Kent W Neuenschwander from 27 Suydam Rd, East Millstone, NJ 08873, age 71, Phone: (732)9518481

Chemical Compounds
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US Patent:

6977263, Dec 20, 2005
Filed:

Apr 26, 2001
Appl. No.:

09/843126
Inventors:

Peter C. Astles - Sevenoaks, GB
Paul R. Eastwood - Romford, GB
Olivier Houille - Paris, FR
Julian Levell - Summit NJ, US
Heinz Pauls - Bridgewater NJ, US
Mark Czekaj - Doylestown PA, US
Guyan Liang - Woodbridge NJ, US
Yong Gong - Bridgewater NJ, US
James Pribish - Stewartsville NJ, US
Kent Neuenschwander - Bridgewater NJ, US
Assignee:

Aventis Pharmaceuticals Inc. - Bridgewater NJ
International Classification:

A61K031/445
C07D401/06
US Classification:

514318, 514320, 514324, 514326, 514330, 546193, 546196, 546202, 546214, 546226
Abstract:

Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e. g. , asthma and inflammatory diseases, to name only a few.

Substituted Oxoazaheterocyclyl Compounds
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US Patent:

7612075, Nov 3, 2009
Filed:

Jul 25, 2003
Appl. No.:

10/628093
Inventors:

William R. Ewing - Yardley PA, US
Michael R. Becker - Norristown PA, US
Yong Mi Choi-Sledeski - Belle Mead NJ, US
Heinz W. Pauls - Oakville CA, US
Wei He - Audobon PA, US
Stephen M. Condon - Newton MA, US
Roderick S. Davis - West Chester PA, US
Barbara A. Hanney - Pennsburg PA, US
Alfred P. Spada - Carlsbad CA, US
Christopher J. Burns - Malvern PA, US
John Z. Jiang - Collegeville PA, US
Michael R. Myers - Fishers IN, US
Wan F. Lau - Groton CT, US
Aiwen Li - Audubon PA, US
Gregory B. Poli - Perkasie PA, US
Mark A. Bobko - Exton PA, US
Robert L. Morris - Wayne PA, US
Joseph M. Karpinski - Douglassville PA, US
Timothy F. Gallagher - Harleysville PA, US
Kent W. Neuenschwander - Schwenksville PA, US
Robert D. Groneberg - Boulder CO, US
Jean-Francois Sabuco - Paris, FR
Assignee:

Aventis Pharmaceuticals Inc. - Bridgewater NJ
International Classification:

A61K 31/497
C07D 401/06
US Classification:

51425213, 544362
Abstract:

This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.

Malonamide Derivatives With Antithrombotic Activity
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US Patent:

8143242, Mar 27, 2012
Filed:

Jan 7, 2010
Appl. No.:

12/683736
Inventors:

Henning Steinhagen - Frankfurt am Main, DE
Hauke Szillat - Frankfurt am Main, DE
Markus Follmann - Wülfrath, DE
Reinhard Kirsch - Frankfurt am Main, DE
Volkmar Wehner - Frankfurt am Main, DE
Hans Matter - Frankfurt am Main, DE
Martin Lorenz - Frankfurt am Main, DE
Kent W. Neuenschwander - Bridgewater NJ, US
Anthony C. Scotese - Bridgewater NJ, US
Assignee:

Sanofi-Aventis - Paris
International Classification:

A61K 31/553
A61K 31/4965
A61K 31/44
A61K 31/426
A61K 31/381
A61K 31/167
C07D 281/06
C07D 241/04
C07D 213/65
C07D 277/24
C07D 409/02
C07C 237/20
US Classification:

51421101, 51425502, 514350, 514365, 514444, 514616, 540544, 544383, 546298, 548205, 549 60, 564157
Abstract:

The present invention relates to compounds of formula I,.

Chemical Compounds
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US Patent:

20050228018, Oct 13, 2005
Filed:

Feb 14, 2005
Appl. No.:

11/057809
Inventors:

Peter Astles - Sevenoaks, GB
Paul Eastwood - Romford, GB
Olivier Houille - Paris, FR
Julian Levell - Bernardsville NJ, US
Heinz Pauls - Oakville, CA
Mark Czekaj - Doylestown PA, US
Guyan Liang - Woodbridge NJ, US
Yong Gong - Warrington PA, US
James Pribish - Stewartsville NJ, US
Kent Neuenschwander - Schwenksville PA, US
Assignee:

AVENTIS PHARMACEUTICALS INC. - Bridgewater NJ
International Classification:

A61K031/4545
A61K031/453
C07D049/02
C07D041/02
C07D211/80
US Classification:

514317000, 514318000, 514323000, 514320000, 546193000, 546202000, 546226000
Abstract:

Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.

Novel Hmg-Coa Reductase Inhibitors
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US Patent:

48639575, Sep 5, 1989
Filed:

Dec 21, 1987
Appl. No.:

7/135805
Inventors:

Kent W. Neuenschwander - Ambler PA
John R. Regan - Princeton NJ
Benedict J. Kosmider - Audubon PA
Assignee:

Rorer Pharmaceutical Corporation - Fort Washington PA
International Classification:

A61K 31365
C07D30920
US Classification:

514460
Abstract:

Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof. Pharmaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.

Bicyclic Benzo-Oxy Heterocyclic Ethers And Thioethers, Pharmaceutical Compositions And Use
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US Patent:

47771682, Oct 11, 1988
Filed:

Jan 7, 1988
Appl. No.:

7/142084
Inventors:

Donald E. Kuhla - Doylestown PA
Henry F. Campbell - Lansdale PA
William L. Studt - Harleysville PA
Kent W. Neuenschwander - Ambler PA
Assignee:

Rorer Pharmaceutical Corporation - Fort Washington PA
International Classification:

A61K 31425
A61K 31535
C07D40512
C07D41712
US Classification:

514212
Abstract:

A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting parmacological activity, including anti-secretory and anti-ulcerogenic activity, pharaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.

Substituted Cyclohexene Derivatives As Hmg-Coa Reductase Inhibitors
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US Patent:

49391437, Jul 3, 1990
Filed:

Sep 25, 1989
Appl. No.:

7/412356
Inventors:

John R. Regan - Princeton NJ
Joseph G. Bruno - Sellersville PA
Kent W. Neuenschwander - Ambler PA
Assignee:

Rorer Pharmaceutical Corporation - Fort Washington PA
International Classification:

A61K 31345
C07D40502
US Classification:

514326
Abstract:

Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof. Pharmaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.

Substituted Cyclohexene Derivatives As Hmg-Coa Reductase Inhibitors
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US Patent:

50011448, Mar 19, 1991
Filed:

Apr 17, 1990
Appl. No.:

7/510351
Inventors:

John R. Regan - Princeton NJ
Kent W. Neuenschwander - Ambler PA
Assignee:

Rhone-Poulenc Rorer Pharmaceuticals Inc. - Fort Washington PA
International Classification:

A61K 31385
C07D33908
US Classification:

514436
Abstract:

Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof. Phamaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.