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Kirsten A Rinderspacher

age ~47

from Mount Vernon, NY

Also known as:
  • Alison K Rinderspacher
  • Alison R

Kirsten Rinderspacher Phones & Addresses

  • Mount Vernon, NY
  • Norwich, VT
  • Bronx, NY
  • Danbury, CT
  • Wilder, VT
  • New York, NY
  • Hanover, NH
  • 1575 Thieriot Ave APT 1H, Bronx, NY 10460

Us Patents

  • Potent Non-Urea Inhibitors Of Soluble Epoxide Hydrolase

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  • US Patent:
    20120029022, Feb 2, 2012
  • Filed:
    Jul 7, 2011
  • Appl. No.:
    13/178117
  • Inventors:
    Donald W. Landry - New York NY, US
    Yuli Xie - New York NY, US
    Yidong Liu - New York NY, US
    Gangli Gong - Elmhurst NY, US
    Kirsten Alison Rinderspacher - Bronx NY, US
  • Assignee:
    The Trustees Of Columbia Univesity In The City Of New York - New York NY
  • International Classification:
    A61K 31/445
    A61P 9/12
    A61P 29/00
    C07D 211/62
    A61P 9/00
  • US Classification:
    514330, 546225
  • Abstract:
    The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
  • Triazolopyrimidines, Their Preparation And Use

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  • US Patent:
    20210047337, Feb 18, 2021
  • Filed:
    Oct 30, 2020
  • Appl. No.:
    17/085791
  • Inventors:
    Konstantin Petrukhin - New Windsor NY, US
    Kirsten Alison Rinderspacher - Mount Vernon NY, US
    Andras Varadi - New York NY, US
    Boglarka Racz - New York NY, US
    Peter Bernstein - Philadelphia PA, US
    Patricia C. Weber - Yardley PA, US
    Donald W. Landry - New York NY, US
    Andrew S. Wasmuth - Brooklyn NY, US
  • Assignee:
    The Trustees of Columbia University in the City of New York - New York NY
  • International Classification:
    C07D 487/04
    C07D 519/00
    A61P 27/02
  • Abstract:
    The present invention provides a compound having the structure:wherein R, R, R, R, and Rare each independently H, halogen, CF, C-Calkyl, aryl or heteroaryl; X is N or CR, wherein Ris H, OH, or halogen; A is absent or present, and when present isB has the structure:or a pharmaceutically acceptable salt thereof.
  • Potent Non-Urea Inhibitors Of Soluble Epoxide Hydrolase

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  • US Patent:
    20180305314, Oct 25, 2018
  • Filed:
    Jun 26, 2018
  • Appl. No.:
    16/018770
  • Inventors:
    - New York NY, US
    Yuli Xie - New York NY, US
    Yidong Liu - New York NY, US
    Gangli Gong - Little Neck NY, US
    Kirsten Alison Rinderspacher - Bronx NY, US
  • Assignee:
    THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
  • International Classification:
    C07D 211/96
    C07F 9/59
    C07D 211/62
    C12N 9/99
    C07D 401/12
    C07D 409/12
  • Abstract:
    The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
  • Potent Non-Urea Inhibitors Of Soluble Epoxide Hydrolase

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  • US Patent:
    20160052883, Feb 25, 2016
  • Filed:
    Nov 2, 2015
  • Appl. No.:
    14/930409
  • Inventors:
    - New York NY, US
    Yuli Xie - New York NY, US
    Yidong Liu - New York NY, US
    Gangli Gong - Little Neck NY, US
    Kirsten Alison Rinderspacher - Bronx NY, US
  • Assignee:
    THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
  • International Classification:
    C07D 211/96
  • Abstract:
    The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
  • Potent Non-Urea Inhibitors Of Soluble Epoxide Hydrolase

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  • US Patent:
    20140349368, Nov 27, 2014
  • Filed:
    Feb 17, 2014
  • Appl. No.:
    14/182175
  • Inventors:
    - New York NY, US
    Yuli Xie - New York NY, US
    Yidong Lu - New York NY, US
    Gangli Gong - Elmhurst NY, US
    Kirsten Alison Rinderspacher - Bronx NY, US
  • Assignee:
    THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
  • International Classification:
    C12N 9/99
    C07F 9/59
    C07D 409/12
    C07D 211/62
    C07D 211/96
    C07D 401/12
  • US Classification:
    435184, 546225, 546194, 546213, 546226, 546208, 546 21, 544130
  • Abstract:
    The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
  • Potent Non-Urea Inhibitors Of Soluble Epoxide Hydrolase

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  • US Patent:
    20140336193, Nov 13, 2014
  • Filed:
    Jul 23, 2014
  • Appl. No.:
    14/339183
  • Inventors:
    - New York NY, US
    Stevan Pecic - Astoria NY, US
    Kirsten Alison Rinderspacher - New York NY, US
  • International Classification:
    C07D 211/96
    C07D 405/12
    C07D 401/12
  • US Classification:
    5142372, 546245, 435184, 435375, 514330, 546189, 514316, 546171, 514314, 5462837, 514321, 544130, 546143, 514310
  • Abstract:
    The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
  • Compounds That Inhibit Nfkb And Bace1 Activity

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  • US Patent:
    20140275165, Sep 18, 2014
  • Filed:
    Mar 24, 2014
  • Appl. No.:
    14/223967
  • Inventors:
    - New York NY, US
    Tae-Wan Kim - East Brunswick NJ, US
    Gangli Gong - Little Neck NY, US
    Jeremy C. Hwang - Great Neck NY, US
    Yuli Xie - New York NY, US
    Yidong Liu - New York NY, US
    Kirsten Alison Rinderspacher - Bronx NY, US
  • Assignee:
    The Trustees of Columbia University in the City of New York - New York NY
  • International Classification:
    C07D 215/40
    C07D 401/12
    C07D 409/12
  • US Classification:
    514314, 546171, 514311, 435184
  • Abstract:
    The present invention relates to compounds with activity as BACE1 and NFκB modulators, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease. The present invention is also directed to the treatment of diseases related to dysfunction of cell proliferation, the immune system and/or inflammation using such compounds or pharmaceutical compositions containing such candidate compounds.

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