Karl H Clodfelter
age ~47
from Brighton, MA
- Also known as:
-
- Keith Clodfelter
Karl Clodfelter Phones & Addresses
- Brighton, MA
- 8265 Sebring Ct, Severn, MD 21144 • (617)2335039
- Rochester, NY
- 25 Larose Pl, Brighton, MA 02135
Work
-
Company:TessellaFeb 2013
-
Address:Newton, MA
-
Position:Analyst programmer
Education
-
Degree:PhD
-
School / High School:Boston University2000 to 2007
-
Specialities:Bioinformatics
Skills
Bioinformatics • Drug Discovery • Structural Biology • Life Sciences • Drug Design • Genetics • Cheminformatics • Biochemistry • Molecular Modeling • Assay Development • Computational Biology • Medicinal Chemistry • Computational Chemistry • Molecular Dynamics • Pcr • Lifesciences • Java • Docking • Homology Modeling • Perl • C# • Spotfire • Amazon Web Services • Cloud Applications
Languages
English
Interests
Photography • Juggling • Geocaching
Industries
Biotechnology
Resumes
Cloud Operations Manager
view sourceLocation:
Boston, MA
Industry:
Biotechnology
Work:
Tessella - Newton, MA since Feb 2013
Analyst Programmer
FORMA Therapeutics Oct 2008 - Jan 2012
Scientist
SolMap Pharmaceuticals Jun 2007 - Sep 2008
Post-Doctoral Associate
Boston University Sep 2000 - Jan 2007
Graduate Student
Howard Hughes Medical Institute Jun 1998 - Sep 2000
Research Technician
Analyst Programmer
FORMA Therapeutics Oct 2008 - Jan 2012
Scientist
SolMap Pharmaceuticals Jun 2007 - Sep 2008
Post-Doctoral Associate
Boston University Sep 2000 - Jan 2007
Graduate Student
Howard Hughes Medical Institute Jun 1998 - Sep 2000
Research Technician
Education:
Boston University 2000 - 2007
PhD, Bioinformatics University of Rochester 1994 - 1998
BS, Molecular Genetics, minor in Chemistry Old Mill High School 1990 - 1994
PhD, Bioinformatics University of Rochester 1994 - 1998
BS, Molecular Genetics, minor in Chemistry Old Mill High School 1990 - 1994
Skills:
Bioinformatics
Drug Discovery
Structural Biology
Life Sciences
Drug Design
Genetics
Cheminformatics
Biochemistry
Molecular Modeling
Assay Development
Computational Biology
Medicinal Chemistry
Computational Chemistry
Molecular Dynamics
Pcr
Lifesciences
Java
Docking
Homology Modeling
Perl
C#
Spotfire
Amazon Web Services
Cloud Applications
Drug Discovery
Structural Biology
Life Sciences
Drug Design
Genetics
Cheminformatics
Biochemistry
Molecular Modeling
Assay Development
Computational Biology
Medicinal Chemistry
Computational Chemistry
Molecular Dynamics
Pcr
Lifesciences
Java
Docking
Homology Modeling
Perl
C#
Spotfire
Amazon Web Services
Cloud Applications
Interests:
Photography
Juggling
Geocaching
Juggling
Geocaching
Languages:
English
Us Patents
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Novel Compounds And Compositions For The Inhibition Of Nampt
view source -
US Patent:20130273034, Oct 17, 2013
-
Filed:Sep 2, 2011
-
Appl. No.:13/820496
-
Inventors:Kenneth W. Bair - Watertown MA, US
Timm R. Baumeister - Watertown MA, US
Alexandre J. Buckmelter - Watertown MA, US
Karl H. Clodfelter - Watertown MA, US
Bingsong Han - Watertown MA, US
Jian Lin - Watertown MA, US
Dominic J. Reynolds - Watertown MA, US
Chase C. Smith - Watertown MA, US
Zhongguo Wang - Watertown MA, US
Xiaozhang Zheng - Watertown MA, US
Po-Wai Yuen - Beijing, CN -
International Classification:C07D 401/12
C07D 213/40
A61K 31/4406
A61K 45/06
C07D 471/04
A61K 31/437
C07D 213/74
A61K 31/44
A61K 31/4545
A61K 31/5377 -
US Classification:4241331, 546194, 514318, 546331, 514357, 544130, 5142355, 546121, 514300, 546306, 514353, 424649, 514171, 514 34, 424 946, 514 193, 514274
-
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
-
Piperidine Derivatives And Compositions For The Inhibition Of Nicotinamide Phosphoribosyltransferase (Nampt)
view source -
US Patent:20230110003, Apr 13, 2023
-
Filed:Sep 9, 2022
-
Appl. No.:17/941061
-
Inventors:- Boston MA, US
Timm R. Baumeister - Cambridge MA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Brighton MA, US
Bingsong Han - Westwood MA, US
Judith D. Kuntz - Watertown MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Stoneham MA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Lexington MA, US
Xiaozhang Zheng - Lexington MA, US -
International Classification:C07D 519/00
C07D 215/48
C07D 471/04
C07D 513/04
A61K 31/4545
A61K 31/5377
A61K 45/06
A61K 31/437
A61K 31/4709
A61K 31/497
C07D 495/04 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:Formula (I)
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Novel Compounds And Compositions For The Inhibition Of Nampt
view source -
US Patent:20210244717, Aug 12, 2021
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Filed:Sep 11, 2020
-
Appl. No.:17/018196
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Inventors:- Boston MA, US
- South San Francisco CA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Brighton MA, US
Peter Dragovich - South San Francisco CA, US
Francis Gosselin - South San Francisco CA, US
Bingsong Han - Westwood MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Stoneham MA, US
Bruce Roth - South San Francisco CA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Lexington MA, US
Po-Wai Yuen - Beijing, CN
Xiaozhang Zheng - Lexington MA, US -
International Classification:A61K 31/4355
C07D 471/04
C07D 491/04
C07D 495/04
A61K 31/4365
A61K 31/437
A61K 31/496
A61K 31/497
A61K 31/519
A61K 31/5377
A61K 31/55
A61K 45/06
C07D 487/04
C07D 491/048 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
-
Piperidine Derivatives And Compositions For The Inhibition Of Nicotinamide Phosphoribosyltransferase (Nampt)
view source -
US Patent:20210246147, Aug 12, 2021
-
Filed:Sep 16, 2020
-
Appl. No.:17/022906
-
Inventors:- Boston MA, US
Timm R. Baumeister - Cambridge MA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Brighton MA, US
Bingsong Han - Westwood MA, US
Judith D. Kuntz - Watertown MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Stoneham MA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Lexington MA, US
Xiaozhang Zheng - Lexington MA, US -
International Classification:C07D 519/00
C07D 215/48
C07D 471/04
C07D 513/04
A61K 31/4545
A61K 31/5377
A61K 45/06
A61K 31/437
A61K 31/4709
A61K 31/497
C07D 495/04 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)
-
Novel Compounds And Compositions For The Inhibition Of Nampt
view source -
US Patent:20200283403, Sep 10, 2020
-
Filed:Mar 20, 2020
-
Appl. No.:16/824885
-
Inventors:- Watertown MA, US
- South San Francisco CA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Brighton MA, US
Bingsong Han - Westwood MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Stoneham MA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Lexington MA, US
Xiaozhang Zheng - Lexington MA, US
Po-Wai Yuen - Beijing, CN -
International Classification:C07D 401/12
C07C 317/42
C07D 213/54
C07D 213/74
C07D 213/75
C07D 213/81
C07D 213/84
C07D 471/04
A61K 31/437
A61K 31/44
A61K 31/4406
A61K 31/4545
A61K 31/5377
A61K 45/06
C07D 213/40 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An embodiment of the invention is the provision of a compound of Formula IIIA.
-
Novel Compounds And Compositions For The Inhibition Of Nampt
view source -
US Patent:20190388405, Dec 26, 2019
-
Filed:Aug 12, 2019
-
Appl. No.:16/538208
-
Inventors:- Watertown MA, US
- South San Francisco CA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Brighton MA, US
Peter Dragovich - South San Francisco CA, US
Francis Gosselin - South San Francisco CA, US
Bingsong Han - Westwood MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Stoneham MA, US
Bruce Roth - South San Francisco CA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Lexington MA, US
Po-Wai Yuen - Beijing, CN
Xiaozhang Zheng - Lexington MA, US -
International Classification:A61K 31/4355
C07D 491/048
C07D 487/04
A61K 45/06
A61K 31/55
A61K 31/5377
A61K 31/519
A61K 31/497
A61K 31/496
A61K 31/437
A61K 31/4365
C07D 495/04
C07D 491/04
C07D 471/04 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
-
Novel Compounds And Compositions For The Inhibition Of Nampt
view source -
US Patent:20190270721, Sep 5, 2019
-
Filed:May 22, 2019
-
Appl. No.:16/419333
-
Inventors:- Watertown MA, US
- South San Francisco CA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Brighton MA, US
Bingsong Han - Westwood MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Stoneham MA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Lexington MA, US
Xiaozhang Zheng - Lexington MA, US
Po-Wai Yuen - Beijing, CN -
International Classification:C07D 401/12
C07D 213/40
A61K 31/437
A61K 31/44
A61K 31/4406
A61K 31/4545
A61K 31/5377
C07C 317/42
C07D 471/04
C07D 213/84
C07D 213/81
C07D 213/75
C07D 213/74
C07D 213/54
A61K 45/06 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An embodiment of the invention is the provision of a compound of Formula IIIA.
-
Piperidine Derivatives And Compositions For The Inhibition Of Nicotinamide Phosphoribosyltransferase (Nampt)
view source -
US Patent:20190031686, Jan 31, 2019
-
Filed:Jun 7, 2018
-
Appl. No.:16/002651
-
Inventors:- Watertown MA, US
Timm R. Baumeister - Watertown MA, US
Alexandre J. Buckmelter - Acton MA, US
Karl H. Clodfelter - Watertown MA, US
Bingsong Han - Westwood MA, US
Judith D. Kuntz - Watertown MA, US
Jian Lin - Acton MA, US
Dominic J. Reynolds - Watertown MA, US
Chase C. Smith - Rutland MA, US
Zhongguo Wang - Watertown MA, US
Xiaozhang Zheng - Lexington MA, US -
International Classification:C07D 519/00
A61K 45/06
A61K 31/4545
C07D 495/04
A61K 31/4709
A61K 31/497
C07D 215/48
A61K 31/5377
C07D 513/04
C07D 471/04
A61K 31/437 -
Abstract:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
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Karl Clodfelter
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