Kenneth Stauffer

US Patent:

6515011, Feb 4, 2003

Filed:

Dec 18, 2001

Appl. No.:

10/023776

Inventors:

Harold G. Selnick - Ambler PA
James C. Barrow - Harleysville PA
Philippe G. Nantermet - Lansdale PA
Peter D. Williams - Harleysville PA
Kenneth J. Stauffer - Souderton PA
Philip E. Sanderson - Philadelphia PA
Kenneth E. Rittle - Green Lane PA
Matthew M. Morrissette - Pottstown PA
Catherine M. Wiscount - Allentown PA
Lekhanh O. Tran - Norristown PA
Terry A. Lyle - Lederach PA
Donnette D. Staas - Harleysville PA

Assignee:

Merck Co., Inc. - Rahway NJ

International Classification:

A61K 3140

US Classification:

514423, 548538, 548528, 548518, 546111, 5462791, 514422, 514343, 514290

Abstract:

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof, e. g. where R is âCH NH , âCH CH NH , or âCH NHC(O)OC(CH ).

US Patent:

7144899, Dec 5, 2006

Filed:

Feb 5, 2002

Appl. No.:

10/467439

Inventors:

Harold G. Selnick - Ambler PA, US
Mary Beth Young - Lansdale PA, US
Philippe G. Nantermet - Lansdale PA, US
James C. Barrow - Harleysville PA, US
Peter D. Williams - Harleysville PA, US
Terry A. Lyle - Lederach PA, US
Donnette D. Staas - Harleysville PA, US
Kenneth J. Stauffer - Souderton PA, US
Philip E. Sanderson - Philadelphia PA, US

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K 31/4439
C07D 401/12

US Classification:

514340, 514361, 5462687, 5462691, 548127, 548131, 548134

Abstract:

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure Formula (I): wherein u is CH or N; Q is 1)—N(R)CH(R)— wherein the nitrogen atom is attached to R, and Rand Rare independently selected from the group consisting of hydrogen, Ccycloalkyl, and Calkyl, or 2) wherein the nitrogen atom is attached to R, and m is 0, 1, or 2.

US Patent:

55609503, Oct 1, 1996

Filed:

May 31, 1995

Appl. No.:

8/455682

Inventors:

Joseph A. Conte - Waterford NJ
Kenneth R. Stauffer - East Brunswick NJ

Assignee:

Campbell Soup Company - Camden NJ

International Classification:

A23D 700

US Classification:

4263306

Abstract:

A method for reducing the free fatty acid content of frying facts and oils that comprises heating the flying fat or oil to a temperature of less than about 120. degree. C. and stirring into the heated fat or oil less than about 10% by weight of cyclodextrin and less than about 10% by weight of a powdered absorbent to form a slurry. Allowing the slurry mixture to react for less than about one and one half hours and then separating the cyclodextrin, absorbent material and free atty acid from the frying fat or oil, thereby reducing the free fatty acid content of the remaining frying fat or oil.