Laura K Potter

US Patent:

20120115734, May 10, 2012

Filed:

Nov 4, 2010

Appl. No.:

12/939586

Inventors:

Laura Potter - Cary NC, US
Michael Nuccio - Durham NC, US
Rex Dwyer - Raleigh NC, US

International Classification:

C40B 10/00
C40B 60/00

US Classification:

506 1, 506 33

Abstract:

Various systems and methods for selecting candidate biological components and/or combinations of biological components that affect a biological process are described. For example, a computing device may use a computer model to simulate the biological process and predict a phenotypic outcome. In this manner, the impact of candidate components and combinations may be determined using the computer model. The computing device may determine optimal characteristics such as expression levels of biological components that result in a desirable phenotypic outcome of the biological process as predicted by the computer model. The computing device may perform sensitivity analysis around the optimal characteristics. The sensitivity analysis may be used to determine whether the candidate combinations are robust across a range of the optimal characteristics. The computing device may select various candidate components and combinations based on the sensitivity analysis and the predicted phenotypic outcome.

US Patent:

20140317783, Oct 23, 2014

Filed:

Nov 2, 2012

Appl. No.:

14/355251

Inventors:

- Basel, CH
Laura Potter - Research Triangle Park NC, US
Jonathan Cohn - Research Triangle Park NC, US

Assignee:

SYNGENTA PARTICIPATIONS AG - Basel

International Classification:

C12N 15/82

US Classification:

800290, 4353201, 800298

Abstract:

The present invention relates generally to the field of molecular biology and regards various polynucleotides, polypeptides and methods that may be employed to enhance yield in transgenic plants. Specifically the transgenic plants may exhibit increased yield, increased biomass or increased photoassimilation.