Lei L Zhang

US Patent:

20110207622, Aug 25, 2011

Filed:

Feb 10, 2011

Appl. No.:

13/025130

Inventors:

David T. WONG - Beverly Hills CA, US
Lei Zhang - Los Angeles CA, US
Hua Xiao - Irvine CA, US
Hui Zhou - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C40B 30/04
C12Q 1/68
C40B 30/00
C12Q 1/02
G01N 33/566
G01N 21/64
C07K 17/00
C07H 21/00
G01N 33/48
H01J 49/26

US Classification:

506 9, 435 614, 435 612, 506 7, 435 29, 435 71, 436501, 435 613, 5303911, 536 2433, 435 792, 73 6143, 250282

Abstract:

Presented herein are biomarkers related to lung cancer. The presently identified salivary biomarkers create the basis for a lung cancer detection bioassay with sensitivity and specificity. Means and methods for evaluating the data generated using multiple biomarkers in order to validate findings and further use of the multiplexed lung cancer assay in clinical, diagnostic and therapeutic uses is also included.

US Patent:

20110212851, Sep 1, 2011

Filed:

Feb 10, 2011

Appl. No.:

13/025110

Inventors:

David T. WONG - Beverly Hills CA, US
Lei Zhang - Los Angeles CA, US
Hua Xiao - Irvine CA, US
Hui Zhou - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C40B 30/04
C12Q 1/32
C12Q 1/527
C12Q 1/68
C40B 30/00
G01N 33/573
G01N 33/566
G01N 21/64
C12Q 1/02
C07K 17/00
C07H 21/00
G01N 33/48
H01J 49/26

US Classification:

506 9, 435 26, 435 4, 435 612, 506 7, 436501, 435 74, 435 792, 435 71, 435 29, 5303911, 536 2433, 73 6143, 250282

Abstract:

Presented herein are biomarkers related to breast cancer. The presently identified salivary biomarkers create the basis for a breast cancer detection bioassay with sensitivity and specificity. Means and methods for evaluating the data generated using multiple biomarkers in order to validate findings and further use of the multiplexed breast cancer assay in clinical, diagnostic and therapeutic uses is also included.

US Patent:

20120196764, Aug 2, 2012

Filed:

Jun 25, 2010

Appl. No.:

13/379341

Inventors:

Lei Zhang - Los Angeles CA, US
David T. Wong - Beverly Hills CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C40B 30/04
C12Q 1/68

US Classification:

506 9, 435 612

Abstract:

The present invention relates to the identification of pancreatic cancer biomarkers for the detection of early pancreatic cancer. The present invention also provides methods of diagnosing pancreatic cancer and distinguishing between pancreatic cancer and chronic pancreatitis. The present invention additionally provides kits that find use in the practice of the methods of the invention.

US Patent:

20220221968, Jul 14, 2022

Filed:

Dec 17, 2021

Appl. No.:

17/644989

Inventors:

- Santa Monica CA, US
Andrew Grosvenor Cooper - Los Angeles CA, US
Yamill Antonio Vallecillo - Los Angeles CA, US
Sivakumar Loganathan - San Francisco CA, US
Lei Zhang - Mountain View CA, US

International Classification:

G06F 3/0485
G06F 3/0481
H04N 5/232
G06F 3/04883
H04N 21/47
H04N 21/431

Abstract:

A panoramic system can receive content (e.g., live video) recorded in a landscape orientation and use a portrait dynamic crop window to display a portrait area of the received content. The panoramic system can further display the content in a landscape dynamic crop window that has a moveable user interface control that can pan the portrait crop window as the content plays in one or both of the dynamic crop windows.

US Patent:

20180090058, Mar 29, 2018

Filed:

Sep 21, 2017

Appl. No.:

15/711965

Inventors:

- Hong Kong, HK
Fang Ou - Monterey Park CA, US
Wing Cheung Chong - Tseung Kwan O, HK
Lei Zhang - Albuquerque NM, US
Qiming Li - Albuquerque NM, US

International Classification:

G09G 3/32
H01L 33/60

Abstract:

A display panel with integrated micro-reflectors. The display panel also includes an array of pixel light sources (e.g., micro-LEDs) electrically coupled to corresponding pixel driver circuits (e.g., FETs). The micro-LEDs produce light and the micro-reflectors reduce the divergence of the light produced by the micro-LEDs. Different designs are possible. The micro-reflectors can have different shapes, include the shape of their sidewalls and the shape of their plan cross-section. The array schemes can also vary, including the number of LEDs per micro-reflector. Different fabrication approaches are also possible. In one approach, a support structure is integrated between micro-LEDs. The sides of the support structure are reflective and serve as the reflective sidewalls of the micro-reflector. Alternately, the LED mesa itself can serve as the support structure.

US Patent:

20170306414, Oct 26, 2017

Filed:

Apr 25, 2017

Appl. No.:

15/496277

Inventors:

- Oakland CA, US
Lei ZHANG - Los Angeles CA, US
Hua XIAO - Los Angeles CA, US
Hui ZHOU - Los Angeles CA, US

International Classification:

C12Q 1/68
C12Q 1/68
C12Q 1/68
C12Q 1/68
G01N 33/574
G01N 33/487

Abstract:

Presented herein are biomarkers related to lung cancer. The presently identified salivary biomarkers create the basis for a lung cancer detection bioassay with sensitivity and specificity. Means and methods for evaluating the data generated using multiple biomarkers in order to validate findings and further use of the multiplexed lung cancer assay in clinical, diagnostic and therapeutic uses is also included.

US Patent:

20170219586, Aug 3, 2017

Filed:

Apr 17, 2017

Appl. No.:

15/488832

Inventors:

- Oakland CA, US
Lei Zhang - Los Angeles CA, US
Hua Xiao - Los Angeles CA, US
Hui Zhou - Los Angeles CA, US

International Classification:

G01N 33/574
C12Q 1/68

Abstract:

Presented herein are biomarkers related to breast cancer. The presently identified salivary biomarkers create the basis for a breast cancer detection bioassay with sensitivity and specificity. Means and methods for evaluating the data generated using multiple biomarkers in order to validate findings and further use of the multiplexed breast cancer assay in clinical, diagnostic and therapeutic uses is also included.

US Patent:

20160115192, Apr 28, 2016

Filed:

Jun 10, 2014

Appl. No.:

14/895421

Inventors:

- Los Angeles CA, US
Bong Seop Lee - Torrance CA, US
Lei Zhang - Los Angeles CA, US

Assignee:

Cedars-Sinai Medical Center - Los Angeles CA

International Classification:

C07J 73/00
A61K 49/00
A61K 9/14

Abstract:

This invention relates to uses of conjugates of triptolide nanoprodrugs in cancer immunotherapy, specifically compound such as D-I or D-II wherein Xis a antioxidant, an anti-inflammatory or an anti-cancer agent and nanospheres thereof, and A is be selected from the group consisting of branched and unbranched alkyl, branched and unbranched alkenyl, branched and unbranched alkynyl, heteroatom-containing branched and unbranched alkyl, heteroatom-containing branched and unbranched alkenyl, heteroatom-containing branched and unbranched alkynyl, aryl, cyclic aliphatic, cyclic aromatic, heterocyclic, and aromatic heterocyclic groups.