Justin T Mohr

US Patent:

20060084820, Apr 20, 2006

Filed:

Aug 29, 2005

Appl. No.:

11/215449

Inventors:

Douglas Behenna - Elverson PA, US
Brian Stoltz - Pasadena CA, US
Justin Mohr - Pasadena CA, US
Andrew Harned - Pasadena CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

C07F 7/08
C07C 69/66

US Classification:

556437000, 560174000

Abstract:

Compounds containing a substituted or unsubstituted allyl group directly bound to a chiral carbon atom are prepared enantioselectively. Starting reactants are either chiral or achiral, and may or may not contain an attached allyloxycarbonyl group as a substituent. Chiral ligands are employed, along with transition metal catalysts. The methods of the invention are effective in providing enantioconvergent allylation of chiral molecules.