Kelley R Smith

US Patent:

20110107455, May 5, 2011

Filed:

Dec 7, 2007

Appl. No.:

12/517906

Inventors:

Justin M. Lira - Fishers IN, US
Terry R. Wright - Westfield IN, US
Sean M. Russell - Indianapolis IN, US
Donald J. Merlo - Carmel IN, US
Steven Robert Webb - Westfield IN, US
Nicole L. Arnold - Carmel IN, US
Andrew E. Robinson - Indianapolis IN, US
Kelley A. Smith - Lebanon IN, US

Assignee:

Dow AgroSciences LLC - Indianapolis IN

International Classification:

C12N 15/82
C12N 5/10
C12N 15/63
C12Q 1/04
A01H 5/10
A01H 1/00
C12N 9/10
C12N 1/21
A01N 57/18
C12Q 1/68
A01H 5/00

US Classification:

800278, 435418, 4353201, 435 34, 800300, 435468, 435193, 4352523, 504198, 435 6, 8003001

Abstract:

The subject invention relates to a novel gene referred to herein as DSM-2. This gene was identified in A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins, DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.