Laurence Ray Mccarthy

US Patent:

20030039957, Feb 27, 2003

Filed:

Nov 27, 2001

Appl. No.:

09/996187

Inventors:

Laurence McCarthy - Great Falls VA, US
Lilly Kong - Covina CA, US
Tang Shao - Rosemead CA, US
Xin Su - Irvine CA, US

International Classification:

C12Q001/70
C12Q001/68
G01N033/53
G01N033/554
G01N033/569

US Classification:

435/005000, 435/006000, 435/007100, 435/007320

Abstract:

Disclosed herein are methods for assaying the phenotype of a bioactive molecule in the presence and absence of compounds that are known inhibitors of the phenotypable activity of the bioactive molecule. Also disclosed are methods for discovering compounds that can inhibit the phenotypable activity of a bioactive molecule. The methods and assays of the present invention are useful in developing and monitoring a chemotherapy regimen for a patient, to detect or prevent the emergence of a drug resistant phenotype.

US Patent:

20060057643, Mar 16, 2006

Filed:

Sep 9, 2005

Appl. No.:

11/223785

Inventors:

Laurence McCarthy - Great Falls VA, US
Lilly Kong - Covina CA, US
Xin Su - Irvine CA, US
Tang Shao - Rosemead CA, US

International Classification:

C12Q 1/68
G01N 33/53

US Classification:

435007100, 435006000

Abstract:

The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human erythroviruses, such as the B19, V9, and A6 genotype, in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved region of the erythrovirus genomes. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.

US Patent:

20070250462, Oct 25, 2007

Filed:

Oct 30, 2006

Appl. No.:

11/590669

Inventors:

Jean Wilson - Huntington Beach CA, US
Jim Williamson - Long Beach CA, US
Mary Mosch - Sparks MD, US
Laurence McCarthy - Great Falls VA, US
Rick Lustig - Mission Viejo CA, US

International Classification:

G06N 3/12

US Classification:

706013000

Abstract:

Computer-based methods and systems for facilitating assessment of results of genetic screening tests are provided. The methods and systems can be implemented to, for example, facilitate a risk assessment revision for a subject who may be a carrier of a genetic disease or facilitate a diagnosis of a genetic disease.

US Patent:

20140178872, Jun 26, 2014

Filed:

Jan 31, 2012

Appl. No.:

13/982299

Inventors:

- Mansfield MA, US
Sergey V. Voronov - Sharon MA, US
Laurence R. McCarthy - Great Falls VA, US
Lilly I. Kong - Covina CA, US
Vesselin Tenkov Diankov - Franklin MA, US

Assignee:

PRIMERADX, INC. - Mansfield MA

International Classification:

C12Q 1/68

US Classification:

435 611

Abstract:

Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.

Address:

888 3 Quarter Pt Rd, Wirtz, VA 24184

VIN:

4S4BP62C377339413

Make:

SUBA

Model:

LEGA

Year:

2007