Kristin S Lowery

age ~57

from Irvine, CA

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Also known as:

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Kristin Lowery Phones & Addresses

Research

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Position:

Director of Commercial Laboratory Operations at AthoGen/Abbott

Location:

Orange County, California Area

Industry:

Research

Work:

AthoGen/Abbott
Director of Commercial Laboratory Operations

Compositions And Methods For The Treatment Of Severe Acute Respiratory Syndrome (Sars)
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US Patent:

7339051, Mar 4, 2008
Filed:

Apr 26, 2004
Appl. No.:

10/831901
Inventors:

Stanley T. Crooke - Carlsbad CA, US
David J. Ecker - Encinitas CA, US
Rangarajan Sampath - San Diego CA, US
Susan M. Freier - San Diego CA, US
Christian Massire - Carlsbad CA, US
Steven A. Hofstadler - Vista CA, US
Kristin Sannes Lowery - Vista CA, US
Eric E. Swayze - Carlsbad CA, US
Brenda F. Baker - Carlsbad CA, US
C. Frank Bennett - Carlsbad CA, US
Assignee:

Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:

C07H 21/02
C07H 21/04
US Classification:

536 245, 536 231, 536 243, 536 2433
Abstract:

The present invention provides design and synthesis of oligomeric compounds and compositions that can be administered to reduce the activity of SARS virus in vivo or in vitro, to prevent or treat SARS virus-associated disease, to detect AARS virus, and to diagnose SARS virus-associated diseases.

Methods For Rapid Identification And Quantitation Of Nucleic Acid Variants
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US Patent:

8026084, Sep 27, 2011
Filed:

Jul 21, 2006
Appl. No.:

11/491376
Inventors:

David J. Ecker - Encinitas CA, US
Steven A. Hofstadler - Vista CA, US
Thomas A. Hall - Oceanside CA, US
Kristin Sannes Lowery - Vista CA, US
Assignee:

Ibis Biosciences, Inc. - Carlsbad CA
International Classification:

C12P 19/34
US Classification:

435 912
Abstract:

There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products.

Optimization Of Ligand Affinity For Rna Targets Using Mass Spectrometry
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US Patent:

8188011, May 29, 2012
Filed:

May 16, 2000
Appl. No.:

09/573479
Inventors:

Richard Griffey - Vista CA, US
Steven Hofstadler - Oceanside CA, US
Jared J. Drader - Encinitas CA, US
Kristin S. Lowery - Vista CA, US
Assignee:

Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:

C40B 30/00
US Classification:

506 9, 436173, 435 6
Abstract:

The present invention provides methods for the identification ligand compounds that bind to target molecules such as proteins or structured RNA with as little as millimolar (mM) affinity using mass spectrometry. The methods may be used to determine the mode of binding interaction between two or more of these ligand compounds to the target as well as their relative affinities. Also provided are methods for designing compounds having greater affinity to a target molecule by identifying two or more ligands using mass spectrometry methods of the invention and linking the ligands together to form a novel compound.

Molecular Interaction Sites Of 16S Ribosomal Rna And Methods Of Modulating The Same
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US Patent:

20050250133, Nov 10, 2005
Filed:

Mar 1, 2005
Appl. No.:

11/070519
Inventors:

David Ecker - Encinitas CA, US
Steven Hofstadler - Vista CA, US
Richard Griffey - Vista CA, US
Rangarajan Sampath - San Diego CA, US
Kristin Lowery - Vista CA, US
Christian Massire - Carlsbad CA, US
International Classification:

C12Q001/68
G06F019/00
G01N033/48
G01N033/50
US Classification:

435006000, 702020000
Abstract:

Polynucleotides comprising molecular interaction sites of 16S rRNA that have particular secondary structure are provided. Methods of using such polynucleotides to screen, virtually or actually, combinatorial libraries of compounds that bind thereto are also provided. Method of modulating the activity of 16S rRNA by contacting 16S rRNA or prokaryotic cells containing the same with a compound identified by such virtual or actual screening are also provided.

Optimization Of Ligand Affinity For Rna Targets Using Mass Spectrometry
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US Patent:

6770486, Aug 3, 2004
Filed:

Feb 8, 2000
Appl. No.:

09/499875
Inventors:

Richard Griffey - Vista CA
Steven Hofstadler - Oceanside CA
Jared J. Drader - Encinitas CA
Kristin S. Lowery - Vista CA
Venkatraman Mohan - Carlsbad CA
Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA
International Classification:

G01N 2400
US Classification:

436173, 435 6, 435 71, 435 912
Abstract:

The present invention provides methods for the identification ligand compounds that bind to target molecules such as proteins or structured RNA with as little as millimolar (mM) affinity using mass spectrometry. The methods may be used to determine the mode of binding interaction between two or more of these ligand compounds to the target as well as their relative affinities. Also provided are methods for designing compounds having greater affinity to a target molecule by identifying two or more ligands using mass spectrometry methods of the invention and linking the ligands together to form a novel compound.