Li Tang

US Patent:

20130072554, Mar 21, 2013

Filed:

Sep 11, 2012

Appl. No.:

13/609531

Inventors:

Yuesheng Zhang - Orchard Park NY, US
Arup Bhattacharya - Buffalo NY, US
Li Tang - Lancaster NY, US
Yun Li - Orchard Park NY, US
Joseph D. Paonessa - Niagara Falls NY, US
Feng Geng - Columbus OH, US
Yi Ding - Buffalo NY, US

Assignee:

HEALTH RESEARCH, INC. - Buffalo NY

International Classification:

A61K 31/26
A61K 36/31

US Classification:

514515

Abstract:

Provided is a composition that contains a mixture of broccoli seed and mustard seed. Before mixing the broccoli seed with the mustard seed, the broccoli seed is subjected to baking and a pressurized heat treatment. The broccoli seed is baked at a temperature of at least 200 degrees Fahrenheit for at least 60 minutes, and is subjected to a pressurized heat treatment of at least 200 degrees Fahrenheit at a pressure of at least 10 pounds/square inch for at least 5 minutes. Also provided is a method for therapy and/or prophylaxis of bladder cancer in an individual. The method entails administering orally to the individual a composition that contains an isothiocyanate (ITC) or a derivative thereof such that the administration inhibits the growth and/or recurrence of bladder cancer. Nutraceutical compositions are also provided.