Kwok S. Yu - San Mateo CA, US Ziyang Zhong - Union City CA, US
International Classification:
A61K 31/395 A61K 31/355
US Classification:
514183, 514458
Abstract:
A pharmaceutical formulation comprising (a) 17-allylamino-17-demethoxy-geldanamycin; (b) an ester of d-α-tocopheryl succinate and polyethylene glycol; and (c) a pharmaceutically acceptable, water-miscible organic solvent.
Spencer H. Lin - Coral Springs FL Kwok Sum Yu - Winter Springs FL Pratap Singh - Miami FL Steven E. Diamond - Coral Springs FL
Assignee:
Dade Behring Inc. - Deerfield IL
International Classification:
G01N 33552 G01N 3378
US Classification:
436527
Abstract:
Methods and compositions are provided for specific binding assays in which specific binding reagents are immobilized on a solid phase. Immobilization is facilitated by covalently coupling specific binding assay reagents such as polypeptide receptors or analytes with water soluble polymers. Such water soluble polymers, for example star polymers such as dendrimers, provide production advantages of lot-to-lot uniformity and homogeneity, and can enhance sensitivity due to low non-specific binding to the solid phase.