Methods and imaging agents for imaging epithelial cancer cells in the lymphatic system are disclosed herein. In an embodiment, an imaging agent for imaging cancer cells in a lymphatic system comprises a fluorescent dye conjugated to one or more antibodies. The antibodies are capable of specific binding to an epithelial cell adhesion molecule (Ep-CAM). In addition, embodiments of the imaging agent may be administered to the lymphatic system where the disclosed imaging agents may bind to an epithelial cell adhesion molecule. The bound imaging agents may be excited with excitation light to image cancer cells in the lymphatic system.
Method Of Measuring Propulsion In Lymphatic Structures
Kristen Adams - Houston TX, US Ruchi Sharma - Houston TX, US John Rasmussen - Spring TX, US
Assignee:
BAYLOR COLLEGE OF MEDICINE - Houston TX
International Classification:
A61B 6/00
US Classification:
600431000
Abstract:
Novel methods and imaging agents for functional imaging of lymph structures are disclosed herein. Embodiments of the methods utilize highly sensitive optical imaging and fluorescent spectroscopy techniques to track or monitor packets of organic dye flowing in one or more lymphatic structures. The packets of organic dye may be tracked to provide quantitative information regarding lymph propulsion and function. In particular, lymph flow velocity and pulse frequency may be determined using the disclosed methods.
Method Of Measuring Propulsion In Lymphatic Structures
Kristen ADAMS - Houston TX, US Ruchi SHARMA - Houston TX, US John RASMUSSEN - Spring TX, US
International Classification:
A61K 49/00
US Classification:
424 96, 424 91
Abstract:
Novel methods and imaging agents for functional imaging of lymph structures are disclosed herein. Embodiments of the methods utilize highly sensitive optical imaging and fluorescent spectroscopy techniques to track or monitor packets of organic dye flowing in one or more lymphatic structures. The packets of organic dye may be tracked to provide quantitative information regarding lymph propulsion and function. In particular, lymph flow velocity and pulse frequency may be determined using the disclosed methods.
Physics Teacher, Assistant Soccer and Volleyball Coach at Elkins High School, Adjunct Professor of Biology at Lone Star College Cy Fair
Location:
United States
Work:
Elkins High School - Missouri City, TX since Aug 2013
Physics Teacher, Assistant Soccer and Volleyball Coach
Lone Star College Cy Fair since Apr 2011
Adjunct Professor of Biology
Brazoswood High School - Clute, TX Aug 2011 - Aug 2013
Chemistry Teacher
The University of Texas Health Science Center at Houston Sep 2008 - Dec 2010
Assistant Professor
Baylor College of Medicine May 2006 - Sep 2008
Postdoctoral Fellow
Education:
Rice University 2000 - 2006
Ph.D., Bioengineering
Cornell University 1996 - 2000
B.S., Chemical Engineering
General Electric - Satellite Controller RCA - Member Engineering Staff Exelon - Consultant II GlaxoSmithKline - Consultant Merck & Co. - Consultant Colgate-Palmolive - Consultant Rohm and Haas - Consultant
Education:
Richard Stockton College of New Jersey - BA Criminal Justice, Frostburg State University - MSM Financial Management and Communications, Wharton School of the University of Pennsylvania - Accounting
Kristen Adams
Work:
Kristen Adams Photography - Photographer
Education:
Whatcom Community College, Juanita High School
Bragging Rights:
I have a wonderful Shiba Inu named Mango
Kristen Adams
Work:
Children's Healthcare of Atlanta - Music Therapist (2007) Jones Lang LaSalle - Senior Accounting Manager (2008)
Education:
Florida State University - Music Therapy
Kristen Adams
Work:
Cerner - Operations Support Staff (2011)
Education:
University of Missouri–Kansas City - Business Administration - Marketing
Kristen Adams
Education:
Jsr, Spotsylvania high school
Kristen Adams
Education:
Emerson College - Acting
Kristen Adams
Education:
Shippensburg University of Pennsylvania - Psychology
Kristen Adams
Education:
La Costa Canyon HS, Diegueno Middle School, Park Dale Lane Elementry