Karl R Vandermeid

US Patent:

6899885, May 31, 2005

Filed:

Jul 26, 2002

Appl. No.:

10/205972

Inventors:

Dexiang Chen - Madison WI, US
Karl R. VanDerMeid - Rochester NY, US
John C. McMichael - Rochester NY, US
Vicki L. Barniak - Fairport NY, US

Assignee:

Wyeth Holdings Corporation - Madison NJ

International Classification:

A61K039/02
A61K039/00
C07H021/04
C12P021/06
C12N001/20

US Classification:

4242511, 4242001, 4241901, 4241851, 4241841, 536 237, 536 243, 435 691, 435 693, 4352523

Abstract:

A protein from , designated the 74 kD protein, is isolated and purified. The 74 kD protein has an amino-terminal amino acid sequence which is conserved among various strains of. The protein has a molecular weight of approximately 74. 9 kD as measured on a 10% SDS-PAGE gel, while its molecular weight as measured by mass spectrometry is approximately 74 kD. The 74 kD protein is used to prepare a vaccine composition which elicits a protective immune response in a mammalian host, to protect the host against disease caused by.

US Patent:

6461618, Oct 8, 2002

Filed:

Oct 21, 1999

Appl. No.:

09/355398

Inventors:

Dexiang Chen - Madison WI
Karl R. VanDerMeid - Rochester NY
John C. McMichael - Rochester NY
Vicki L. Barniak - Rochester NY

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A61K 3902

US Classification:

4242511, 4242001, 4241901, 4241851, 4241841, 536 231, 536 237, 536 243, 536 2432, 435 691, 435 693, 435 697, 4352523, 4353201, 435325

Abstract:

A protein from the designated the 74 kD protein is isolated and purified. The 74 kD protein has an amino-terminal amino acid sequence which is conserved among various strains of. The protein has a molecular weight of approximately 74,9 kD as measured on a 10% SDS-PAGE gel, while its molecular weight as measured by mass spectrometry is approximately 74 kD. The 74 kD protein is used to prepare a vaccine composition which elicits a protective immune response in a mammalian host to protect the host again disease caused by.