostatistics
GPC Biotech Feb 2007 - Jan 2008
Director of Biostatistics
Education:
Harvard University 1992 - 1995
Skills:
Clinical Trials Biostatistics Data Management Clinical Development Cro Oncology Drug Development Regulatory Submissions Gcp Pharmaceutical Industry Biotechnology Fda Lifesciences Cdisc Edc Clinical Study Design Clinical Research Clinical Data Management Sop Ind Validation Sas Programming Life Sciences Biopharmaceuticals Protocol Ctms
Oct 2010 to 2000 Senior Director of Biostatistics and Data ManagementImClone Systems LLC Bridgewater, NJ Jan 2008 to Oct 2010 Director of BiostatisticsGPC Biotech, Inc Princeton, NJ Feb 2007 to Dec 2007 Director of Biostatistics and Data ManagementBracco Diagnostics Inc Princeton, NJ Jul 2003 to Jan 2007 Associate Director, Corporate BiometricsAdvanced Biomedical Research, Inc Pennington, NJ Jan 2002 to Jun 2003 Director of Biostatistics and SAS ProgrammingFrontier Science and Technology Research Foundation Boston, MA Sep 1996 to Jan 2002 Senior Research ScientistSerOpix, Inc Woburn, MA 2000 to 2000 Sr. Statistical ConsultantHuman Development Department, the World Bank
1996 to 1999 ConsultantCenter for Population and Development Studies
Sep 1995 to Aug 1996 Joint Research FellowHuman Settlement Agenda
1996 to 1996 Consultant, Program for the HABITAT IIPeking University
Jul 1992 to Aug 1995 Associate ProfessorMinja Kim Choe, East-West Center, Program on Population Honolulu, HI 1994 to 1994 Visiting ProfessorInternational Council for Canadian Studies
1994 to 1994 Visiting scholarEast China Normal University
Jul 1989 to Jun 1992 Lecturer and Researcher
Education:
Harvard University Extension School and School of Public Health Boston, MA 1996 to 2001 Business AdministrationEast China Normal University 1989 to 1992 Ph.DEast China Normal University 1987 to 1989 Environmental System EngineeringEast China Normal University 1983 to 1987 BS in Mathematics
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zhu ang ih ren kun ming hsian jian hu
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Sports
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Dance with bowl on the head!!!!.....
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