Kenneth James Sylvester

US Patent:

58852700, Mar 23, 1999

Filed:

Feb 5, 1997

Appl. No.:

8/792349

Inventors:

Jose A. Ortiz - Telford PA
Kenneth J. Sylvester - Churchville PA

Assignee:

Smith Kline Beecham Corporation - Philadelphia PA

International Classification:

A61B 1900

US Classification:

604403

Abstract:

A method and apparatus for automatically transferring a predetermined quantity of a sterile liquid to a vial containing a dry medicament for hydrating the medicament and then transferring the hydrated medicament to a container. To hydrate the medicament, a needle is positioned through a vial septum of the vial and an artificial sensor senses when the needle has been positioned through the vial septum and actuates a pump to transfer a predetermined quantity of sterile liquid into the vial. The needle is then removed from the vial septum and the vial is shaken to mix the liquid and medicament. To transfer the hydrated medicament to a container, another needle is positioned through the vial septum. An artificial sensor senses when the needle has been positioned through the vial septum and actuates the pump to transfer the hydrated medicament to the container.

US Patent:

59479515, Sep 7, 1999

Filed:

Sep 21, 1998

Appl. No.:

9/157903

Inventors:

Jose A. Ortiz - Telford PA
Kenneth J. Sylvester - Churchville PA

Assignee:

Smithkline Beecham Corporation - Philadelphia PA

International Classification:

A61B 1900

US Classification:

604403

Abstract:

A method and apparatus for automatically transferring a predetermined quantity of a sterile liquid to a vial containing a dry medicament for hydrating the medicament and then transferring the hydrated medicament to a container. To hydrate the medicament, a needle is positioned through a vial septum of the vial and an artificial sensor senses when the needle has been positioned through the vial septum and actuates a pump to transfer a predetermined quantity of sterile liquid into the vial. The needle is then removed from the vial septum and the vial is shaken to mix the liquid and medicament. To transfer the hydrated medicament to a container, another needle is positioned through the vial septum. An artificial sensor senses when the needle has been positioned through the vial septum and actuates the pump to transfer the hydrated medicament to the container.

US Patent:

58844570, Mar 23, 1999

Filed:

Feb 5, 1997

Appl. No.:

8/792352

Inventors:

Jose A. Ortiz - Telford PA
Kenneth J. Sylvester - Churchville PA

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

B65B 300

US Classification:

53468

Abstract:

A method of automatically producing a plurality of prefilled, sterile delivery devices with a desired quantity of fluid. The sterile delivery devices each include a hollow barrel with a dispensing nozzle at one end and an open opposite end. A piston plunger is positioned within the open end and is slidable in sealing engagement with the barrel to retain a fluid therein. A tip is secured to the dispensing nozzle. A plurality of the sterile delivery devices are automatically fed along a predetermined path. Tips are then removed from the dispensing nozzles of the sterile delivery devices. The hollow barrels of the sterile delivery devices are then filled through the dispensing nozzles with a desired is quantity of fluid. The dispensing nozzles of the sterile delivery devices are then closed and sealed after the filling step to provide sealed sterile delivery devices with sterile fluid contents.