Liang Wang

US Patent:

6387920, May 14, 2002

Filed:

Apr 11, 2001

Appl. No.:

09/833392

Inventors:

Verena D. Huebner - Benicia CA
Xiaodong Lin - Walnut Creek CA
Ian James - Rowville, AU
Liya Chen - East Brunswick NJ
Manoj Desai - Pleasant Hill CA
Jennifer C. Moore - Emeryville CA
Beata Krywult - Armadale, AU
Thayalan Navaratnam - San Leandro CA
Rajinder Singh - San Francisco CA
Rob Trainor - Murrumbeena, AU
Liang Wang - Lafayette CA

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

A61K 3144

US Classification:

514293, 546 83

Abstract:

Isoxazole estrogen receptor agonist and antagonist compounds having unexpected and surprising activity in modulating estrogen receptor activity are described. In addition, methods and compositions for treating or preventing estrogen receptor-mediated disorders are disclosed. The compounds, methods, and compositions of the invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimers disease.

US Patent:

6727273, Apr 27, 2004

Filed:

Sep 18, 2001

Appl. No.:

09/954039

Inventors:

Verena D. Huebner - Benicia CA
Xiaodong Lin - Walnut Creek CA
Ian James - Rowville, AU
Liya Chen - East Brunswick NJ
Manoj Desai - Pleasant Hill CA
Beata Krywult - Armadale, AU
Rajinder Singh - San Francisco CA
Liang Wang - Lafayette CA

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

A61K 31416

US Classification:

514406, 5483591

Abstract:

Estrogen receptor-modulating pyrazole compounds are described in addition to methods and compositions for treating or preventing estrogen receptor-mediated disorders. The compounds described have been found to have unexpected and surprising activity in modulating estrogen receptor activity. Thus, the compounds of the present invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimers disease.

US Patent:

6743815, Jun 1, 2004

Filed:

Apr 25, 2002

Appl. No.:

10/134302

Inventors:

Verena D. Huebner - Benicia CA
Xiaodong Lin - Walnut Creek CA
Ian James - Rowville, AU
Liya Chen - East Brunswick NJ
Manoj Desai - Pleasant Hill CA
Jennifer C. Moore - Emeryville CA
Beata Krywult - Armadale, AU
Thayalan Navaratnam - San Leandro CA
Rajinder Singh - San Francisco CA
Rob Trainor - Murrumbeena, AU
Liang Wang - Lafayette CA

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

A61K 3142

US Classification:

514378, 548240

Abstract:

Isoxazole estrogen receptor agonist and antagonist compounds having unexpected and surprising activity in modulating estrogen receptor activity are described. In addition, methods and compositions for treating or preventing estrogen receptor-mediated disorders are disclosed. The compounds, methods, and compositions of the invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimers disease.

US Patent:

6869969, Mar 22, 2005

Filed:

Nov 13, 2003

Appl. No.:

10/713621

Inventors:

Verena D. Huebner - Benicia CA, US
Xiaodong Lin - Walnut Creek CA, US
Ian James - Rowville, AU
Liya Chen - East Brunswick NJ, US
Manoj Desai - Pleasant Hill CA, US
Jennifer C. Moore - Emeryville CA, US
Beata Krywult - Armadale, AU
Thayalan Navaratnam - San Leandro CA, US
Rajinder Singh - San Francisco CA, US
Rob Trainor - Murrumbeena, AU
Liang Wang - Lafayette CA, US

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

A61K031/42
C07D261/02
C07D261/06

US Classification:

514378, 548240, 548247

Abstract:

Isoxazole estrogen receptor agonist and antagonist compounds having unexpected and surprising activity in modulating estrogen receptor activity are described. In addition, methods and compositions for treating or preventing estrogen receptor-mediated disorders are disclosed. The compounds, methods, and compositions of the invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimer's disease.

US Patent:

RE39708, Jun 26, 2007

Filed:

Jan 13, 2004

Appl. No.:

10/757347

Inventors:

Verena D. Huebner - Benicia CA, US
Xiaodong Lin - Hercules CA, US
Ian James - Rowville, AU
Liya Chen - East Brunswick NJ, US
Manoj C. Desai - Pleasant Hill CA, US
Beata Krywult - Oakleigh East, AU
Rajinder Singh - Belmont CA, US
Liang Wang - Lafayette CA, US

Assignee:

Chiron Corporation - Emeryville CA

International Classification:

A61K 31/415
A61P 19/10
C07D 231/12

US Classification:

514406, 5483771

Abstract:

Estrogen receptor-modulating pyrazole compounds are described in addition to methods and compositions for treating or preventing estrogen receptor-mediated disorders. The compounds described have been found to have unexpected and surprising activity in modulating estrogen receptor activity. Thus, the compounds of the present invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimer's disease.

US Patent:

8638334, Jan 28, 2014

Filed:

Nov 25, 2008

Appl. No.:

12/323242

Inventors:

Hailin Jin - San Jose CA, US
Liang Wang - Lexington KY, US

Assignee:

Adobe Systems Incorporated - San Jose CA

International Classification:

G06T 15/00

US Classification:

345520, 345419, 345582

Abstract:

Techniques for selectively displaying surfaces of an object model to a user are described. In one embodiment, a computer-implemented method may include, for a given one of a plurality of surfaces included in an object model that is representative of a physical object, determining a normal vector of the given surface. The method may also include determining an angle between the normal vector of the given surface and a current viewing direction of the model. The method may further include displaying the object model to a user without displaying the given surface to the user, dependent upon determining that the angle between the normal vector and the current viewing direction is greater than a threshold value.

US Patent:

20040077701, Apr 22, 2004

Filed:

Jun 12, 2003

Appl. No.:

10/461914

Inventors:

Verena Huebner - Benicia CA, US
Xiaodong Lin - Walnut Creek CA, US
Ian James - Rowville, AU
Liya Chen - East Brunswick NJ, US
Manoj Desai - Pleasant Hill CA, US
Beata Krywult - Armadale, AU
Rajinder Singh - San Francisco CA, US
Liang Wang - Lafayette CA, US

Assignee:

CHIRON CORPORATION - Emeryville CA

International Classification:

C07D231/02
C07D231/08
A61K031/415

US Classification:

514/406000, 548/364100, 548/366100, 548/367400

Abstract:

Estrogen receptor-modulating pyrazole compounds are described in addition to methods and compositions for treating or preventing estrogen receptor-mediated disorders. The compounds described have been found to have unexpected and surprising activity in modulating estrogen receptor activity. Thus, the compounds of the present invention have utility in preventing or treating estrogen receptor-mediated disorders such as osteoporosis, breast and endometrial cancers, atherosclerosis, and Alzheimer's disease.

US Patent:

20130126867, May 23, 2013

Filed:

May 2, 2012

Appl. No.:

13/462676

Inventors:

Liang Wang - Milpitas CA, US
Ilyas Mohammed - Santa Clara CA, US
Masud Beroz - Morrisville NC, US

Assignee:

INVENSAS CORPORATION - San Jose CA

International Classification:

H01L 29/06
H01L 29/04
H01L 29/12
H01L 33/08
H01L 21/20

US Classification:

257 52, 438 34, 438486, 257618, 257 76, 257E33002, 257E2109, 257E29022, 257E29068, 257E29003

Abstract:

High yield substrate assembly. In accordance with a first method embodiment, a plurality of piggyback substrates are attached to a carrier substrate. The edges of the plurality of the piggyback substrates are bonded to one another. The plurality of piggyback substrates are removed from the carrier substrate to form a substrate assembly. The substrate assembly is processed to produce a plurality of integrated circuit devices on the substrate assembly. The processing may use manufacturing equipment designed to process wafers larger than individual instances of the plurality of piggyback substrates.