Kwok Sum Yu

US Patent:

20070167422, Jul 19, 2007

Filed:

Dec 11, 2006

Appl. No.:

11/637566

Inventors:

Kwok S. Yu - San Mateo CA, US
Ziyang Zhong - Union City CA, US

International Classification:

A61K 31/395
A61K 31/355

US Classification:

514183, 514458

Abstract:

A pharmaceutical formulation comprising (a) 17-allylamino-17-demethoxy-geldanamycin; (b) an ester of d-α-tocopheryl succinate and polyethylene glycol; and (c) a pharmaceutically acceptable, water-miscible organic solvent.

US Patent:

58613196, Jan 19, 1999

Filed:

Oct 28, 1994

Appl. No.:

8/331243

Inventors:

Spencer H. Lin - Coral Springs FL
Kwok Sum Yu - Winter Springs FL
Pratap Singh - Miami FL
Steven E. Diamond - Coral Springs FL

Assignee:

Dade Behring Inc. - Deerfield IL

International Classification:

G01N 33552
G01N 3378

US Classification:

436527

Abstract:

Methods and compositions are provided for specific binding assays in which specific binding reagents are immobilized on a solid phase. Immobilization is facilitated by covalently coupling specific binding assay reagents such as polypeptide receptors or analytes with water soluble polymers. Such water soluble polymers, for example star polymers such as dendrimers, provide production advantages of lot-to-lot uniformity and homogeneity, and can enhance sensitivity due to low non-specific binding to the solid phase.