Compounds and compositions are disclosed in which a NAMPT Drug Unit is linked to a targeting Ligand Unit through a Unit from which a NAMPT inhibitor compound or derivative thereof is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease, using the compounds and compositions of the invention are also disclosed.
University of Washington- (N.W.R.C.E.) - Seattle, WA since May 2006
Research Scientist II
Meridian Valley Laboratory Sep 2005 - May 2006
Chemist
Cell Therapeutics, Inc. - Seattle, WA Jul 2001 - Aug 2005
Scientist I
Virginia Commonwealth University Jun 2000 - Aug 2000
Research Assistant
Education:
Western Washington University 1996 - 2001
B.S., Chemistry
Skills:
Drug Discovery Organic Synthesis High Throughput Screening Nmr Assay Development Biotechnology Drug Design Molecular Modeling Validation Hplc Purification Proteomics Mass Spectrometry Protein Chemistry Lc Ms Organic Chemistry Genomics Medicinal Chemistry Small Molecules Database Administration