Lin Qing Chen

US Patent:

8076070, Dec 13, 2011

Filed:

Aug 6, 2009

Appl. No.:

12/537138

Inventors:

Lin Chen - Los Angeles CA, US
Reza Kalhor - Los Angeles CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

C12Q 1/68
G01N 33/53
C12P 19/34
C07H 21/00
C07H 21/02
C07H 21/04

US Classification:

435 6, 435 71, 435 912, 536 221, 536 231, 536 243

Abstract:

The invention relates to the use of GCC (Genome Conformation Capture) technology in determining the three dimensional arrangement of an entire genome.

US Patent:

20020180753, Dec 5, 2002

Filed:

Jun 4, 2001

Appl. No.:

09/871632

Inventors:

Lin Chen - La Canada CA, US

International Classification:

G09G005/02

US Classification:

345/591000

Abstract:

A method of establishing a color image space model including the steps of: (a) setting a standard color card containing a series of reference colors for use as a color data bank, and then setting a table of relative adjectives; (b) setting a color comment questionnaire subject to the standard color card and table of relative objectives thus obtained; (c) selecting at least one particular group people to make an investigation subject to the set color comment questionnaire, and then collecting and arranging the investigation result thus obtained so as to set up effective statistic data; and (d) using an analysis mode to compute the effective statistic data thus obtained, so as to establish a specific color image space model.

US Patent:

20070007512, Jan 11, 2007

Filed:

May 22, 2006

Appl. No.:

11/438180

Inventors:

Nada Dimitrijevic - Downers Grove IL, US
Tijana Rajh - Naperville IL, US
Zoran Saponjic - Forest Park IL, US
Bryan Rabatic - Woodridge IL, US
David Tiede - Elmhurst IL, US
Lin Chen - Naperville IL, US
Peter Zapol - Darien IL, US

International Classification:

H01L 51/00
C12Q 1/68

US Classification:

257040000, 435006000, 438001000, 977702000

Abstract:

A method for producing a bio-inorganic conjugate is provided comprising supplying a plurality of inorganic particles that are axially anisotropic; and positioning biomolecules intermediate the particles to form a chain-like structure. Also provided is an organized microscopic structure capable of vectorial electron transport within the structure, comprising a plurality of inorganic oxide particles, each particle having at least two ends; a first molecule covalently attached to each end to form a plurality of constructs; and a second molecule attached to the first molecule so as to link the constructs and form an elongated substrate.

US Patent:

20110275674, Nov 10, 2011

Filed:

Nov 5, 2009

Appl. No.:

12/613521

Inventors:

Lin Chen - La Canada CA, US
Nimanthi Jayathilaka - Los Angeles CA, US
Aidong Han - Los Angeles CA, US
Nicos A. Petasis - Hacienda Heights CA, US

Assignee:

UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA

International Classification:

A61K 31/444
C07C 237/20
C12Q 1/68
C12N 15/63
C12N 5/07
G06G 7/58
A61K 31/167
A61P 35/00
A61P 25/28
A61P 9/00
G01N 33/68
C07D 401/12
C12N 9/99

US Classification:

514332, 546265, 564157, 435 613, 4353201, 435375, 435184, 514616, 436501, 703 11

Abstract:

Disclosed are methods and compositions for modulating the function of transcription factors, especially transcription factors that recruit epigenetic regulators (histone modifying enzymes) to specific DNA promoters. The targeted transcription factors include but are not limited to the myocyte enhancing factor (MEF2), the forkhead/winged helix transcription factor FOXP3 and the transcription factor GATA3. Also disclosed are small molecule modulators of MEF2 and its associated factors that include but not limited to histone deacetylases (HDACs), p300/CBP and Cabin1 and the therapeutic applications thereof.

US Patent:

20110287947, Nov 24, 2011

Filed:

May 18, 2010

Appl. No.:

12/782616

Inventors:

Lin Chen - Los Angeles CA, US
Reza Kalhor - Los Angeles CA, US

Assignee:

UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA

International Classification:

C40B 30/00
C12Q 1/68

US Classification:

506 7, 435 619

Abstract:

Disclosed are methods and systems for determining the three-dimensional structure of chromatin in eukaryotic cells. More specifically, disclosed are methods and systems for obtaining chromatin structural information by surface immobilization, i.e tethering crosslinked protein:DNA complexes and/or ligated DNA complexes to media such as beads, gels, and or matrices during the conformation capture assay. In general, the method includes contacting a cell with a cross-linking reagent to cross-link DNA and protein in the cell; lysing the cell, producing cross-linked protein:DNA complexes by cutting the chromatin using a chemical, physical or enzymatic method, substantially immobilizing the cross-linked protein:DNA complexes, ligating the cross-linked protein:DNA complexes intramolecularly such that the ligated protein:DNA complexes represent structural organization of the chromatin; characterizing the ligated DNA by sequencing or other methods; and identifying any structural organization of the chromatin. The structural organization preferably includes information relating to interacting loci of the chromatin.

US Patent:

52257886, Jul 6, 1993

Filed:

Sep 20, 1991

Appl. No.:

7/762966

Inventors:

James R. Norris - Downers Grove IL
Jau-Huei Tang - Naperville IL
Lin Chen - Naperville IL
Marion Thurnauer - Downers Grove IL

Assignee:

The United States of America as represented by the United States
Department of Energy - Washington DC

International Classification:

H05H 708

US Classification:

328235

Abstract:

An apparatus for selecting a single synchrotron pulse from the millions of pulses provided per second from a synchrotron source includes a rotating spindle located in the path of the synchrotron pulses. The spindle has multiple faces of a highly reflective surface, and having a frequency of rotation f. A shutter is spaced from the spindle by a radius r, and has an open position and a closed position. The pulses from the synchrotron are reflected off the spindle to the shutter such that the speed s of the pulses at the shutter is governed by: s=4. times. pi. times. r. times. f. such that a single pulse is selected for transmission through an open position of the shutter.

US Patent:

20230129198, Apr 27, 2023

Filed:

Oct 27, 2021

Appl. No.:

17/512412

Inventors:

- Kirkland WA, US
Zhongwei Cheng - Redmond WA, US
Steve Skeoch - Palos Verdes Estates CA, US
Lin Chen - Seattle WA, US
Hongfei Ning - Bothell WA, US

International Classification:

G06K 9/00
E05F 15/668
E05F 15/73
G06N 20/00
G06K 7/14

Abstract:

A method performed by an image capture device. The method includes determining whether to send a notification or determining whether to open a door based at least in part on at least one image captured by the image capture device.

US Patent:

20230086995, Mar 23, 2023

Filed:

Sep 20, 2021

Appl. No.:

17/479832

Inventors:

- Kirkland WA, US
Steve Skeoch - Palos Verdes Estates CA, US
Lin Chen - Seattle WA, US
Zhongwei Cheng - Redmond WA, US

International Classification:

H01R 33/945
H01R 33/92
H04N 7/18

Abstract:

A lamp socket assembly to be installed in a light socket and receive electrical power therefrom. The lamp socket assembly to provide electrical power to a surveillance device that detects an occurrence of a security event and notifies the lamp socket assembly of the occurrence. In response to the notification, the lamp socket assembly to turn on a light bulb.