A cover for the handle of a shopping cart or similar devices, to reduce the transmission of contaminants present on such handles, comprises a bag having front and rear members, the members being connected such that an opening is formed therebetween; each member having an inner surface and an outer surface, the inner surfaces facing each other; a fastening means attached to each inner surface, the fastening means being positioned so as to interact with each other; a utility pocket attached to the front member; the utility pocket further comprising a storage pouch therein; and a transport pocket which is attached to the rear member, the transport pocket being sized to contain the cover therein when the cover is compacted; and the cover sized to fit onto the handle assembly of a cart, thereby forming a barrier between the handle and a user.