Laura Cooper Schouten

US Patent:

7834249, Nov 16, 2010

Filed:

Nov 21, 2007

Appl. No.:

11/943801

Inventors:

Laura C. Schouten - Pittsboro NC, US
Cheryl L. Peters - Raleigh NC, US
Brian Vande Berg - Durham NC, US

Assignee:

Athenix Corporation - Research Triangle Park NC

International Classification:

C12N 15/52
C12N 15/82
C12N 1/21

US Classification:

800300, 435 691, 4352523, 4353201, 435419, 536 232, 800288, 8003001

Abstract:

Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, or 35, or the nucleotide sequence set forth in SEQ ID NO:6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, or 34.

US Patent:

7910805, Mar 22, 2011

Filed:

Jun 8, 2007

Appl. No.:

11/760602

Inventors:

Nicholas B. Duck - Apex NC, US
Todd K. Hinson - Rougemont NC, US
Vadim Beilinson - Cary NC, US
Laura Cooper Schouten - Pittsboro NC, US
Daniel John Tomso - Bahama NC, US

Assignee:

Athenix Corp. - Morrisville NC

International Classification:

C12N 15/52
C12N 15/82

US Classification:

800300, 4352523, 4353201, 435419, 536 232, 800288, 800298, 800302

Abstract:

Compositions and methods for conferring herbicide resistance to and improving nitrogen utilization of bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to herbicidal glutamine synthetase inhibitors are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides corresponding to herbicidal glutamine synthetase inhibitor-resistant polynucleotides are provided. Additionally, polypeptides corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides comprising a variant of SEQ ID NO:1, wherein the variant polynucleotide encodes a polypeptide that is resistant to inhibition by herbicidal glutamine synthetase inhibitor.

US Patent:

7960616, Jun 14, 2011

Filed:

Jan 30, 2009

Appl. No.:

12/362774

Inventors:

Volker Heinrichs - Raleigh NC, US
Laura Cooper Schouten - Pittsboro NC, US
Brian Vande Berg - Durham NC, US

Assignee:

Athenix Corp. - Morrisville NC

International Classification:

C12N 15/82
C12N 15/52

US Classification:

800300, 4352523, 4353201, 435419, 536 232, 800288, 800295

Abstract:

Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided, particularly polypeptide variants of SEQ ID NO:2 and 4. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:7-28, or the nucleotide sequence set forth in SEQ ID NO:29 or 30.

US Patent:

7989679, Aug 2, 2011

Filed:

Mar 2, 2007

Appl. No.:

11/681285

Inventors:

Michael G. Koziel - Raleigh NC, US
Laura Cooper Schouten - Pittsboro NC, US
Brian Vande Berg - Durham NC, US

Assignee:

Athenix Corp. - Morrisville NC

International Classification:

C12N 15/82

US Classification:

800300, 800268, 800298

Abstract:

Compositions and methods for increasing enzyme activity across a broad physiological spectrum in plants, plant cells, tissues and seeds are provided. Compositions include plants or plant parts comprising two or more polynucleotides encoding polypeptides that are active across a broader physiological spectrum than when either polynucleotide is expressed alone. Vectors comprising these polynucleotide molecules as well as host cells comprising the vectors are further provided. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In addition, methods are provided for producing the plants, plant cells, tissues and seeds of the invention. Methods for increasing plant yield and methods for conferring resistance to an herbicide in a plant are further provided.

US Patent:

8101389, Jan 24, 2012

Filed:

Feb 15, 2011

Appl. No.:

13/027666

Inventors:

Nicholas B. Duck - Apex NC, US
Todd K. Hinson - Rougemont NC, US
Vadim Beilinson - Cary NC, US
Laura Cooper Schouten - Pittsboro NC, US
Daniel John Tomso - Bahama NC, US

Assignee:

Athenix Corp - Morrisville NC

International Classification:

C12N 9/00

US Classification:

435183, 435232

Abstract:

Compositions and methods for conferring herbicide resistance to and improving nitrogen utilization of bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a polypeptide that confers resistance or tolerance to herbicidal glutamine synthetase inhibitors are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides corresponding to herbicidal glutamine synthetase inhibitor-resistant polynucleotides are provided. Additionally, polypeptides corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides comprising a variant of SEQ ID NO:1, wherein the variant polynucleotide encodes a polypeptide that is resistant to inhibition by herbicidal glutamine synthetase inhibitor.

US Patent:

8247535, Aug 21, 2012

Filed:

May 5, 2011

Appl. No.:

13/101351

Inventors:

Volker Heinrichs - Raleigh NC, US
Laura Cooper Schouten - Pittsboro NC, US
Brian Vande Berg - Durham NC, US

Assignee:

Athenix Corp. - Research Triangle Park NC

International Classification:

C12N 15/88
A61K 38/43
A61K 380/00

US Classification:

530350, 435462, 435440

Abstract:

Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided, particularly polypeptide variants of SEQ ID NO:2 and 4. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:7-28, or the nucleotide sequence set forth in SEQ ID NO:29 or 30.

US Patent:

8252980, Aug 28, 2012

Filed:

Aug 13, 2010

Appl. No.:

12/856021

Inventors:

Laura Cooper Schouten - Pittsboro NC, US
Cheryl L. Peters - Raleigh NC, US
Brian Vande Berg - Durham NC, US

Assignee:

Athenix Corp. - Research Triangle Park NC

International Classification:

C12N 1/21
C12N 15/52
C12N 15/82

US Classification:

800300, 435 691, 4352523, 4353201, 435419, 536 232, 800288, 8003001

Abstract:

Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 31, or the nucleotide sequence set forth in SEQ ID NO: 30.

US Patent:

8252981, Aug 28, 2012

Filed:

Aug 13, 2010

Appl. No.:

12/856058

Inventors:

Laura Cooper Schouten - Pittsboro NC, US
Brian Vande Berg - Durham NC, US
Volker Heinrichs - Raleigh NC, US

Assignee:

Athenix Corp. - Research Triangle Park NC

International Classification:

C12N 1/21
C12N 15/52
C12N 15/82

US Classification:

800300, 435 691, 4352523, 4353201, 435419, 536 232, 800288, 8003001

Abstract:

Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 33, or the nucleotide sequence set forth in SEQ ID NO: 32.