Molly I-Chin Busby - Midland MI, US Karen A. Coppens - Midland MI, US Mark J. Hall - Midland MI, US
International Classification:
C11D 17/00
US Classification:
510438
Abstract:
Described are encapsulated time-release cleaning agents, comprising active agents that, when combined with an aqueous phase, have slight delay release, moderate delay release, and/or extended delay release. The invention also relates to the manufacture and use of such compositions.
True L. Rogers - Bomlitz-Benefeld, DE Debora L. Holbrook - Pinconning MI, US Karen A. Coppens - Midland MI, US Robert L. Schmitt - Annandale NJ, US
International Classification:
C09D 101/26 B05D 1/02
US Classification:
1061721, 4274274
Abstract:
The present disclosure Is directed to cellulose ether compositions for film-forming coating applications. A coating composition is provided which contains an aqueous solution of either a very low viscosity cellulose ether or a low-hydroxypropyl cellulose ether, the coating composition having low color, The low viscosity of the cellulose ether component enables the coating composition to contain a high concentration of cellulose ether. Provision of these high concentration cellulose ether coating solutions improves production efficiency by reducing the time required to coat a substrate.
High amounts of active ingredients, such as drugs, can be incorporated into a multilayer melt-extruded film which comprises i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient; and ii) one or more removable protective layers which leave the active ingredient layer(s) substantially intact upon removal of the protective layer(s).
Biologically Active Composition Comprising Ethylcellulose
Mark J. Hall - Midland MI, US Karen A. Coppens - Midland MI, US Pamela S. Larsen - North Brunswick NJ, US Shawn A. Mitchell - Midland MI, US Michael D. Read - Midland MI, US Uma Shrestha - Bay City MI, US
International Classification:
A61K 38/21 A61P 31/12
US Classification:
424 854
Abstract:
A biologically active composition comprising an ethylcellulose, a polyethylene oxide and a biologically active ingredient, wherein the amount of ethylcellulose is at least about (15) percent, based on the total weight of the composition, can be used in melt-extrusion processes to produce pharmaceutical dosage forms.
The present disclosure is directed to cellulose ether compositions for film-forming coating applications. A coating composition is provided which contains an aqueous solution of either a very low viscosity cellulose ether or a low-hydroxypropyl cellulose ether, the coating composition having low color. The low viscosity of the cellulose ether component enables the coating composition to contain a high concentration of cellulose ether. Provision of these high concentration cellulose ether coating solutions improves production efficiency by reducing the time required to coat a substrate.
- Midland MI, US Karen A. Coppens - Midland MI, US Mark J. Hall - Gaylord MI, US Jin Zhao - Midland MI, US
Assignee:
DOW GLOBAL TECHNOLOGIES LLC - Midland MI
International Classification:
A61K 9/48
US Classification:
424451
Abstract:
An injection-molded shell of a dosage form of good quality is producible by a) providing a composition comprising i) from 25 to 90 weight percent of ethylcellulose, ii) from 7.5 to 60 weight percent of a polysaccharide or polysaccharide derivative being different from ethylcellulose, and iii) from 2.5 to 50 weight percent of at least one component being different from polysaccharides and polysaccharide derivatives, based on the total weight of the composition, with the proviso that the composition comprises zero or not more than 10 weight percent of gelatin and zero or not more than 10 weight percent of a polymer comprising homo- or copolymerized acrylic acid, homo- or copolymerized methacrylic acid, a homo- or copolymerized acrylate or a homo- or copolymerized methacrylate, and b) subjecting the composition to shearing and heat to plasticize the composition and injection-molding the plasticized composition into a three-dimensional shell of a dosage form.