Robert Allen Snow - West Chester PA Paul Mark Henrichs - Houston TX Daniel Joseph Delecki - Radnor PA William Anthony Sanderson - late of Wayne PA Vinay Chandrakant Desai - Phoenixville PA Edward Bacon - Audubon PA Kenneth Robert Hollister - Chester Springs PA Eric Paul Hohenschuh - Berwyn PA
Assignee:
Nycomed Imaging AS - Oslo
International Classification:
A61K 4900
US Classification:
424 96, 548 3, 548223, 549402, 549427, 549455
Abstract:
This invention provides a physiologically tolerable light imaging contrast agent compound having a molecular weight in the range 500 to 5000000 and containing at least two chromophores having delocalized electron systems as well as at least one polyalkylene oxide (PAO) moiety having a molecular weight in the range 60 to 100000.
Paul Mark Henrichs - Houston TX Marten Eriksen - Oslo, NO Pal Rongved - Oslo, NO Wolfgang Hans Heinrich Gunther - West Chester PA Robert Allen Snow - West Chester PA Kenneth Robert Hollister - Chester Springs PA Gregory Lynn McIntire - West Chester PA Steven Blair Coffey - Pawcatuk CT
The invention relates to a method of generating an image of an animate human or non-human animal body or part thereof. The method comprises administering to said body a physiologically tolerable contrast agent comprising a radiation absorbing component and/or a pressure inducing component, exposing said body to radiation, detecting pressure waves generated in said body by said radiation and generating an optoacoustic image therefrom of at least a part of said body containing the administered contrast agent.
Paramagnetic Material-Containing Magnetic Resonance External Marker Or Calibration Composition
Karen Catherin Briley-Saebo - Oslo, NO Kenneth Kellar - Wayne PA, US David Ladd - Wayne PA, US Kenneth Hollister - Wayne PA, US Atle Bjornerud - Oslo, NO
Assignee:
NYCOMED IMAGING AS.
International Classification:
A61K049/00
US Classification:
424/009360, 424/009364
Abstract:
This invention relates to a set of aqueous marker compositions, each composition having a selected 1/Tvalue which is substantially invariant over an at least 10 C. temperature range between 15 and 40 C. and preferably over an at least 2% magnetic field strength range about a selected field strength value between 0.01 and 5T and comprising an aqueous matrix material having a non-zero 1/Ttemperature dependence within said temperature range with distributed therein a first paramagnetic material having a Trelaxivity which is substantially invariant within said range(s) and/or a second paramagnetic material having within said ranges(s) and Trelaxivity which has a non-zero temperature dependence of opposite polarity to the temperature dependence of 1/Tof said matrix material, said set containing a plurality of said compositions with different selected 1/Tvalues preferably encompassing at least the range 1.0 to 2.5 s, said set preferably comprising at least one said composition containing said second paramagnetic material and at least one said composition containing said first paramagnetic material, where i in Tis 1 or 2.
Element For Photographic Use Containing Crosslinkable Polymers Having Acrylamidophenol Units
Gerald A. Campbell - Webster NY Kenneth R. Hollister - Pittsford NY Richard C. Sutton - Rochester NY
Assignee:
Eastman Kodak Company - Rochester NY
International Classification:
G03C 178 G03C 196 G03C 168
US Classification:
430536
Abstract:
Copolymers containing an acrylamidophenol as a crosslinking site and the corresponding crosslinked polymers are disclosed. The acrylamidophenol unit can be copolymerized with a wide variety of other monomers to provide crosslinkable and crosslinked polymers with useful properties. The acrylamidophenol unit provides for crosslinking at low pH with conventional crosslinking agents. The acrylamidophenol monomer unit is present in the copolymer from about 0. 5 to 50 percent by weight and has the formula: ##STR1## wherein: x is 1 or 0, L is a linking group, R represents hydrogen or methyl, and R. sup. 1 through R. sup. 5 are independently selected from the group consisting of hydrogen, hydroxy, alkyl from 1 to 6 carbon atoms and aryl from 6 to 10 carbon atoms; with the proviso that at least one of R. sup. 1 through R. sup. 5 is hydroxy and at least one of the positions ortho or para to said hydroxy has a hydrogen atom attached thereto.
Crosslinkable Polymers Derived From Amide Compounds
Ignazio S. Ponticello - Rochester NY Kenneth R. Hollister - Pittsford NY Richard C. Tuites - Rochester NY
Assignee:
Eastman Kodak Company - Rochester NY
International Classification:
C08F 2608
US Classification:
526263
Abstract:
Compounds useful in making crosslinkable polymers having the formula (I): ##STR1## wherein R is hydrogen or methyl; R. sup. 1 is cyano or ##STR2## wherein R. sup. 2 is alkyl; Z is --X--R. sup. 3 --X-- or ##STR3## wherein each --X-- is --O-- or --NR. sup. 4 --, provided at least one --X-- is --NR. sup. 4 -- wherein R. sup. 4 is hydrogen or alkyl, R. sup. 3 is divalent hydrocarbon and D. sub. 1 and D. sub. 2 together are the carbon atoms necessary to complete a 5 to 7 membered ring. These compounds can be homopolymerized or copolymerized with each other or with other polymerizable ethylenically unsaturated monomers to give crosslinkable polymers. Such polymers can be purified by conventional purification techniques such as dialysis, diafiltration, ultrafiltration without losing their capability of crosslinking. The resulting purified polymers are particularly useful in photographic materials as gelatin extenders, binders or polymeric color couplers.
Crosslinkable Polymers Containing Acrylamidophenol Units
Gerald A. Campbell - Webster NY Kenneth R. Hollister - Pittsford NY Richard C. Sutton - Rochester NY
Assignee:
Eastman Kodak Company - Rochester NY
International Classification:
C08F 2238 C08F12238 C08F21204 C08F22058
US Classification:
525261
Abstract:
Copolymers containing an acrylamidophenol as a crosslinking site and the corresponding crosslinked polymers are disclosed. The acrylamidophenol unit can be copolymerized with a wide variety of other monomers to provide crosslinkable and crosslinked polymers with useful properties. The acrylamidophenol unit provides for crosslinking at low pH with conventional crosslinking agents. The acrylamidophenol monomer unit is present in the copolymer from about 0. 5 to 50 percent by weight and has the formula: ##STR1## wherein: x is 1 or 0, L is a linking group, R represents hydrogen or methyl, and R. sup. 1 through R. sup. 5 are independently selected from the group consisting of hydrogen, hydroxy, alkyl from 1 to 6 carbon atoms and aryl from 6 to 10 carbon atoms; with the proviso that at least one of R. sup. 1 through R. sup. 5 is hydroxy and at least one of the positions ortho or para to said hydroxy has a hydrogen atom attached thereto.
Thermal And Mechanical Barrier Layers For Optical Recording Elements
Kenneth R. Hollister - Pittsford NY Harold T. Thomas - Rochester NY
Assignee:
Eastman Kodak Company - Rochester NY
International Classification:
G03E 176 G01D 1510 G11B 724
US Classification:
430 14
Abstract:
Improved thermal and mechanical barrier layers coated on the recording layer of an optical recording element are disclosed. The improved layers comprise water-soluble polymers having a glass transition temperature when dry of at least 100. degree. C. and preferably at least 150. degree. C. These barrier layers are easily coated and do not significantly degrade the performance of the element. Optional layers such as spacer layers and topcoat layers coated on the barrier layers are also disclosed.
Ignazio S. Ponticello - Rochester NY Kenneth R. Hollister - Rochester NY Richard C. Tuites - Rochester NY
International Classification:
C07C103133
US Classification:
560178
Abstract:
Compounds useful in making crosslinkable polymers having the formula (I): ##STR1## wherein R is hydrogen or methyl; R. sup. 1 is cyano or ##STR2## wherein R. sup. 2 is alkyl; Z is --X--R. sup. 3 --X-- or ##STR3## wherein each --X-- is --O-- or --NR. sup. 4 --, provided at least one --X-- is --NR. sup. 4 -- wherein R. sup. 4 is hydrogen or alkyl, R. sup. 3 is divalent hydrocarbon and D. sub. 1 and D. sub. 2 together are the carbon atoms necessary to complete a 5 to 7 membered ring. These compounds can be homopolymerized or copolymerized with each other or with other polymerizable ethylenically unsaturated monomers to give crosslinkable polymers. Such polymers can be purified by conventional purification techniques such as dialysis, diafiltration, ultrafiltration without losing their capability of crosslinking. The resulting purified polymers are particularly useful in photographic materials as gelatin extenders, binders or polymeric color couplers.
Ken Hollister (2004-2008), Michael Haak (1975-1979), Christina Lohr (2004-2008), Donna Fellabom (1983-1987), Charles Young (1958-1962), Michael Seamon (1977-1981)