Susan Eagle - Nashville TN, US Kyle Hocking - Alpharetta GA, US Franz Baudenbacher - Franklin TN, US Colleen Brophy - Nashville TN, US
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61M 5/172 A61B 5/0215
US Classification:
600490, 604 66, 604503
Abstract:
One aspect of the present disclosure is a system for hemodynamic resuscitation. The system includes an intravenous access device having a pressure sensor element configured to detect a peripheral venous pressure value in response to an occlusion of a peripheral vein. The system also includes a controller device that is configured to receive a signal from the pressure sensor comprising the peripheral venous pressure value, to process the signal to determine a hemodynamic parameter based on the peripheral venous pressure value, and to generate a resuscitation score based on the hemodynamic parameter.
Methods And Compositions For Vein Harvest And Autografting
Colleen M. Brophy - Nashville TN, US Padmini Komalavilas - Nashville TN, US Joyce Cheung-Flynn - Nashville TN, US Kyle M. Hocking - Nashville TN, US Susan S. Eagle - Nashville TN, US
International Classification:
A61B 17/00 A01N 1/02
US Classification:
600 36, 435 11
Abstract:
The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided.
Hypovolemia/Hypervolemia And Intravenous Infiltration Detection Using Peripheral Intravenous Waveform Analysis (Piva) And Applications Of Same
- Nashville TN, US Colleen Brophy - Nashville TN, US Kyle Mitchell Hocking - Nashville TN, US Franz Baudenbacher - Franklin TN, US Richard Boyer - Nashville TN, US
International Classification:
A61B 5/0215 A61B 5/00 A61M 5/158 A61M 5/168
Abstract:
Peripheral intravenous (IV) waveform analysis (PIVA) systems and methods for determining an intravascular volume status of a living subject and monitoring an IV line functionality of a peripheral IV device are provided. The PIVA system includes a peripheral IV device and a processing device. The peripheral IV device includes a peripheral IV catheter inserted into a vein of the living subject, and a fluid controlling device to control fluid flow from a fluid source to the peripheral IV catheter. The processing device receives peripheral venous signals from the peripheral IV device, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum; and performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an intravascular volume status of the living subject and/or an IV line functionality of the peripheral IV catheter in real time.
System And Method For Monitoring And Determining Patient Parameters From Sensed Venous Waveform
- Deerfield IL, US - Glattpark (Opfikon), CH Kyle Hocking - Nashville TN, US Susan Eagle - Nashville TN, US Colleen Brophy - Nashville TN, US Richard Boyer - Somerville MA, US Franz Baudenbacher - Nashville TN, US
International Classification:
A61B 5/0215 A61B 5/00 A61B 5/029
Abstract:
Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.
System And Method For Monitoring And Determining Patient Parameters From Sensed Venous Waveform
- Deerfield IL, US - Glattpark (Opfikon), CH Kyle Hocking - Nashville TN, US Susan Eagle - Nashville TN, US Colleen Brophy - Nashville TN, US Richard Boyer - Somerville MA, US Franz Baudenbacher - Nashville TN, US
Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.
Non-Invasive Venous Waveform Analysis For Evaluating A Subject
- Nashville TN, US Kyle M. HOCKING - Nashville TN, US Susan S. EAGLE - Nashville TN, US Franz J. BAUDENBACHER - Nashville TN, US Bret D. ALVIS - Nashville TN, US
International Classification:
A61B 5/0205 A61B 5/029 A61B 8/04 A61B 5/00
Abstract:
An example method includes detecting, via a sensor, vibrations originating from a vein of a subject and obtaining an intensity spectrum of the detected vibrations over a range of frequencies. The method further includes using the obtained intensity spectrum to determine a metric selected from a group that includes: a pulmonary capillary wedge pressure (PCWP), a mean pulmonary arterial pressure, a pulmonary artery diastolic pressure, a left ventricular end diastolic pressure, a left ventricular end diastolic volume, a cardiac output, total blood volume, and a volume responsiveness of the subject. An example computing device and an example non-transitory computer readable medium that are related to the method are disclosed as well.
Intravenous Access Device Having Integrated Hemodynamic Resuscitation System And Related Methods
- Nashville TN, US - Washington DC, US Kyle Hocking - Alpharetta GA, US Franz Baudenbacher - Franklin TN, US Colleen Brophy - Nashville TN, US Richard Boyer - Nashville TN, US
International Classification:
A61M 5/172 A61B 5/0215
Abstract:
One aspect of the present disclosure is a system for hemodynamic resuscitation. The system includes an intravenous access device having a pressure sensor element configured to detect a peripheral venous pressure value in response to an occlusion of a peripheral vein. The system also includes a controller device that is configured to receive a signal from the pressure sensor comprising the peripheral venous pressure value, to process the signal to determine a hemodynamic parameter based on the peripheral venous pressure value, and to generate a resuscitation score based on the hemodynamic parameter.
System And Method For Monitoring And Determining Patient Parameters From Sensed Venous Waveform
- Deerfield IL, US - Glattpark (Opfikon), CH Kyle Hocking - Nashville TN, US Susan Eagle - Nashville TN, US Colleen Brophy - Nashville TN, US Richard Boyer - Somerville MA, US Franz Baudenbacher - Nashville TN, US
International Classification:
A61B 5/0215 A61B 5/00 A61B 5/029
Abstract:
Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.
Vanderbilt University Medical Center
Research Assistant Professor
Volumetrix
President and Chief Executive Officer
Vanderbilt University
Research Assistant Professor
Education:
Vanderbilt University 2010 - 2012
Doctorates, Doctor of Philosophy, Biomedical Engineering, Bioengineering, Philosophy
Vanderbilt University 2005 - 2009
Bachelor of Engineering, Bachelors, Biomedical Engineering