Katherine A Cook

US Patent:

20230039987, Feb 9, 2023

Filed:

Jul 19, 2022

Appl. No.:

17/868656

Inventors:

- Maple Grove MN, US
- Boston MA, US
Samantha Berry - Brighton MA, US
Katherine A. Cook - Allston MA, US
Mark Grinstaff - Brookline MA, US

Assignee:

Boston Scientific Scimed, Inc. - Maple Grove MN
Trustees of Boston University - Boston MA

International Classification:

A61K 31/75
A61K 31/785
A61K 31/795
A61K 31/765
A61K 9/06

Abstract:

Methods of forming a gel and related methods of treating subjects with such gels are described. The method may include preparing a composition by combining a macromer comprising a first polyethylene glycol (PEG)-based polymer, a poly(ethylenimine)-based polymer, or a poly(1,2-glycerol) carbonate-based polymer, the macromer including at least one first functional moiety, a crosslinking agent comprising a second PEG-based polymer that includes at least one second functional moiety, and a photoinitiator, and activating the photoinitiator via a light source to form the gel.

US Patent:

20210361745, Nov 25, 2021

Filed:

May 21, 2021

Appl. No.:

17/327011

Inventors:

- BOSTON MA, US
Amanda WILLIAMSON - Boston MA, US
Jack KIRSCH - Boston MA, US
Katherine COOK - Wheaton IL, US
Ara NAZARIAN - Boston MA, US
Edward K. RODRIGUEZ - Boston MA, US

Assignee:

TRUSTEES OF BOSTON UNIVERSITY - BOSTON MA
BETHISRAEL DEACONESS MEDICAL CENTER - BOSTON MA

International Classification:

A61K 38/22
A61K 9/16
A61P 19/02
A61P 19/04
A61K 9/00

Abstract:

The present invention provides compositions and methods for the treatment of diseases and disorders. In some embodiments the compositions and methods involve administration of a microparticle, or composition thereof that includes an antifibrotic.