Lihong Yang - Manhasset NY, US Kevin J. Tracey - Old Greenwich CT, US
Assignee:
The Feinstein Institute for Medical Research - Manhasset NY
International Classification:
A61K 39/395 C07K 16/00 A61P 29/00
US Classification:
4241331, 5303879, 5303873, 4241391
Abstract:
An antibody or an antigen binding fragment thereof which binds to mammalian α7 subunit of a nicotinic acetylcholine receptor or its functional variant and which is an agonist of said receptor or variant. Pharmaceutical compositions comprising same. A method of treating a subject suffering from an inflammatory condition comprising administering to said subject an antibody or an antigen-binding fragment as described herein.
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