Katherine Roberts

Address:

3311 W 8 St, Cincinnati, OH 45205

VIN:

1HD1CX31X7K407460

Make:

Cadillac

Model:

Escalade ESV AWD 4dr

Year:

2007

Address:

1544 Wittekind Ter, Cincinnati, OH 45224

VIN:

JTNBE46K173029148

Make:

TOYOTA

Model:

CAMRY

Year:

2007

US Patent:

20040058855, Mar 25, 2004

Filed:

Mar 18, 2003

Appl. No.:

10/392104

Inventors:

James Schwartz - West Chester OH, US
George Polson - Harwinton CT, US
Patricia Turley - Orange CT, US
John Nelson - Bethlehem CT, US
David Gavin - Cheshire CT, US
Katherine Roberts - Derby CT, US
Carl Margraf - Cincinnati OH, US
David Kaufman - Fairfield OH, US
Randall Marsh - West Chester OH, US

International Classification:

A61K038/16
A61K031/555
A61K031/28

US Classification:

514/006000, 514/184000, 514/495000

Abstract:

Disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric that is capable of delivering a zinc ion across a cellular membrane wherein the minimum inhibitory concentration (MIC) of the zinc ionophoric material is less than about 500 ppm. Further disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric material that is capable of delivering a zinc ion across a cellular membrane wherein the zinc ionophoric material is in combination with a zinc containing material and further wherein there is an increase in an intracellular zinc level by 1.5 fold more than would occur in the absence of the zinc ionophoric material.