Lars Burgdorf - Frankfurt am Main, DE Melanie Schultz - Darmstadt, DE Tatjana Ross - Eschborn, DE Brian Hodous - Cambridge MA, US Justin Potnick - Acton MA, US Amanda E. Sutton - Hingham MA, US Bayard R. Huck - Sudbury MA, US
Assignee:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG - DARMSTADT
Compounds of the formula Iin which Rand Rhave the meanings indicated in Claim are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis and/or systemic lupus
Amanda E. Sutton - Hingham MA, US Nadia Brugger - Cambridge MA, US Thomas E. Richardson - Durham NC, US Harold George Vandeveer - Indianapolis IN, US Bayard R. Huck - Sudbury MA, US Ruoxi Lan - Waltham MA, US Justin Potnick - Acton MA, US
The invention provides novel substituted azaheterocyclic compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
Fused Imidazopyridines As Reversible Inhibitors Of Brutons Tyrosine Kinase (Btk)
- Darmstadt, DE Lesley LIU-BUJALSKI - Billerica MA, US Justin POTNICK - Billerica MA, US Constantin NEAGU - Billerica MA, US Shashank KULKARNI - Billerica MA, US Reinaldo JONES - Billerica MA, US Hui QIU - Billerica MA, US
International Classification:
C07D 471/04
Abstract:
The present invention relates to fused imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
Heteroaryl Compounds As Btk Inhibitors And Uses Thereof
- Darmstadt, DE Jeyaprakashnarayanan Seenisamy - Karnataka, IN Lesley Liu-Bujalski - Bedford MA, US Richard D. Caldwell - Brookline MA, US Justin Potnick - Acton MA, US Hui Qiu - Acton MA, US Constantin Neagu - Belmont MA, US Reinaldo Jones - Lowell MA, US Annie Cho Won - Somerville MA, US Andreas Goutopoulos - Boston MA, US Brian A. Sherer - Nashua NH, US Theresa L. Johnson - Salem MA, US Anna Gardberg - Arlington MA, US
International Classification:
C07D 471/04 C07D 519/00
Abstract:
Imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof are useful as BTK inhibitors.
- Darmstadt, DE Ruoxi LAN - Waltham MA, US Justin POTNICK - Acton MA, US Lizbeth Celeste DESELM - Melrose MA, US Constantin NEAGU - Belmont MA, US Xiaoling CHEN - Chestnut Hill MA, US Roch BOIVIN - North Chelmsford MA, US Theresa L. JOHNSON - Salem MA, US Andreas GOUTOPOULOS - Boston MA, US
Novel azaquinazoline carboxamide derivatives of formula (I)wherein W, W, W, W, R, R, Rand m which are defined above, are p70S6K inhibitor, and can be employed, inter alia, for the treatment of hyperproliferative disorders.
Novel Heterocyclic Carboxamides As Modulators Of Kinase Activity
- Darmstadt, DE Xiaoling CHEN - Chestnut Hill MA, US Yufang XIAO - Lexington MA, US Ruoxi LAN - Waltham MA, US Lizbeth Celeste DE SELM - Melrose MA, US Constantin NEAGU - Belmont MA, US Justin POTNICK - Acton MA, US Srinivasa R. KARRA - Pembroke MA, US Theresa L. JOHNSON - Salem MA, US
The invention provides novel heterocyclic carboxamide compounds compounds according to Formula (I) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
- Darmstadt, DE Ruoxi LAN - Waltham MA, US Justin POTNICK - Acton MA, US Lizbeth Celeste DESELM - Melrose MA, US Constantin NEAGU - Belmont MA, US Xiaoling CHEN - Chestnut Hill MA, US Roch BOIVIN - North Chelmsford MA, US Theresa L. JOHNSON - Salem MA, US Andreas GOUTOPOULOS - Boston MA, US
International Classification:
C07D 253/08 C07D 403/12 C07D 401/12
Abstract:
Novel azaquinazoline carboxamide derivatives of formula (I)wherein W, W, W, W, R, R, Rand m which are defined above, are p70S6K inhibitor, and can be employed, inter alia, for the treatment of hyperproliferative disorders.
Heteroaryl Compounds As Btk Inhibitors And Uses Thereof
- Darmstadt, DE Jeyaprakashnarayanan SEENISAMY - Karnataka, IN Lesley LIU-BUJALSKI - Bedford MA, US Richard D. CALDWELL - Brookline MA, US Justin POTNICK - Acton MA, US Hui QIU - Acton MA, US Constantin NEAGU - Belmont MA, US Reinaldo JONES - Lowell MA, US Annie Cho WON - Somerville MA, US Andreas GOUTOPOULOS - Boston MA, US Brian A. SHERER - Nashua NH, US Theresa L. JOHNSON - Salem MA, US Anna GARDBERG - Arlington MA, US
International Classification:
C07D 471/04 C07D 519/00
Abstract:
The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
Justin Potnick Wellesley, MA 30 Mark Potnick Pataskala, OH 58 Mark Potnick Columbus, OH 28 Jan Potnick Pataskala, OH 59. People Search. Their First Name ...
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Justin Potnick
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Acton, MA Columbus, OH Chapel Hill, NC Pataskala, OH Boston, MA