Larry D Allen

US Patent:

6482436, Nov 19, 2002

Filed:

Jan 6, 1999

Appl. No.:

09/226818

Inventors:

Viktor A. Volkonsky - Mosow, RU
Sergei D. Dyuksherstnov - Mosow, RU
Sergi V. Chernyakov - Mosow, RU
Larry M. Allen - Golden CO
Thomas B. Kent - Boulder CO

Assignee:

FeRx Incorporated - San Diego CA

International Classification:

A61K 914

US Classification:

424489, 424490, 424443, 424448, 424445, 424447

Abstract:

A magnetically controllable, or guided, ferrocarbon particle composition and methods of use and production are disclosed. The composition may optionally carry biologically active substances that have been adsorbed onto the particle. The composition comprises composite, volume-compounded particles of 0. 1 to 5. 0 m in size, and preferably between 0. 5 and 5. 0 m, containing 1. 0 to 95. 0% by mass of carbon, and preferably from about 20% to about 60%. The particles may be produced by mechanical milling of a mixture of iron and carbon powders. The obtained particles are optionally placed in a solution of a biologically active substance to adsorb the substance onto the particles. The composition is generally administered in suspension.

US Patent:

20030108614, Jun 12, 2003

Filed:

Jun 24, 2002

Appl. No.:

10/183802

Inventors:

Viktor Volkonsky - Moscow, RU
Sergei Dvukhsherstnov - Moscow, RU
Sergei Chernyakov - Moscow, RU
Larry Allen - Golden CO, US
Thomas Kent - Boulder CO, US

Assignee:

FeRx Incorporated, a Colorado corporation

International Classification:

A61K031/704
A61K031/4745
H01F001/14
A61K009/16
A61K009/50

US Classification:

424/490000, 514/034000, 514/283000, 252/062550

Abstract:

A magnetically controllable, or guided, ferrocarbon particle composition and methods of use and production are disclosed. The composition may optionally carry biologically active substances that have been adsorbed onto the particle. The composition comprises composite, volume-compounded particles of 0.1 to 5.0 m in size, and preferably between 0.5 and 5.0 m, containing 1.0 to 95.0% by mass of carbon, and preferably from about 20% to about 60%. The particles may be produced by mechanical milling of a mixture of iron and carbon powders. The obtained particles are optionally placed in a solution of a biologically active substance to adsorb the substance onto the particles. The composition is generally administered in suspension.

US Patent:

57574740, May 26, 1998

Filed:

Jun 28, 1995

Appl. No.:

8/496061

Inventors:

Bhushan L. Sopori - Denver CO
Larry C. Allen - Arvada CO
Craig Marshall - Littleton CO
Robert C. Murphy - Golden CO
Todd Marshall - Littleton CO

Assignee:

Midwest Research Institute - Kansas City MO

International Classification:

G01N 2188

US Classification:

356 72

Abstract:

A method and apparatus for measuring characteristics of a piece of material, typically semiconductor materials including photovoltaic devices. The characteristics may include dislocation defect density, grain boundaries, reflectance, external LBIC, internal LBIC, and minority carrier diffusion length. The apparatus includes a light source, an integrating sphere, and a detector communicating with a computer. The measurement or calculation of the characteristics is calibrated to provide accurate, absolute values. The calibration is performed by substituting a standard sample for the piece of material, the sample having a known quantity of one or more of the relevant characteristics. The quantity measured by the system of the relevant characteristic is compared to the known quantity and a calibration constant is created thereby.

US Patent:

52760600, Jan 4, 1994

Filed:

Apr 15, 1991

Appl. No.:

7/685609

Inventors:

Edward S. Neiss - Denver CO
Larry M. Allen - Golden CO
Russell T. Jordan - Fort Collins CO

Assignee:

Block/Chemex, G.P. - Jersey City NJ

International Classification:

A61K 3105

US Classification:

514731

Abstract:

The invention relates to methods useful in the treatment of benign, premalignant and malignant solid tumors, especially those of the skin comprising methods for the administration of pharmacologically active compositions containing catecholic butanes. The invention also relates to methods of preventing the occurrence of tumors, and the use of catecholic butanes as a sunscreening agent. The preferred catecholic butane is nordihydroguaiaretic acid. The preferred methods of application of the compositions containing catecholic butanes are by topical application and intratumor injection.

US Patent:

62005472, Mar 13, 2001

Filed:

Jan 6, 1998

Appl. No.:

9/003286

Inventors:

Viktor A. Volkonsky - Moscow, RU
Sergei D. Dyuksherstnov - Moscow, RU
Sergi V. Chernyakov - Moscow, RU
Larry M. Allen - Golden CO
Thomas B. Kent - Boulder CO

Assignee:

FeRx Incorporated - San Diego CA

International Classification:

A61K 916
A61K 950
A61B 5055

US Classification:

424 936

Abstract:

A magnetically controllable, or guided, carrier composition and methods of use and production are disclosed, the composition for carrying biologically active substances to a treatment zone in a body under control of a magnetic field. The composition comprises composite, volume-compounded paclitaxel-adsorbed particles of 0. 2 to 5. 0. mu. m in size, and preferably between 0. 5 and 5. 0. mu. m, containing 1. 0 to 95. 0% by mass of carbon, and preferably from about 20% to about 60%. The particles are produced by mechanical milling of a mixture of iron and carbon powders. The obtained particles are placed in a solution of a biologically active substance to adsorb the substance onto the particles. The composition is generally administered in suspension. Magnetic carrier particles having therapeutic quantities of adsorbed paclitaxel, doxorubicin, Tc. sup.

US Patent:

50082949, Apr 16, 1991

Filed:

Jun 3, 1987

Appl. No.:

7/057481

Inventors:

Edward S. Neiss - Denver CO
Larry M. Allen - Golden CO

Assignee:

Chemex Pharmaceuticals, Inc. - Denver CO

International Classification:

A61K 3105

US Classification:

514731

Abstract:

The invention relates to methods useful in the treatment of benign, premalignant and malignant solid tumors, especially those of the skin comprising methods for the administration of pharmacologically active compositions containing catecholic butanes. The invention also relates to methods of preventing the occurence of tumors, and the use of catecholic butanes as a sunscreening agent. The preferred catecholic butane is nordihydroguaiaretic acid. The preferred methods of application of the compositions containing catecholic butanes are by topical application and intratumor injection.